Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

알루미나/Mo 복합체의 미세구조와 파괴인성에 미치는 제3상 첨가의 영향

배원태,김용진,최태현,정원도 국립경상대학교 공과대학 부설 첨단소재연구소 1993 尖端素材 Vol.3 No.-

In order to improve the fracture toughness of alumina-Mo composite, three-component systems has been studied : Al₂O₃-Mo-CeO₂, Al₂O₃-M0-(TZ-2Y), and Al₂O₃-Mo-(Ce-TZP). The particle size and volume fraction of Mo in alumina were fixed at 0.6㎛ and 5 vol.%. The microstructural change and the fracture toughness of these systems were analyzed. When the Ce-nitrate as CeO₂source was added, Mo and Ce-β-alumina were observed in the alumina matrix. When 2 mole% of Ce-nitrate was added as colloidal form, the composite showed a maximum fracture toughness(about 5.8MN/m?). However, standard deviaton of fracture toughness was large because of the nonhomogenity of the microstructure. On the other hand, when Ce-nitrate was added as solution, the higher the Ce-nitrate content, the lower the fracture toughness of the composite. When the TZ-2Y was added, Mo, ZrO₂(m), and ZrO₂(t) were observed in the alumina matrix. This composite showed a maximum fracture toughness(about 5.2MN/m) at 15 vol.% of TZ-2Y. When the Ce-TZP was added, Mo, Ce-β-alumina, ZrO₂(m), and ZrO₂(t) were observed in the aluminal matrix. This composite showed a maximum fracture toughness(about 6.3MN/m?) at 30 wt.% of Ce-TZP. This value is larger than that of hot pressed alumina/0.6 ㎛-5 vol.% Mo composite(about 6.1MN/m?).

치과응용을 위한 알루미나-유리 복합체 제조

배태성,이민호,강동진,원대희,진영철 大韓齒科器材學會 2000 대한치과재료학회지 Vol.27 No.3

The purpose of this study was to evaluate the mechanical properties of alumina-glass dental composites. Four different borosilicate glasses containing 1, 2, 3, 4 mol% Li₂O were prepared. Porous alumina compacts of 12.0 mm in diameter and 1.0 mm in thickness were prepared with alumina powders of 1.8 and 4.6㎛ by slip casting and sintered at 1,120℃ for 2 hours. Dense composites were made by infiltration of molten glass into partially sintered alumina at 1200℃ for 6 hours. All samples were polished sequentially from #600 to #2,000 diamond disk, and the final surface finishing on the tensile side was received an additional polishing sequence through 0.3㎛ diamond paste. Apparent porosity of alumina-glass composites was measured by means of the KS L3114 method. Biaxial flexure test was conducted by using ball-on-three-ball method at a crosshead speed of 0.5 mm/min. To examine the microstructural aspect of crack propagation, Vickers-produced indentation crack and fracture surfaces were examined by SEM. The results obtained were summarized as follows; 1. Apparent porosity rate decreased according to the increasing with the particle size of alumina. 2. The maximum biaxial flexure strength of 365.26 MPa was obtained with an addition of 4 mol% Li₂O in glass composition. 3. The maximum fracture toughness of3.95 MPa·m½ was obtained with an addition of 3 mol% Li₂O. 4. The crack deflection and crack bridging were the principal strengthening mechanisms in the alumina-glass composites.

이동 애드 혹 네트워크에서의 환경적응형 QoS AODV 라우팅 프로토콜에 관한 연구

裵振勝,宋東勳,吳世德,鄭燦赫,金玄郁,李光培,文泰洙,郭承郁,河載承 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

In this paper, we propose a bidirectional mobile Ad Hoc routing protocol based on AODV(ad-hoc on-demand distance vector routing) with QoS(quality of service) support. At presence, wireless mobile communication focuses on how to efficiently support mobility of users more than QoS guarantee. However, in order to satisfy requirement of various applications which have been or will be served, QoS guarantee between end points is a very important issue. The existing AODV routing protocol is implemented to use only BE (Best Effort) service. However, actual wireless mobile environment requires to reduce a waste of communication resources and meet with the real-time change of data paths by setting up routes with QoS support, considering available communication resources at each node in advance. Therefore, in this thesis, we propose an adaptive QoS support method using hello message in order to rapidly meet with the change of available communication resources and to smoothly perform route maintenance. For performance evaluation, we analyzed the average data reception rate. At that time, we used evaluation parameters such as node's mobility-stop time, hello message period, and packet priority, considering the node's mobility and the number of best effort/QoS data flows. As results, we found that with our proposed method the average data reception rate was increased 16.293%, 15.914%, 17.238% for 300 mobility-stop second case and 4.809%, 4.264%, 2.956% for 300 mobility-stop second case.

