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Bae-Sung Kim(김배성),Hwa-Nyeon Kim(김화년),Man-Keun Kim(김만근),Seong-Bo Ko(고성보) 한국산학기술학회 2020 한국산학기술학회논문지 Vol.21 No.7
미국의 탄저린 감귤귤 재배면적은 2009년 19,000ha에서 2016년 27,000ha로 급격히 증가하여 7년 동안 42% 증가했다. 최근 일본으로의 수출이 급증함에 따라 향후 약 6 ~7천 톤의 수출량이 증가할 가능성이 높다. 따라서, 본연구의 목적은 미국 탄저린 수입이 감귤산업에 미치는 경제적 파급효과를 다양한 시나리오를 통해 시뮬레이션 분석을 하는데 있다. 미국 탄저린감귤의 수입 가능성을 조사하기 위해 미국 감귤이 수입된 적인 없기 때문에 미국 탄저린 감귤의 일본 수출 단가가 사용되었다. 감귤류는 재배 방법과 품종에 따라 노지감귤, 하우스감귤, 한라봉 등 만감류(월동 온주 포함)로 분류하였다. 노지와 하우스감귤의 생산시즌을 고려해 보면, 미국 탄저리감귤의 수입량은 2021년 약 4,700 톤에서 2027년에는 10,000톤으로 증가할 것으로 예상된다. 미국 탄저린감귤의 수입은 국내산 노지와 하우스감귤의 생산량과 품질뿐만 아니라 미국산 탄저린감귤의 생산량에 따라 변동될 수 있다. 그렇지만, 미국 탄저린감귤의 관세율이 50% 이하로 떨어지는 2021년 이후에는 수입될 수 있다는 점을 명심해야 한다. The acreage of tangerines in the U.S. sharply rose from 19,000 ha in 2009 to 27,000 ha in 2016, an increase of 42% in 7 years. Considering the recent surge in tangerine exports to Japan, the export volume of 6-7 thousand tons is highly likely to increase in the future. Therefore, the purpose of this study was to analyze the economic impact of U.S. tangerine imports on the Korean citrus industry under various scenarios. In order to examine the possibility of imports of U.S. tangerines, the unit price of U.S. exports to Japan was used since U.S. tangerines are not imported to South Korea. Citrus fruits are divided into field citrus, house citrus, and late-maturing citrus (including winter season citrus) based on the cultivation method and variety used to analyze. Considering both the field and house seasons, the import volume of U.S. tangerines can be expected to rise from roughly 4,700 tons in 2021 to 10,000 tons in 2027. Imports of U.S. tangerines may be pushed up or delayed depending not only on the harvest method and quality of domestic field and house citrus but also on the harvest of U.S. tangerines. However, it is necessary to note that tangerines could be imported after 2021, when the tariff rate on U.S. tangerines will fall below 50%.
Bae, Ji-Suk,Park, Jung-Han,Park, Yoo-Keun,Kim, Jong-Yeon,Lee, Sang-Won,Park, Soon-Woo The Korean Society for Preventive Medicine 2011 Journal of Preventive Medicine and Public Health Vol.44 No.3
Objectives: This study measured the impact of shifts in maternal age and parity on the increase in the low birth weight (LBW) rate in Korea. Methods: We obtained raw data for all 6 397 945 live births registered at the Korea National Statistical Office between 1995 and 2005. We calculated the proportion of increment in the LBW rate due to changes in the distribution of maternal age and parity (AP-dis) and the proportion due to changes in the age- and parity-specific LBW rate (AP-spe). Results: The LBW rate increased from 3.02% in 1995 to 4.28% in 2005. The multiple birth rate increased from 1.32% to 2.19% during the same period. Of the 1.26% points increment in the LBW rate, 0.64% points occurred among singleton births and 0.62% points occurred among multiple births. Changes in the AP-dis accounted for 50% of the increase in the LBW rate among singleton births, but did not contribute to the increase in the LBW rate among multiple births. The remainder of the total increment in the LBW rate was explained by the increase in the AP-spe. Conclusions: This study demonstrated that shifts in maternal age and parity among singleton births and increased multiple births were important contributors to the increment in the LBW rate. This study also revealed that the increase in the AP-spe was an equally important contributor as the shifts in maternal age and parity to the increment in the LBW rate among singleton births and was a major contributor among multiple births.
