Organizational Change as Student Project

( Anette Oxenswardh(phd) ),( Maria Fredriksson(phd) ) 한국품질경영학회 2015 한국품질경영학회 학술대회 Vol.2015 No.2

Purpose - This research project aims to study how some organizations choose to prioritize certain changes when offered assistance by students who are studying Quality Technology. Method - A literature study is pursued. In this project, textual analysis of student works as reports, project diaries, subtasks etc. are used as empirical sources. Findings - Organizations seem to already have identified areas for changes, but they do have neither the methods and proper tools nor the knowhow of implementing the changes. The results show that organizations take their opportunity to learn different tools in quality technology pointed out and used by students. There seems to be a huge need of knowledge about different tools and help with implementation of organizational changes. Practical Implications - The major implication of the study is that managers in organizations are positive in using university students in organizational change. Also the students fill the gap for needs of knowledge about implementation. However, it is the managers together with the students who suggest change project and the students continue to perform the change. Originality/Value of paper - The study makes a contribution to the knowledge of Change Management in exploring how educational course can bridge the gap between theoretical and practical aspects of organizational change by creating collaborative learning.

Numerical Simulation of Displacement Instabilities of Surface Grooves on an Alumina Forming Alloy during Thermal Cycling Oxidation

Ding Jun,Anette M. Karlsson,K.J. Kang 대한기계학회 2007 대한기계학회 춘추학술대회 Vol.2007 No.10

Displacement instability of the thermally grown oxide (TGO) is a fundamental source of failure in some thermal barrier systems. In this work, a finite element analysis has been performed to simulate the displacement instability occurred at a heat resistant metal with superficial TGO exposed to thermal cycling. Lateral and in-plane growth of the TGO which happen during high temperature are also simulated by means of material property change from the substrate metal to the TGO. Assumptions and referring about the material properties are minimized for rigorous reality. Most of the material properties including the TGO growth are based on the experimental results obtained in-house. Good agreement with the experimental observations proves the accuracy and validity of this simulation, which will be useful for future works on more complicated phenomena such as deformation under thermo-mechanical cycling.

Enhancement of Human Adaptive Immune Responses by Administration of a High-Molecular-Weight Polysaccharide Extract from the Cyanobacterium Arthrospira platensis

Morten Løbner,Anette Walsted,Rune Larsen,Klaus Bendtzen,Claus Henrik Nielsen 한국식품영양과학회 2008 Journal of medicinal food Vol.11 No.2

The effect of consumption of Immulina, a high-molecular-weight polysaccharide extract from the cyanobac-terium Arthrospira platensis, on adaptive immune responses was investigated by evaluation of changes in leukocyte respon-siveness to two foreign recall antigens, Candida albicans(CA) and tetanus toxoid (TT), in vitro. Consumption of Immulinaby 11 healthy male volunteers caused an immediate, but temporary, increase of CA-induced CD4. T-helper (Th) cell pro-liferation (P. .02). TT-induced Th cell proliferation was increased in individuals over 50 years of age (P. .05) and corre-lated with age (P. .02). Consumption for 8 days enhanced the CA-induced B cell proliferation (P. .02), but after 56 daysa diminution was seen (P. .03). The CA-elicited production of the Th1 cytokines tumor necrosis factor (TNF)-., interleukin(IL)-2, and interferon (IFN)-. was increased after Immunlina administration for 3 days (P. .001,. .03, and. .007, re-spectively), and increased IL-2 production persisted after 56 days (P. .004). The TNF-., IFN-., and IL-6 responses to TTwere enhanced after 8 and 14 days (P. .002.05), while IL-5 responses increased significantly within 3 days (P. .04) andfell below baseline levels after 14 days (P. .008). Conversely, consumption for 3 days inhibited the IL-4 responses to bothCA and TT (P. .008 and P. .03, respectively). No effects on IL-10 responses were observed. Upon addition to normalmononuclear cells in vitro, Immulina elicited strong TNF-., IL-1., and IL-6 responses, indicating that it acts by inducing apro-inflammatory state. Taken together, the data suggest that Immulina causes an age-dependent, temporary enhancement ofadaptive immune responses.

