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      • KCI등재

        Vulnerability Assessment of the Critical Infrastructure against Man-Made Threats

        Gholamreza Jalali Farahani,Mohammad Hassan Ataee Kachoee,Mohammad Ali Ataee Kachoee 대한산업공학회 2018 Industrial Engineeering & Management Systems Vol.17 No.1

        Civilian airport is currently considered as one of the valuable assets of any country in the world and is considered as air boundaries; and have a great importance, so that any malfunctions or affair comprise to their body, will cause to the enormous material and moral damages and taking steps to reduce their vulnerability against threats, it will be essential and indispensable. What this study has been investigated is vulnerability assessment civilian airport against Man-made threats based on principles and the principles of passive defense. existence research is Applied (developmental) and analytical method - evaluative and evaluated by using FEMA techniques and individual vulnerability of key assets AHP Airport and went on to enumerate several factors which increase their vulnerability and qualitative analysis to provide solutions to reduce vulnerability. The vulnerability of airport key assets against hard, semi-hard, soft and special threats reckon quantitatively evaluated that based on the results from the opinions of experts The most vulnerabilities assets passenger terminal and car parking, Channel installations, office buildings, hangars for repairs and servicing of the systems, protective buildings, water tanks and water treatment pavilion for ceremonies are against special threats, assess Fueling area, Building Ground Safety (Fire), flight control tower building, Specialized equipment and bonded warehouses, Taxi and apron are against hard threats, assets installations for power stations and navigation equipment (radar), are against semi-hard threats, the asset approach control tower equipment against soft threat. And continuing investigation each of the above asset quality vulnerabilities was investigated.

      • Low Expression of the bcl2 Gene in Gastric Adenocarcinomas in Mazandaran Province of Iran

        Mirmajidi, Seyedeh Habibeh,Ataee, Ramin,Barzegar, Ali,Nikbakhsh, Novin,Shaterpour, Mohammad Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

        Background: Gastric cancer accounts for about 8% of the total cancer cases and 10% of total cancer deaths worldwide. It is the second lethal cancer after esophageal cancer and is considered the fourth most common cancer in north and northwest Iran. The bcl2 family has a key role in the regulation of apoptosis and change in its expression can contribute to cancer. This study initially scheduled to determine the expression of bcl2 gene in tissue samples of adenocarcinoma cancer patients. Materials and Methods: A total of 10 samples of gastric adenocarcinoma and 10 of normal tissues from Sari hospital were selected and after DNA extraction from tissues, bcl2 gene expression assayed by real-time PCR. Results: Our results demonstrated higher expression of the bcl2 gene in control compared with cancer and marginal cancer tissues. Conclusions: On one hand BCL2 plays an important role as an oncogene to inhibit apoptosis; on the other hand, it can initiate cell cycle arrest at G0 stage. Our observed association between its expression and patient survival is quite conflicting and may be tissue-specific. The data suggest expression both tumoural and non-tumoral(marginal) groups have lowered expression than controls (P>0.05). Due to the low number of samples we could not examine the relationship with clinicopathological features. However, bcl-2 expression may be important for prognostic outcome or a useful target for therapeutic intervention.

      • SCIESCOPUSKCI등재

        Cow`s Milk Allergy among Children with Gastroesophageal Reflux Disease

        ( Fatemeh Farahmand ),( Mehri Najafi ),( Pedram Ataee ),( Vajiheh Modarresi ),( Turan Shahraki ),( Nima Rezaei ) 대한소화기기능성질환·운동학회 2011 Gut and Liver Vol.5 No.3

        Background/Aims: Gastroesophageal reflux disease (GERD) and cow`s milk allergy (CMA) are two common conditions that occur in infancy. This study was performed to investigate the frequency of CMA in a group of patients with GERD. Methods: Eighty-one children with signs and symptoms of GERD were enrolled in this study. All subjects received omeprazole for 4 weeks after the initial evaluation. Empirical elimination of cow`s milk from the diet was started for the patients who did not respond to the omeprazole treatment. Results: Seventy-two cases presented with gastrointestinal signs and symptoms, whereas the remaining nine cases presented with respiratory complaints. After the initial treatment with omeprazole, two thirds of the cases (54 patients, 66.7%) responded well, and all of their symptoms were resolved. Cow`s milk was eliminated from the diets of the remaining 27 patients. All signs and symptoms of GERD were resolved in this group after a 4 week elimination of cow`s milk from the diet. Conclusions: A diagnosis of CMA was considered in one third of the pediatric cases with signs and symptoms of GERD. This finding shows that CMA can mimic or aggravate all signs and symptoms of severe GERD during infancy. (Gut Liver 2011;5:298-301)

      • SCOPUSKCI등재

        Effect of titanium and stainless steel posts in detection of vertical root fractures using NewTom VG cone beam computed tomography system

        Mohammadpour, Mahdis,Bakhshalian, Neema,Shahab, Shahriar,Sadeghi, Shaya,Ataee, Mona,Sarikhani, Soodeh Korean Academy of Oral and Maxillofacial Radiology 2014 Imaging Science in Dentistry Vol.44 No.2

