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Anika Tabassum,Muntasir Akash 국립중앙과학관 2022 Journal of Asia-Pacific Biodiversity Vol.15 No.2
The study represents a stomatopod crustacean, Clorida latreillei Eydoux & Souleyet, 1842 reported for the first time in Bangladesh. This new record was revealed through a cursory expedition to the Sundarbans mangrove coast. Photos of the collected specimen, diagnostic characteristics, and comments on the distribution are provided in this paper. Based on peer-reviewed literature, the article also provides the first annotated checklist of stomatopods of Bangladesh. Given the extent of the country’s maritime boundary and associated diverse habitats, stomatopods, commonly known as mantis shrimps, appear to be an understudied group as only eight species under two families are so far listed.
Anika Daing,Sarvendra Vikram Singh,Charanjeet Singh Saimbi,Mohammad Akhlaq Khan,Srikanta Kumar Rath 대한치주과학회 2012 Journal of Periodontal & Implant Science Vol.42 No.5
Purpose: Cyclooxygenase (COX) enzyme catalyzes the production of prostaglandins, which are important mediators of tissue destruction in periodontitis. Single nucleotide polymorphisms of COX2 enzyme have been associated with increasing susceptibility to inflammatory diseases. The present study evaluates the association of two single nucleotide polymorphisms in COX2 gene (-1195G>A and 8473C>T) with chronic periodontitis in North Indians. Methods: Both SNPs and their haplotypes were used to explore the associations between COX2 polymorphisms and chronic periodontitis in 56 patients and 60 controls. Genotyping was done by polymerase chain reaction followed by restriction fragment length polymorphism. Chi-square test and logistic regression analysis were performed for association analysis. Results: By the individual genotype analysis, mutant genotypes (GA and AA) of COX2 -1195 showed more than a two fold risk (odds ratio [OR]>2) and COX2 8473 (TC and CC) showed a reduced risk for the disease, but the findings were not statistically significant. Haplotype analysis showed that the frequency of the haplotype AT was higher in the case group and a significant association was found for haplotype AT (OR, 1.79; 95% confidence interval, 1.03 to 3.11; P=0.0370) indicating an association between the AT haplotype of COX2 gene SNPs and chronic periodontitis. Conclusions: Individual genotypes of both the SNPs were not associated while haplotype AT was found to be associated with chronic periodontitis in North Indians.
Daing, Anika,Singh, Sarvendra Vikram,Saimbi, Charanjeet Singh,Khan, Mohammad Akhlaq,Rath, Srikanta Kumar Korean Academy of Periodontology 2012 Journal of Periodontal & Implant Science Vol.42 No.5
Purpose: Cyclooxygenase (COX) enzyme catalyzes the production of prostaglandins, which are important mediators of tissue destruction in periodontitis. Single nucleotide polymorphisms of $COX_2$ enzyme have been associated with increasing susceptibility to inflammatory diseases. The present study evaluates the association of two single nucleotide polymorphisms in $COX_2$ gene (-1195G>A and $8_{473}$C>T) with chronic periodontitis in North Indians. Methods: Both SNPs and their haplotypes were used to explore the associations between $COX_2$ polymorphisms and chronic periodontitis in 56 patients and 60 controls. Genotyping was done by polymerase chain reaction followed by restriction fragment length polymorphism. Chi-square test and logistic regression analysis were performed for association analysis. Results: By the individual genotype analysis, mutant genotypes (GA and AA) of $COX_2$-1195 showed more than a two fold risk (odds ratio [OR]>2) and $COX_2$ $8_{473}$ (TC and CC) showed a reduced risk for the disease, but the findings were not statistically significant. Haplotype analysis showed that the frequency of the haplotype AT was higher in the case group and a significant association was found for haplotype AT (OR, 1.79; 95% confidence interval, 1.03 to 3.11; P=0.0370) indicating an association between the AT haplotype of $COX_2$ gene SNPs and chronic periodontitis. Conclusions: Individual genotypes of both the SNPs were not associated while haplotype AT was found to be associated with chronic periodontitis in North Indians.
CCL2 Chemokine as a Potential Biomarker for Prostate Cancer: A Pilot Study
Igor Tsaur,Anika Noack,Jasmina Makarevic,Elsie Oppermann,Ana Maria Waaga-Gasser,Martin Gasser,Hendrik Borgmann,Tanja Huesch,Kilian M. Gust,Michael Reiter,David Schilling,Georg Bartsch,Axel Haferkamp,R 대한암학회 2015 Cancer Research and Treatment Vol.47 No.2
Purpose Prostate specific antigen is not reliable in diagnosing prostate cancer (PCa), making theidentification of novel, precise diagnostic biomarkers important. Since chemokines areassociated with more aggressive disease and poor prognosis in diverse malignancies, weaimed to investigate the diagnostic relevance of chemokines in PCa. Materials and MethodsPreoperative and early postoperative serum samples were obtained from 39 consecutivePCa patients undergoing radical prostatectomy. Serum from 15 healthy volunteers servedas controls. Concentrations of CXCL12, CXCL13, CX3CL1, CCL2, CCL5, and CCL20 weremeasured in serum by Luminex. The expression activity of CXCR3, CXCR4, CXCR5, CXCR7,CXCL12, CXCL13, CX3CR1, CXCL1, CCR2, CCR5, CCR6, CCR7, CCL2, and CCL5 mRNA wasassessed in tumor and adjacent normal tissue of prostatectomy specimens by quantitativereal-time polymerase chain reaction. The associations of these chemokines with clinicaland histological parameters were tested. ResultsThe gene expression activity of CCL2 and CCR6 was significantly higher in tumor tissuecompared to adjacent normal tissue. CCL2 was also significantly higher in the blood samplesof PCa patients, compared to controls. CCL5, CCL20, and CX3CL1 were lower in patientserum, compared to controls. CCR2 tissue mRNA was negatively correlated with the Gleasonscore and grading. ConclusionChemokines are significantly modified during tumorigenesis of PCa, and CCL2 is a promisingdiagnostic biomarker.