가열 및 저장중 고추 oleoresin의 지질산화 및 항산화성

배태진,김현주,강훈이,최옥수 여수대학교 1994 論文集 Vol.8 No.-

Changes of lipid oxidation and antioxidative activity in modified oleoresin during heat treatment and storage were investigated. Lipid oxidation occurred somewhat to oleoresin red pepper after heat treatment for 5 hours at 150℃ and 200℃, whereas in the heat treatment at 50℃ and 100℃, occurred in little. During heat treatment for 5 hours at 100℃, oleoresin red pepper had a moderate antioxidation effect, but its antioxidation effect at 200℃ was not shown due to degradation of capsaicin. And oleoresin red pepper greatly inhibited the oxidation of soybean oil during storage at 25℃ and 40℃.

이용도가 낮은 수산자원의 효소적 가수분해 조건

배태진 한국식품영양학회 1998 韓國食品營養學會誌 Vol.11 No.4

이용율이 낮고 다획성인 자원의 효과적인 이용을 위하여 전어체를 가수분해시키는 공정을 검토하였다. 시료인 풀치, 전어, 강달이, 키조개 및 굴의 체내효소에 의한 자가소화의 최적온도는 각각 35℃, 45℃, 30℃, 30℃ 및 30℃, Alcalase를 첨가하였을 때의 최적온도는 각각 60℃, 50℃, 50℃, 50℃ 및 50℃, Protease N. P.를 첨가하였을 때는 각각 55℃, 60℃, 50℃, 50℃, 및 50℃부근이었다. 특히 외부효소를 첨가하였을 경우 시료에 함유된 체내 효소가 동시에 작용하여도 가수분해율은 첨가효소의 최대 활성 온도 부근영역에서 가장 높아, 체내 효소에 의한 가수분해효과보다 외부에서 첨가한 효소에 의하여 가수분해가 좌우되었다. 그리고 Alcalase와 Protease N.P.를 이용한 가수분해에서 5종의 시료 모두가 pH 9 부근에서 가장 높은 가수분해를 보였다. 가수분해가 최대로 일어나는 때를 적정 분해시간으로 간주할 때 모든 시료에서 6시간으로 결정되었다. 외부에서 첨가하는 상업적 효소의 경제적인 적정 첨가농도를 구하기 위하여 단위시간 동안 단위효소량이 분해하는 아미노질소량에 대한 효소 활성의 개념으로 동력학적 고찰을 하여 최적 첨가량을 결정하였는데 풀치, 전어, 강달이, 키조개 및 굴의 경우 Alcalase와 Protease N.P.의 적정 첨가농도는 각각 3.0%, 4.5%, 3.5%, 3.0% 및 3.0%이었다. In present work, the development of processing for various fermented sea foods using low-usefulness marine resources were investigated. The optimum temperatures of autolysis were 35℃ for hair tail, 45℃ for gizzard shad, 30℃ for kangdale, 30℃ for pen shell and 30℃ for oyster and when alcalase(Novo Co) were added, optimum temperatures were 60℃, 50℃, 50℃, 50℃ and 50℃, respectively, and protease N.P.(Pacific chem. enzyme mixture 2,000) were 55℃, 60℃, 50℃, 50℃ and 50℃, respectively. Especially although exozymes and endozymes reacted at same time, hydrolysis rate of raw materials got to maximum at optimum temperatures of exozymes. The facts showed that exozymes dominated the hydrolysis of raw materials. When alcalase and protease N.P. were added the hydrolysis rate of 5 raw materials reached maximum at pH 9.0, and optimum hydrolysis time of all raw materials were 6 hours. And the optimum concentrations of exozymes were about 3.0% for hair tail, 4.5% for gizzard shad, 3.5% for kangdale, 3.0% for pen shell and 3.0% for oyster, respectively.