        Purpose: Vertical root fracture (VRF) is a common complication in endodontically treated teeth. Considering the poor prognosis of VRF, a reliable and valid detection method is necessary. Cone beam computed tomography (CBCT) has been reported to be a reliable tool for the detection of VRF; however, the presence of metallic intracanal posts can decrease the diagnostic values of CBCT systems. This study evaluated and compared the effects of intracanal stainless steel or titanium posts on the sensitivity, specificity, and accuracy of VRF detection using a NewTom VG CBCT system. Materials and Methods: Eighty extracted single-rooted teeth were selected and sectioned at the cemento-enamel junction. The roots were divided into two groups of 40. Root fracture was induced in the test group by using an Instron machine, while the control group was kept intact. Roots were randomly embedded in acrylic blocks and radiographed with the NewTom VG, both with titanium and stainless steel posts and also without posts. Sensitivity, specificity, and accuracy values were calculated as compared to the gold standard. Results: The sensitivity, specificity, and accuracy of VRF diagnosis were significantly lower in teeth with stainless steel and titanium posts than in those without posts. Interobserver agreement was the highest in teeth without posts, followed by stainless steel posts, and then titanium posts. Conclusion: Intracanal posts significantly decreased the VRF diagnostic values of CBCT. The stainless steel posts decreased the diagnostic values more than the titanium posts.

      • KCI등재

        Curcumin Exerts Neuroprotective Effects Against Homocysteine Intracerebroventricular Injection-Induced Cognitive Impairment and Oxidative Stress in Rat Brain

        Amin Ataie,Masoumeh Sabetkasaei,Abbas Haghparast,Akbar Hajizadeh Moghaddam,Ramin Ataee,Shiva Nasiraei Moghaddam 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.4

        Aging is the major risk factor for neurodegenerative diseases and oxidative stress and is involved in their pathophysiology. Oxidative stress can induce neuronal damage and modulate intracellular signaling, ultimately leading to neuronal death by apoptosis or necrosis. In this study we investigated the neuroprotective properties of the natural polyphenolic antioxidant compound, curcumin, against homocysteine (Hcy) neurotoxicity. Curcumin (5, 15, or 45mg/kg) was injected intraperitoneally once daily for a period of 10 days beginning 5 days prior to Hcy (0.2μmol/μL) intracerebroventricular injection in rats. Biochemical and behavioral studies, including passive avoidance learning and locomotor activity tests, were evaluated 24 hours after the last injection of curcumin or vehicle. Results indicated that Hcy induces lipid peroxidation and increases malondialdehyde (MDA) and superoxide anion (SOA) levels in whole rat brain. In addition, Hcy impaired memory retention in the passive avoidance learning test. However, curcumin treatment significantly decreased MDA and SOA levels and improved learning and memory in rats. These results suggest that Hcy may induce lipid peroxidation in rat brain and that polyphenol treatment (curcumin) improves learning and memory deficits by protecting the nervous system against oxidative stress.

      • KCI등재후보

        Should all patients with hypertension be worried about developing severe coronavirus disease 2019 (COVID-19)?

        Bahardoust Mansour,Goharrizi Mohammad Ali Sheikh Beig,Bahardoust Mansour,Alvanegh Akbar Ghorbani,Ataee Mohammad Reza,Bagheri Mehdi,Navidiyan Ensiyeh Shabani,Zijoud Seyed Reza Hosseini,Heiat Mohammad 대한고혈압학회 2021 Clinical Hypertension Vol.27 No.2

        Background: Hypertension, the most common comorbidity among coronavirus disease 2019 (COVID-19) patients, is accompanied by worse clinical outcomes, but there is lack of evidence about prognostic factors among COVID19 patients with hypertension. We have come up with some prognostic factors to predict the severity of COVID-19 among hypertensive patients. In addition, epidemiologic, clinical and laboratory differences among COVID-19 patients with and without underlying hypertension were evaluated. Methods: Medical profiles of 598 COVID-19 cases were analyzed. Patients were divided into two comparative groups according to their positive or negative history of hypertension. Then, epidemiologic, clinical, laboratory and radiological features and also clinical outcomes were compared. Results: 176 (29.4%) patients had underlying hypertension. Diabetes was significantly higher in hypertensive group [72 (40.9%) vs 76 (18%)] (P-value: 0.001). Cardiovascular and renal disorders were significantly higher in hypertensive patients. (P-value: 0.001 and 0.013 respectively). In COVID-19 patients with hypertension, severe/critical types were significantly higher. [42(23.8%) vs. 41(9.7%)], (P-value: 0.012). In the logistic regression model, Body mass index > 25 (ORAdj: 1.8, 95% CI: 1.2 to 2.42; P-value: 0.027), age over 60 (ORAdj: 1.26, 95% CI: 1.08 to 1.42; P-value: 0.021), increased hospitalization period (ORAdj: 2.1, 95% CI: 1.24 to 2.97; P-value: 0.013), type 2 diabetes (ORAdj: 2.22, 95% CI: 1.15 to 3.31; P-value: 0.001) and chronic kidney disease (ORAdj: 1.83, 95% CI: 1.19 to 2.21; P-value: 0.013) were related with progression of COVID-19. Conclusion: Hypertensive patients with Age > 60-year-old, BMI > 25 Kg/m2 , CVD, diabetes and chronic kidney disease are associated with poor outcomes in those with COVID-19 infection.

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