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Antibacterial Principles from Myristica fragrans Seeds
Avinash S. Dhake,Balasubramanian Narasimhan 한국식품영양과학회 2006 Journal of medicinal food Vol.9 No.3
Nutmeg (Myristica fragrans) is used in food preparations for its aromatic flavor. The present investigation wasundertaken to evaluate the antibacterial activity of constituents of M. fragransseeds. Seeds of M. fragranswere powderedand extracted with chloroform to obtain trimyristin, which on saponification yielded myristic acid. The mother liquor re-maining after separation of trimyristin was concentrated and column-chromatographed with petroleum ether to separate myris-ticin. Antibacterial activity of these isolated constituents was evaluated by determination of minimum inhibitory concentra-tion against selected Gram-positive and Gram-negative organisms. All the constituents isolated from nutmeg exhibited goodantibacterial activity. This study shows the potential of natural compounds in replacement of synthetic preservatives.
A Review on Herbal Antiasthmatics
Ravindra G. Mali,Avinash S. Dhake 경희대학교 융합한의과학연구소 2011 Oriental Pharmacy and Experimental Medicine Vol.11 No.2
In traditional systems of medicine, many plants have been documented to be useful for the treatment of various respiratory disorders including asthma. In the last two decades the use of medicinal plants and natural products has been increased dramatically all over the world. Current synthetic drugs used in pharmacotherapy of asthma are unable to act at all the stages and targets of asthma. However some herbal alternatives employed in asthma are proven to provide symptomatic relief and assist in the inhibition of disease progression also. The herbs have shown interesting results in various target specific biological activities such as bronchodilation, mast cell stabilization,anti-anaphylactic, anti-inflammatory, anti-spasmodic,anti-allergic, immunomodulatory and inhibition of mediators such as leukotrienes, lipoxygenase, cyclooxygenase,platelet activating, phosphodiesterase and cytokine, in the treatment of asthma. This paper is an attempt to classify these pharmacological and clinical findings based on their possible mechanism of action reported. It also signifies the need for development of polyherbal formulations containing various herbs acting at particular sites of the pathophysiological cascade of asthma for prophylaxis as well as for the treatment of asthma.
Bauhinia variegata Linn. (Mountain Ebony): a review on ethnobotany, phytochemistry and pharmacology
Mali, Ravindra G,Dhake, Avinash S Kyung Hee Oriental Medicine Research Center 2009 Oriental pharmacy and experimental medicine Vol.9 No.3
Bauhinia variegata Linn (Mountain Ebony) is a medium-sized, deciduous tree, found throughout India, ascending to an altitude of 1,300 m in the Himalayas. The plant is widely used by the tribals throughout India and popular in various indigenous systems of medicine like Ayurveda, Unani and Homoeopathy. Following the various traditional claims on utility of this plant in curing number of diseases, considerable efforts have been made by researchers to verify its utility through pharmacological screenings. The notable biological activities reported are anthelmintic, antiulcer, antitumour, antimicrobial, anti-inflammatory, antigoitrogenic, hepatoprotective and haemagglutination. Industrially, the plant is widely used for the manufacture of wood wool board, production of tannin, oil, gum and fibre. The plant is also utilized for afforestation to conserve the nature. In this article, a comprehensive account of the cultivation, microscopy, phytochemical investigation, traditional and biologically evaluated medicinal uses of B variegata is presented.
Bauhinia variegata Linn. (Mountain Ebony): a review on ethnobotany, phytochemistry and pharmacology
Ravindra G Mali,Avinash S Dhake 경희대학교 융합한의과학연구소 2009 Oriental Pharmacy and Experimental Medicine Vol.9 No.3
Bauhinia variegata Linn (Mountain Ebony) is a medium-sized, deciduous tree, found throughout India, ascending to an altitude of 1,300 m in the Himalayas. The plant is widely used by the tribals throughout India and popular in various indigenous systems of medicine like Ayurveda, Unani and Homoeopathy. Following the various traditional claims on utility of this plant in curing number of diseases, considerable efforts have been made by researchers to verify its utility through pharmacological screenings. The notable biological activities reported are anthelmintic, antiulcer, antitumour, antimicrobial, anti-inflammatory, antigoitrogenic, hepatoprotective and haemagglutination. Industrially, the plant is widely used for the manufacture of wood wool board, production of tannin, oil, gum and fibre. The plant is also utilized for afforestation to conserve the nature. In this article, a comprehensive account of the cultivation, microscopy, phytochemical investigation, traditional and biologically evaluated medicinal uses of B variegata is presented. Bauhinia variegata Linn (Mountain Ebony) is a medium-sized, deciduous tree, found throughout India, ascending to an altitude of 1,300 m in the Himalayas. The plant is widely used by the tribals throughout India and popular in various indigenous systems of medicine like Ayurveda, Unani and Homoeopathy. Following the various traditional claims on utility of this plant in curing number of diseases, considerable efforts have been made by researchers to verify its utility through pharmacological screenings. The notable biological activities reported are anthelmintic, antiulcer, antitumour, antimicrobial, anti-inflammatory, antigoitrogenic, hepatoprotective and haemagglutination. Industrially, the plant is widely used for the manufacture of wood wool board, production of tannin, oil, gum and fibre. The plant is also utilized for afforestation to conserve the nature. In this article, a comprehensive account of the cultivation, microscopy, phytochemical investigation, traditional and biologically evaluated medicinal uses of B variegata is presented.
A review on herbal antiasthmatics
Mali, Ravindra G.,Dhake, Avinash S. 경희한의학연구센터 2011 Oriental Pharmacy and Experimental Medicine Vol.11 No.2
In traditional systems of medicine, many plants have been documented to be useful for the treatment of various respiratory disorders including asthma. In the last two decades the use of medicinal plants and natural products has been increased dramatically all over the world. Current synthetic drugs used in pharmacotherapy of asthma are unable to act at all the stages and targets of asthma. However some herbal alternatives employed in asthma are proven to provide symptomatic relief and assist in the inhibition of disease progression also. The herbs have shown interesting results in various target specific biological activities such as bronchodilation, mast cell stabilization, anti-anaphylactic, anti-inflammatory, anti-spasmodic, anti-allergic, immunomodulatory and inhibition of mediators such as leukotrienes, lipoxygenase, cyclooxygenase, platelet activating, phosphodiesterase and cytokine, in the treatment of asthma. This paper is an attempt to classify these pharmacological and clinical findings based on their possible mechanism of action reported. It also signifies the need for development of polyherbal formulations containing various herbs acting at particular sites of the pathophysiological cascade of asthma for prophylaxis as well as for the treatment of asthma.