참모자반 2단추출액의 유동특성

배태진 여수대학교 산업기술지역개발연구소 2000 産業基術硏究所 論文集 Vol.9 No.-

The rheological property of gulf weed, Sargassum Fulvellum, extract at various concentration(Brix 5~20) was investigated. Gulf weed was extracted with two stage extraction, that extracted with 70% of ethyl alcohol at 25℃ for 1 hour I the first place, and reside was successively extracted with water(1:14, w/v) 70℃ for 2 hours. Gulf weed extract showed the movement of non-Newtonian fluid and pseudoplastic property was typically emerged. The shear rate dependence of apparent viscosity in the gulf weed extract increased as concentration go higher. As the measuring concentration of extract increase from Brix 5 to Brix 20 under constant temperature, flow behavior index(n) was decreased, whereas, consistency index(K) was increased. The flow behavior indexes in the range of Brix 5~20 of gulf weed extract were 0.68~0.85, consistency indexes were 0.0343~1.1820 Pa×s□ at 30℃. And the yield stresses were 0.002~0.885 Pa. As the measuring temperature increase from 10°C to 40℃, n was increased. Whereas, K was decreased and existence nature of temperature followed Arrhenius equation. And the activation energy of gulf weed extract with the range of Brix 5~20 was 2,0635~3.1958 J/kg×mol. And at this time rate constants(k□) and frequency factor(A) were 0.7734~1.6793×10□Pa×s and 0.1274~0.1524 Brix□, respectively.

호박 및 대추 자숙액즙의 살균조건

배태진 여수대학교 1998 論文集 Vol.13 No.2

Bacterial counts and quality changes of thermal treated pumpkin and jujube juices were investigated to determine an optimal sterilizing condition for microbiological safety and quality stability during long-term storage. The pumpkin and jujube juices were sterilized 96℃ and 115℃ with various time and stored at 5℃, 25℃ and 37℃ for 24 weeks. No remarkable quality changes in pH, swelling and leakage of pouch, appearance, taste, and odor of the pumpkin and jujube juices sterilized at 115℃ for 40 minutes, were recognized at all storage temperatures.

새우젓의 정미성분 분석

배태진 여수대학교 1994 論文集 Vol.8 No.-

To indicate basic data for quality standarization of fermented shrimp, the changes of free amino acids, nucleotide and their related cormpounds and betaine ete. during fermentation were analysed. A fermented shrimp was prepared with various contents of salt and additives such as 5% of ethyl alcohol and 5% of sorbitol, and fermented at 4℃ and 15℃ for 120 days. The major free amino acids in fermented shrimp determined after 120 days fermentation were glutamic acid, leucine, proline, lysine, glycine, aspartic acid, alanine and taurine which occupied 70% or over of the total free amino acids while taurine, proline, arginine, alanine, glycine and lysine occupied about 65.8% of them in raw shrimp. And hypoxanthine, IMP, inosine in fermented shrimp deternined after 120days fermentation were 20.1-42.8μmol/g, 4.3-11.1μmol/g and 1.1-3.6 mol/g, respectively. Contents of amino acid-N and nucleotide-N in fermented shrimp determined after 120 days fermentation occupied about 65.2-67.2% of total nitrogen compounds. It is supposed that these nitrogen compounds and betaine could play a role as the major taste compounds of fermented shrimp.

한국 약용식물부터 폴리폐놀류군의 분리 및 기능성화장품소제로서의 응용

배두경,김성기,고대원,이창언,이진태,안봉전 경산대학교 생명자원개발연구소 2001 생명자원과 산업 Vol.5 No.-

For develope the functional cosmetic material. we extracted the Korean persimmon leaves in 80% ethanol solution and isolated fraction I, II, III, to use Sephadex LH-20 column. Their polyphenol quantity was 20%, 70%, 82.8% individually and fraction II, III had polyphenol which included a many flavan-3-ol skeleton structure. We investigated various biological activity such a tyrosinase, xanthin oxidase inhibition, SOD-like acivity and DPPH. Inhibitory effect of tyrosinase was inhibited 51.7%, 74.7% at 50 ppm, 500 ppm of the fraction III and SOD-like activity increased quickly at 500ppm of the fraction II, III. DPPH effect had 80% electron donate ability at 50 ppm all of the fraction and xanthin oxidase was more inhibited 80% at 50 ppm of fraction II, III. These results showed possibility that polyphenols of the Korean persimmon leaves become the functional cosmetic ingredient