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- 저자 : Asim Jilani (검색결과 2 건)
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Asim Jilani,Mohammad Omaish Ansari,Ghani ur Rehman,Muhammad Bilal Shakoor,Syed Zajif Hussain,Mohd Hafiz Dzarfan Othman,Sajid Rashid Ahmad,Mohsin Raza Dustgeer,Ahmed Alshahrie 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.109 No.-
The toxic and carcinogenic organic compounds discharge from industries, contaminate the natural reservoirsof water and air which eventually pose a global threat not only to the aquatic life but also to thehumanity. Herein, ternary nanocomposites of silver-nanoparticle (AgNPs)-decorated on polyaniline(Pani)-wrapped zinc oxide nanorods (AgNPs@Pani/ZnO) were prepared via a facile approach. Thenanocomposite degraded 97.91% phenol with an optimized dosage and concentration of H2O2. Moreover, the apparent rate constant for phenol degradation was 3.69 times higher than for pure ZnOnanorods. The hydrogen production from AgNPs@Pani/ZnO was 1.58 and 2.74 times higher than Pani/ZnO and ZnO, respectively. The enhanced phenol degradation and hydrogen production is attributed tothe transfer of holes to the Pani, from which the electrons were transferred to the conduction band ofZnO and eventually to the conduction band of the AgNPs, where they accelerated the redox reactionsfor rapid photolysis of water and phenol. The concentration of the catalyst dosage affected the rate ofphenol degradation. Further, response surface methodology was also applied in order to design 13 setsof random experiments in which the catalyst dosage and degradation time were varied to predict thephenol degradation.
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Mohammed Abbas,Mohammed Alkaff,Asim Jilani,Haneen Alsehli,Laila Damiati,Mamdooh Kotb,Moahmmed Abdelwahed,Fahad Alghamdi,Gauthaman Kalamegam 한국조직공학과 재생의학회 2018 조직공학과 재생의학 Vol.15 No.5
BACKGROUND: Mesenchymal stem cells (MSCs) and/or biological scaffolds have been used to regenerate articular cartilage with variable success. In the present study we evaluated cartilage regeneration using a combination of bone marrow (BM)-MSCs, HyalofastTM and/or native cartilage tissue following full thickness surgical cartilage defect in rabbits. METHODS: Full-thickness surgical ablation of the medial-tibial cartilage was performed in New Zealand white (NZW) rabbits. Control rabbits (Group-I) received no treatment; Animals in other groups were treated as follows. Group-II: BMMSCs (1 9 106 cells) ? HyalofastTM; Group-III: BMMSCs (1 9 106 cells) ? cartilage pellet (CP); and Group-IV: BMMSCs (1 9 106 cells) ? HyalofastTM ? CP. Animals were sacrificed at 12 weeks and cartilage regeneration analyzed using histopathology, International Cartilage Repair Society (ICRS-II) score, magnetic resonance observation of cartilage repair tissue (MOCART) score and biomechanical studies. RESULTS: Gross images showed good tissue repair (Groups IV[III[Group II) and histology demonstrated intact superficial layer, normal chondrocyte arrangement, tidemark and cartilage matrix staining (Groups III and IV) compared to the untreated control (Group I) respectively. ICRS-II score was 52.5, 65.0, 66 and 75% (Groups I–IV) and the MOCART score was 50.0, 73.75 and 76.25 (Groups II–IV) respectively. Biomechanical properties of the regenerated cartilage tissue in Group IV closed resembled that of a normal cartilage. CONCLUSION: HyalofastTM together with BM-MSCs and CP led to efficient cartilage regeneration following full thickness surgical ablation of tibial articular cartilage in vivo in rabbits. Presence of hyaluronic acid in the scaffold and native microenvironment cues probably facilitated differentiation and integration of BM-MSCs.
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