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Rheological behavior of blood in Wistar rats with different total cholesterol levels
Medina-Torres Luis,Calderas Fausto,Calderas Fausto,Núñez–Ramírez Diola-Marina,Castro Andrés Navarrete,Bernad-Bernad Ma. Josefa,Manero Octavio 한국유변학회 2022 Korea-Australia rheology journal Vol.34 No.4
Blood is a rheologically complex suspension, in which the soluble fraction contains proteins, total cholesterol and triglycerides. The blood rheological behavior is strongly affected by the concentration of these components. This work evaluates the total cholesterol effect on the rheological behavior of Wistar rat blood by means of an in vitro study. Twenty-one rats were divided into 3 groups, each one had an assigned diet with different fat content: reference group (RG) with 3%, medium fat content group (MG) with 4.5% and high-fat content group (HG) with 6.5%; in the latter group, mixed-vegetable fat was added. From each group, intraocular representative blood samples were taken with time lapse of 15 days between each sampling followed by biochemical and hemo-rheological tests. The first analysis detected changes in total cholesterol levels, attributed to the rat metabolism, formation of adipose tissue and competition for food. The second test consisted in steady simple-shear and linear oscillatory flow. The linear viscoelastic spectra reveal that the viscous modulus is larger than the elastic modulus (G > G′), with simple-shear viscosity exhibiting shear-thinning behavior. An important finding is a pseudo-solid- like behavior at low frequencies (1 rad/s) akin to the presence of yield stresses in the high-fat content group after 30 days, revealing strong interactions between total cholesterol levels and blood cells. The hemo-rheological tests represent a promising alternative to identify pathologies present in the blood (total cholesterol, digestive problems, and diabetes).
Named Entity Recognition in Electronic Health Records: A Methodological Review
María C. Durango,Ever A. Torres-Silva,Andrés Orozco-Duque 대한의료정보학회 2023 Healthcare Informatics Research Vol.29 No.4
Objectives: A substantial portion of the data contained in Electronic Health Records (EHR) is unstructured, often appearingas free text. This format restricts its potential utility in clinical decision-making. Named entity recognition (NER) methodsaddress the challenge of extracting pertinent information from unstructured text. The aim of this study was to outline thecurrent NER methods and trace their evolution from 2011 to 2022. Methods: We conducted a methodological literature reviewof NER methods, with a focus on distinguishing the classification models, the types of tagging systems, and the languagesemployed in various corpora. Results: Several methods have been documented for automatically extracting relevant informationfrom EHRs using natural language processing techniques such as NER and relation extraction (RE). These methodscan automatically extract concepts, events, attributes, and other data, as well as the relationships between them. Most NERstudies conducted thus far have utilized corpora in English or Chinese. Additionally, the bidirectional encoder representationfrom transformers using the BIO tagging system architecture is the most frequently reported classification scheme. Wediscovered a limited number of papers on the implementation of NER or RE tasks in EHRs within a specific clinical domain. Conclusions: EHRs play a pivotal role in gathering clinical information and could serve as the primary source for automatedclinical decision support systems. However, the creation of new corpora from EHRs in specific clinical domains is essential tofacilitate the swift development of NER and RE models applied to EHRs for use in clinical practice.
LMI-Based Robust Controllers for DC-DC Cascade Boost Converters
Torres-Pinzon, Carlos Andres,Giral, Roberto,Leyva, Ramon The Korean Institute of Power Electronics 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.4
This paper presents two different robust controllers for boost converters with two stages in a cascade. The first robust controller is monovariable; that is, the duty-cycle is the same for the two switches. The monovariable controller ensures that some prescribed constraints on pole placement and control effort are met, and optimizes the load disturbance rejection, while takes into account the uncertainty in certain parameters. The first controller is then compared with a multivariable robust controller; that is, with independent duty cycles in each switch. The multivariable controller takes into account the same uncertainty, constraints and optimization function. The comparison shows that the multivariable controller performs better at the expense of a slightly more complex implementation; that is, the multivariable controller provides a better rejection of the load disturbance. The paper also describes simulations and experimental results that are in perfect agreement with theoretical derivations.
Andres Torres,Reinhilde Jacobs,Paul Lambrechts,Claudia Brizuela,Carolina Cabrera,Guillermo Concha,María Eugenia Pedemonte 대한영상치의학회 2015 Imaging Science in Dentistry Vol.45 No.2
Purpose: This study used cone-beam computed tomography (CBCT) to characterize mandibular molar root and canal morphology and its variability in Belgian and Chilean population samples. Materials and Methods: We analyzed the CBCT images of 515 mandibular molars (257 from Belgium and 258 from Chile). Molars meeting the inclusion criteria were analyzed to determine (1) the number of roots; (2) the root canal configuration; (3) the presence of a curved canal in the cross-sectional image of the distal root in the mandibular first molar and (4) the presence of a C-shaped canal in the second mandibular molar. A descriptive analysis was performed. The association between national origin and the presence of a curved or C-shaped canal was evaluated using the chi-squared test. Results: The most common configurations in the mesial root of both molars were type V and type III. In the distal root, type I canal configuration was the most common. Curvature in the cross-sectional image was found in 25% of the distal canals of the mandibular first molars in the Belgian population, compared to 11% in the Chilean population. The prevalence of C-shaped canals was 10% or less in both populations. Conclusion: In cases of unclear or complex root and canal morphology in the mandibular molars, CBCT imaging might assist endodontic specialists in making an accurate diagnosis and in treatment planning.