Priyanka Thakur,Anika,Rajat Suhag,Atul Dhiman,Satish Kumar 한국식품과학회 2024 Food Science and Biotechnology Vol.33 No.4
Black carrots are a type of carrot that is naturally dark purple or black in color. They are a good source of antioxidants, vitamins, and minerals, and have been shown to have several health benefits, including reducing the risk of cancer, heart disease, and diabetes. This review article discusses the bioactive compounds present in black carrot, including anthocyanins, phenolic acids, carotenoids, and organic acids and sugars. It also compares the bioactive compounds and antioxidant capacity of black carrot with other carrot varieties. Furthermore, it discusses various postharvest processing methods, both conventional and novel, such as encapsulation, drying, and microbial decontamination, highlighting their effects on preserving and stabilizing the bioactive compounds. The review also emphasizes the incorporation of black carrot into different food products, including dairy items, beverages, and baked goods, and their impact on nutritional enhancement. The article provides knowledge on utilizing black carrot for improved nutritional and functional outcomes.
Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis
Balaram Krishna J Hanumanthu,Anika Sasidharan Nair,Adarsh Katamreddy,Jason S Gilbert,Jee Young You,Obiageli Lynda Offor,Ankit Kushwaha,Ankita Krishnan,Marzio Napolitano,Leonidas Palaidimos,Joaquin Mor 대한중환자의학회 2021 Acute and Critical Care Vol.36 No.3
Background Patients with sepsis are at risk for developing sepsis-induced cardiomyopathy (SIC). Previous studies offer inconsistent results regarding the association of SIC and mortality. This study sought to assess whether SIC is linked to mortality in patients with sepsis and to evaluate predictors of the development of SIC. Methods In this retrospective study, patients admitted to the medical intensive care unit with a diagnosis of sepsis in the absence of acute coronary syndrome were included. SIC was identified using transthoracic echo and was defined by a new onset decline in left ventricular ejection fraction (LVEF) ≤50%, or ≥10% decline in LVEF compared to baseline in patients with a history of heart failure with reduced ejection fraction. Multivariable logistic regression analysis was performed using the R software program. Results Of the 359 patients in the final analysis, 19 (5.3%) had SIC. Eight (42.1%) of the 19 patients in the SIC group and 60 (17.6%) of the 340 patients in the non-SIC group died during hospitalization. SIC was associated with an increased risk for all-cause in-hospital mortality (odds ratio [OR], 4.46; 95% confidence interval [CI], 1.15–18.69; P=0.03). Independent predictors for the development of SIC were albumin level (OR, 0.47; 95% CI, 0.23–0.93; P=0.03) and culture positivity (OR, 8.47; 95% CI, 2.24–55.61; P=0.006). Concomitant right ventricular hypokinesis was noted in 13 (68.4%) of the 19 SIC patients. Conclusions SIC was associated with an increased risk for all-cause in-hospital mortality. Low albumin level and culture positivity were independent predictors of SIC.
Salim Azad,Abdus Subhan Mollick,Firuz Anika Setu,Nabiul Islam Khan,Kamruzzaman 국립중앙과학관 2022 Journal of Asia-Pacific Biodiversity Vol.15 No.3
Stand structure, diversity, and plasticity of leaf morphology of Xylocarpus mekongensis were investigated among saline zones in Bangladesh Sundarbans. Stand structure and species diversity were assessed in 27 sample plots (20 m 20 m) covering 1.08 ha of forest. A total of 11 species were recorded. Out of them, 7, 6, and 9 species were found in fresh water, moderate, and strong saline zone, respectively. Species dominance in terms of importance value showed Heritiera fomes > Excoecaria agallocha > Bruguiera sexangula > Xylocarpus mekongensis in fresh water zone; H. fomes > E. agallocha > Avicennia officinalis > Ceriops decandra in moderate saline zone. E. agallocha > Sonneratia apetala > H. fomes > C. decandra in strong saline zone. Species diversity decreased from fresh water to strong saline zone. The findings showed a wide range of leaf morphological plasticity of all the parameters within and among saline zones. Leaf index, plasticity index, and specific leaf area were maximum in fresh water zone than of others. The findings of PCA revealed clear evidences of plastic behavior of leaf morphological parameters. Thus, the plasticity of leaf morphology might contribute as an influential biological signs of forthcoming climate change events.