Pooled Analysis of the Cow’s Milk-related-Symptom-Score (CoMiSSTM) as a Predictor for Cow’s Milk Related Symptoms

Yvan Vandenplas,Philippe Steenhout,Anette Järvi,Anne-Sophie Garreau,Rajat Mukherjee 대한소아소화기영양학회 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.1

Purpose: The diagnosis of cow’s milk (CM) allergy is a challenge. The Cow’s Milk-related-Symptom-Score (CoMiSSTM) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the CoMiSSTM was evaluated in three clinical trials. Methods: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 chal-lenge test on the month-1 CoMiSSTM, adjusting for baseline CoMiSSTM using a logistic regression model. In addition a logistic regression model was also fitted to the month-1 challenge test result with the change in CoMiSSTM from baseline as a predictor. Results: Results suggest that infants having a low CoMiSSTM (median, 5) after 1 month dietary treatment free from intact CM protein have a significant risk of having a positive challenge test (odds ratio, 0.83; 95% confidence interval, 0.75-0.93; p=0.002). Pooled data suggest that the change in CoMiSSTM from baseline to month-1 can predict CM related symptoms as a confirmed diagnosis according to the challenge test at month-1. However, in order to validate such a tool, infants without CM related symptoms would also need to be enrolled in a validation trial. A concern is that it may not be ethical to expose healthy infants to a therapeutic formula and a challenge test.Conclusion: Pooled data analysis emphasizes that the CoMiSSTM has the potential to be of interest in infants sus-pected to have CM-related-symptoms. A prospective validation trial is needed.

Numerical Analysis for the Evolution of Surface Morphology of an Alumina Forming Alloy during Thermal-Mechanical Cycling

Ding Jun,F.X. Li,Anette M. Karlsson,Ki-Ju Kang 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.5

Morphology change in surface grooves embedded in the TGO forming material substrate is a fundamental source of failure in some thermal barrier systems. In this work, the morphology instabilities on Fecralloy substrate due to the thermal-mechanical loading cycles has been explored with the variation of mechanical load. Assumptions and referring about the material properties are minimized for rigorous reality. Most of the material properties including TGO growth are based on the results experimentally obtained in-house. Employed on the finite element procedures developed by ourselves, the effects of creep of TGO and substrate on the morphology of surface grooves have been investigated. Comparison made between presence of creep and absence of creep consideration in finite element analysis shows that the creep deformation plays a central role in the displacement instabilities of TGO under thermal-mechanical loading cycles especially for the case of the relatively small magnitude of mechanical loading.

Pooled Analysis of the Cow's Milk-related-Symptom-Score (CoMiSS^TM) as a Predictor for Cow's Milk Related Symptoms

Vandenplas, Yvan,Steenhout, Philippe,Jarvi, Anette,Garreau, Anne-Sophie,Mukherjee, Rajat The Korean Society of Pediatric Gastroenterology 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.1

Purpose: The diagnosis of cow's milk (CM) allergy is a challenge. The Cow's Milk-related-Symptom-Score ($CoMiSS^{TM}$) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the $CoMiSS^{TM}$ was evaluated in three clinical trials. Methods: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 challenge test on the month-1 $CoMiSS^{TM}$, adjusting for baseline $CoMiSS^{TM}$ using a logistic regression model. In addition a logistic regression model was also fitted to the month-1 challenge test result with the change in $CoMiSS^{TM}$ from baseline as a predictor. Results: Results suggest that infants having a low $CoMiSS^{TM}$ (median, 5) after 1 month dietary treatment free from intact CM protein have a significant risk of having a positive challenge test (odds ratio, 0.83; 95% confidence interval, 0.75-0.93; p=0.002). Pooled data suggest that the change in $CoMiSS^{TM}$ from baseline to month-1 can predict CM related symptoms as a confirmed diagnosis according to the challenge test at month-1. However, in order to validate such a tool, infants without CM related symptoms would also need to be enrolled in a validation trial. A concern is that it may not be ethical to expose healthy infants to a therapeutic formula and a challenge test. Conclusion: Pooled data analysis emphasizes that the $CoMiSS^{TM}$ has the potential to be of interest in infants suspected to have CM-related-symptoms. A prospective validation trial is needed.

Applying microscopic analytic techniques for failure analysis in electronic assemblies

Otto Grosshardt,Boldizsár Árpád Nagy,Anette Laetsch 한국현미경학회 2019 Applied microscopy Vol.49 No.3

The present paper gives an overview of surface failures, internal nonconformities and solders joint failures detected by microscopic analysis of electronic assemblies. Optical microscopy (stereomicroscopy) and Fourier-Transform-Infrared (FTIR) microscopy is used for documentation and failure localization on electronic samples surface. For internal observable conditions a metallographic cross-section analysis of the sample is required. The aim of this work is to present some internal and external observable nonconformities which frequently appear in electronic assemblies. In order to detect these nonconformities, optical microscopy, cross section analysis, FTIR-microscopy and scanning electron microscopy with energy dispersive spectrometry (SEM-EDS) were used as analytical techniques.

Microstructural evolution of carbon nanotube fibers: deformation and strength mechanism.