Torres, Andres,Jacobs, Reinhilde,Lambrechts, Paul,Brizuela, Claudia,Cabrera, Carolina,Concha, Guillermo,Pedemonte, Maria Eugenia Korean Academy of Oral and Maxillofacial Radiology 2015 Imaging Science in Dentistry Vol.45 No.2
Purpose: This study used cone-beam computed tomography (CBCT) to characterize mandibular molar root and canal morphology and its variability in Belgian and Chilean population samples. Materials and Methods: We analyzed the CBCT images of 515 mandibular molars (257 from Belgium and 258 from Chile). Molars meeting the inclusion criteria were analyzed to determine (1) the number of roots; (2) the root canal configuration; (3) the presence of a curved canal in the cross-sectional image of the distal root in the mandibular first molar and (4) the presence of a C-shaped canal in the second mandibular molar. A descriptive analysis was performed. The association between national origin and the presence of a curved or C-shaped canal was evaluated using the chi-squared test. Results: The most common configurations in the mesial root of both molars were type V and type III. In the distal root, type I canal configuration was the most common. Curvature in the cross-sectional image was found in 25% of the distal canals of the mandibular first molars in the Belgian population, compared to 11% in the Chilean population. The prevalence of C-shaped canals was 10% or less in both populations. Conclusion: In cases of unclear or complex root and canal morphology in the mandibular molars, CBCT imaging might assist endodontic specialists in making an accurate diagnosis and in treatment planning.
LMI-Based Robust Controllers for DC-DC Cascade Boost Converters
Carlos Andres Torres-Pinzon,Roberto Giral,Ramon Leyva 전력전자학회 2012 JOURNAL OF POWER ELECTRONICS Vol.12 No.4
This paper presents two different robust controllers for boost converters with two stages in a cascade. The first robust controller is monovariable; that is, the duty-cycle is the same for the two switches. The monovariable controller ensures that some prescribed constraints on pole placement and control effort are met, and optimizes the load disturbance rejection, while takes into account the uncertainty in certain parameters. The first controller is then compared with a multivariable robust controller; that is, with independent duty cycles in each switch. The multivariable controller takes into account the same uncertainty, constraints and optimization function. The comparison shows that the multivariable controller performs better at the expense of a slightly more complex implementation; that is, the multivariable controller provides a better rejection of the load disturbance. The paper also describes simulations and experimental results that are in perfect agreement with theoretical derivations.
From Arithmetic to Algebra: Smoothing the Transition
( Rivera Torres ),( Adrian Andres ) 한국수학교육학회 2014 수학교육 학술지 Vol.2014 No.1
Education in Arithmetic and Geometry is strong because those topics are considered “second nature”, so they are easily associated to real-life problems and the intuition behind their properties is easier to teach. Education in Algebra suffers because it lacks that, so the idea of this presentation is to turn it into “second nature” as well. By combining arithmetic and geometry with topics such as proportionality and the basics of modeling, it will not only improve problem-solving skills among students, but will lead to a better education in Algebra and the many topics that depend on it.
Release of mineral-bound water prior to subduction tied to shallow seismogenic slip off Sumatra
Hupers, Andre,Torres, Marta E.,Owari, Satoko,McNeill, Lisa C.,Dugan, Brandon,Henstock, Timothy J.,Milliken, Kitty L.,Petronotis, Katerina E.,Backman, Jan,Bourlange, Sylvain,Chemale Jr., Farid,Chen, We American Association for the Advancement of Scienc 2017 Science Vol.356 No.6340
<P>Plate-boundary fault rupture during the 2004 Sumatra-Andaman subduction earthquake extended closer to the trench than expected, increasing earthquake and tsunami size. International Ocean Discovery Program Expedition 362 sampled incoming sediments offshore northern Sumatra, revealing recent release of fresh water within the deep sediments. Thermal modeling links this freshening to amorphous silica dehydration driven by rapid burial-induced temperature increases in the past 9 million years. Complete dehydration of silicates is expected before plate subduction, contrasting with prevailing models for subduction seismogenesis calling for fluid production during subduction. Shallow slip offshore Sumatra appears driven by diagenetic strengthening of deeply buried fault-forming sediments, contrasting with weakening proposed for the shallow Tohoku-Oki 2011 rupture, but our results are applicable to other thickly sedimented subduction zones including those with limited earthquake records.</P>