Development and Evaluation of Genome-Probing Microarrays for Monitoring Lactic Acid Bacteria
Bae, Jin-Woo,Rhee, Sung-Keun,Park, Ja Ryeong,Chung, Won-Hyong,Nam, Young-Do,Lee, Insun,Kim, Hongik,Park, Yong-Ha American Society for Microbiology 2005 Applied and environmental microbiology Vol.71 No.12
<B>ABSTRACT</B><P>The genome-probing microarray (GPM) was developed for quantitative, high-throughput monitoring of community dynamics in lactic acid bacteria (LAB) fermentation through the deposit of 149 microbial genomes as probes on a glass slide. Compared to oligonucleotide microarrays, the specificity of GPM was remarkably increased to a species-specific level. GPM possesses about 10- to 100-fold higher sensitivity (2.5 ng of genomic DNA) than the currently used 50-mer oligonucleotide microarrays. Since signal variation between the different genomes was very low compared to that of cDNA or oligonucleotide-based microarrays, the capacity of global quantification of microbial genomes could also be observed in GPM hybridization. In order to assess the applicability of GPMs, LAB community dynamics were monitored during the fermentation of kimchi, a traditional Korean food. In this work, approximately 100 diverse LAB species could be quantitatively analyzed as actively involved in kimchi fermentation.</P>
Bae, Jin-Woo,Rhee, Sung-Keun,Nam, Young-Do,Park, Yong-Ha Oxford University Press 2005 Nucleic acids research Vol.33 No.13
<P>The generation of microarray probes with specificity below the species level is an ongoing challenge, not least because the high-throughput detection of microorganisms would be an efficient means of identifying environmentally relevant microbes. Here, we describe how suppression subtractive hybridization (SSH) can be applied to the production of microarray probes that are useful for microbial differentiation at the subspecies level. SSH was used to initially isolate unique genomic sequences of nine <I>Salmonella</I> strains, and these were validated in quadruplicate by microarray analysis. The results obtained indicate that a large group of genes subtracted by SSH could serve together, as one probe, for detecting a microbial subspecies. Similarly, the whole microbial genome (not subjected to SSH) can be used as a species-specific probe. The detailed methods described herein could be used and adapted for the estimation of any cultivable bacteria from different environments.</P>
( Sang Yun Ha ),( Yong-han Paik ),( Jung Wook Yang ),( Min Ju Lee ),( Hyunsik Bae ),( Cheol-keun Park ) 대한간학회 2016 Gut and Liver Vol.10 No.5
Background/Aims: Nicotinamide adenine dinucleotide phosphate oxidase (NOX)-mediated reactive oxygen species contribute to various liver diseases, including hepatocellular carcinoma (HCC). Uncertainties remain regarding the prognostic relevance of NOX1 and NOX4 protein expression in HCC. Methods: NOX1 and NOX4 protein expression was examined by using immunohistochemistry in tumor tissue from 227 HCC patients who underwent hepatectomy. Results: High immunoreactivity for NOX1 was observed in 197 (86.8%) of the 227 HCC cases and low immunoreactivity for NOX4 in 112 (49.3%). NOX1 and NOX4 proteins had opposite prognostic effects. High NOX1 expression was an independent predictor of both shorter recurrence-free survival (RFS) (p<0.01) and shorter overall survival (OS) (p=0.01). Low NOX4 expression was an independent predictor of both shorter RFS (p<0.01) and shorter OS (p=0.01). Subgroup analysis showed that, among patients with normal α-fetoprotein levels, patients with tumor size ≤5.0 cm and patients in Barcelona Clinic Liver Cancer stage A, high NOX1 expression had unfavorable effects on RFS, whereas low NOX4 expression had unfavorable effects on both RFS and OS. Conclusions: These findings demonstrated that NOX1 and NOX4 protein expression had opposite prognostic effects for HCC patients. Moreover, both proteins had prognostic value in HCC patients with normal α-fetoprotein levels or with early-stage HCC. (Gut Liver 2016;10:826-835)
Bae, Hyo-Kyung,Kim, Soo-Hyun,Lee, Sung-Young,Hwang, In-Sun,Park, Choon-Keun,Yang, Boo-Keun,Cheong, Hee-Tae The Korean Society of Animal Reproduction 2013 Reproductive & developmental biology Vol.37 No.1
The present study was conducted to examine the effect of antioxidant treatment during parthenogenetic activation procedure on the reactive oxygen species (ROS) levels and in vitro development of porcine parthenogenetic embryos. Porcine in vitro matured oocytes were activated by a combination of electric stimulus and 2 mM 6-dimethylaminopurine (6-DAMP) before in vitro culture. During the activation period, oocytes were treated with $50{\mu}M$ ${\beta}$-mercaptoethanol (${\beta}$-ME), $100{\mu}M$ L-ascorbic acid (Vit. C) or $100{\mu}M$ L-glutathione (GSH). To examine the ROS level, porcine parthenogenetic embryos were stained in $10{\mu}M$ dichlorohydrofluorescein diacetate ($H_2DCFDA$) dye 20 h after culture, examined under a fluorescence microscope, and the fluorescence intensity (pixels) were analyzed in each embryo. The parthenogenetic embryos were cultured for 6 days to evaluate the in vitro development. The apoptosis was measured by TUNEL assay. The $H_2O_2$ levels of parthenogenetic embryos were significantly lower in antioxidant treatment groups ($26.9{\pm}1.6{\sim}29.1{\pm}1.3$ pixels/embryo, p<0.05) compared to control ($33.2{\pm}1.7$ pixels/embryo). The development rate to the blastocyst stage was increased in antioxidant treatment groups (32.0~32.5%) compared to control (26.9%, p<0.05), although, there was no difference in apoptosis among groups. The result suggests that antioxidant treatment during parthenogenetic activation procedure can inhibit the ROS generation and enhance the in vitro development of porcine parthenogenetic embryos.
A First Order Digital Phase Locked Loop Having Linear Characteristic
Bae, Keun-Sung 경북대학교 공과대학 1982 工大硏究誌 Vol.11 No.-
時間誤差 檢山器(TED)를 사용한 새로운 形態의 디지틀 位相固定回路(DPLL)를 提案 解析하였다. 本 論文에서 考案된 TED는 線形的인 特性을 가지므로 DPLL의 動作은 線形 差分 方程式에 의해서 해석된다. 雜音이 存在하지 않을 때, 誘導된 方程式을 解析하여 제안된 DPLL이 入力信號의 位相과 周波數를 구했으며, 또한 빠른 收斂時間과 넓은 周波數 追跡範圍를 얻을 수 있는 最適條件 을 찾아내었다.