Liu, Xia,Lu, Weibang,Ayala, Orlando M,Wang, Lian-Ping,Karlsson, Anette M,Yang, Qingsheng,Chou, Tsu-Wei RSC Pub 2013 Nanoscale Vol.5 No.5

<P>A comprehensive investigation of the mechanical behavior and microstructural evolution of carbon nanotube (CNT) continuous fibers under twisting and tension is conducted using coarse-grained molecular dynamics simulations. The tensile strength of CNT fibers with random CNT stacking is found to be higher than that of fibers with regular CNT stacking. The factor dominating the mechanical response of CNT fibers is identified as individual CNT stretching. A simplified twisted CNT fiber model is studied to illustrate the structural evolution mechanisms of CNT fibers under tension. Moreover, it is demonstrated that CNT fibers can be reinforced by enhancing intertube interactions. This study would be helpful not only in the general understanding of the nano- and micro-scale factors affecting CNT fibers' mechanical behavior, but also in the optimal design of CNT fibers' architecture and performance.</P>

Growth in Infants with Cow's Milk Protein Allergy Fed an Amino Acid-Based Formula

Vandenplas, Yvan,Dupont, Christophe,Eigenmann, Philippe,Heine, Ralf G.,Host, Arne,Jarvi, Anette,Kuitunen, Mikael,Mukherjee, Rajat,Ribes-Koninckx, Carmen,Szajewska, Hania,Berg, Andrea von,Zhao, Zheng-Y The Korean Society of Pediatric Gastroenterology 2021 Pediatric gastroenterology, hepatology & nutrition Vol.24 No.4

Purpose: The present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA). Methods: Non-breastfed, term infants aged 0-6 months with symptoms suggestive of CMPA were recruited from 10 pediatric centers in China. After enrollment, infants were started on AAF for two weeks, followed by an open food challenge (OFC) with cow's milk-based formula (CMF). Infants with confirmed CMPA remained on AAF until 9 months of age, in conjunction with a cow's milk protein-free complementary diet. Body weight, length, and head circumference were measured at enrollment and 9 months of age. Measurements were converted to weight-for-age, length-for-age, and head circumference-for-age Z scores (WAZ, LAZ, HCAZ), based on the World Health Organization growth reference. Results: Of 254 infants (median age 16.1 weeks, 50.9% male), 218 (85.8%) were diagnosed with non-IgE-mediated CMPA, 33 (13.0%) tolerated CMF, and 3 (1.2%) did not complete the OFC. The mean WAZ decreased from 0.119 to -0.029 between birth and enrollment (p=0.067), with significant catch-up growth to 0.178 at 9 months of age (p=0.012) while being fed the AAF. There were no significant changes in LAZ (0.400 vs. 0.552; p=0.214) or HCAZ (-0.356 vs. -0.284; p=0.705) from the time of enrollment to age 9 months, suggesting normal linear and head growth velocity. Conclusion: The amino acid-based study formula, in conjunction with a cow's milk proteinfree complementary diet, supported normal growth till 9 months of age in a cohort of Chinese infants with challenge-confirmed non-IgE-mediated CMPA.

Isotopic signatures of N2O produced by ammonia-oxidizing archaea from soils.

Jung, Man-Young,Well, Reinhard,Min, Deullae,Giesemann, Anette,Park, Soo-Je,Kim, Jong-Geol,Kim, So-Jeong,Rhee, Sung-Keun Nature Publishing Group 2014 The ISME journal Vol.8 No.5

<P>N2O gas is involved in global warming and ozone depletion. The major sources of N2O are soil microbial processes. Anthropogenic inputs into the nitrogen cycle have exacerbated these microbial processes, including nitrification. Ammonia-oxidizing archaea (AOA) are major members of the pool of soil ammonia-oxidizing microorganisms. This study investigated the isotopic signatures of N2O produced by soil AOA and associated N2O production processes. All five AOA strains (I.1a, I.1a-associated and I.1b clades of Thaumarchaeota) from soil produced N2O and their yields were comparable to those of ammonia-oxidizing bacteria (AOB). The levels of site preference (SP), δ(15)N(bulk) and δ(18)O -N2O of soil AOA strains were 13-30%, -13 to -35% and 22-36%, respectively, and strains MY1-3 and other soil AOA strains had distinct isotopic signatures. A (15)N-NH4(+)-labeling experiment indicated that N2O originated from two different production pathways (that is, ammonia oxidation and nitrifier denitrification), which suggests that the isotopic signatures of N2O from AOA may be attributable to the relative contributions of these two processes. The highest N2O production yield and lowest site preference of acidophilic strain CS may be related to enhanced nitrifier denitrification for detoxifying nitrite. Previously, it was not possible to detect N2O from soil AOA because of similarities between its isotopic signatures and those from AOB. Given the predominance of AOA over AOB in most soils, a significant proportion of the total N2O emissions from soil nitrification may be attributable to AOA.</P>