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- 저자 : Amal F Alshammary (검색결과 2 건)
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Amal F Alshammary,Imran Ali Khan 대한비만학회 2021 The Korean journal of obesity Vol.30 No.1
Background: Consanguinity, defined as a blood relation between couples, is associated with genetic diseases in their offspring. In Saudi Arabia, obesity is considered a major health problem associated with increased risks of cardiovascular disease, insulin resistance, and type 2 diabetes mellitus. Angiotensin-converting enzyme (ACE) with insertion (I) and deletion (D) polymorphisms of an Alu-287 bp sequence has been implicated in multiple metabolic disorders, including obesity. To date, no studies have been conducted in the Saudi population regarding the ACE gene in consanguineous offspring with obesity. Therefore, the present study aimed to investigate genetic associations in offspring of first cousins, and specifically the relationship between obesity and ACE (Alu-287 bp) was evaluated in the Saudi population. Methods: In total, 91 cases of obesity in the offspring of first-cousin couples and 100 control subjects without obesity but with a family history of consanguinity were included. Using genomic DNA, ACE ID polymorphisms between the cases and controls were evaluated by polymerase chain reaction. Results: There were strong differences in the height, weight, and body mass index between the cases and controls (P<0.001). A genotype analysis confirmed the strong association with allele frequencies (P<0.001; odds ratio, 4.902; 95% confidence interval, 2.867–8.379) when compared between the cases and controls. One-way analysis of variance showed a positive correlation with height and logistic regression (covariance) that could not be strongly correlated (P>0.05). Conclusion: In conclusion, the ACE gene polymorphism was found, through allele frequencies, to be associated with obesity in the offspring of consanguineous first cousins in the Saudi population.
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Amal T. Mogharbel,Saham F. Ibarhiam,Alaa M. Alqahtani,Roba M.S. Attar,Khaled F. Alshammari,Majid A. Bamaga,Salhah D. Al-Qahtani,Nashwa M. El-Metwaly 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.127 No.-
The preparation of multifunctional polyester fabric has been recently attractive research. Herein, a compositefilm of silver nanoparticles (AgNPs) and polypyrrole (Ppyr) were prepared and incorporated in situinto plasma-pretreated polyesters using the pad-dry-cure procedure of silver nitrate and pyrrole intopolyester to provide a multifunctional textile. Recycled polyester waste was shredded and melt-spunto provide nonwoven fabric. Polypyrrole was generated in situ via REDOX polymerization process of pyrrole. This polymerization process was accompanied with reduction of Ag+ to Ag0 NPs, leading to permanentinsoluble property within the structure of the polyester fibers. Thus, high colorfastness wasmonitored without varying the comfort features of the finished polyesters. The produced polypyrroleacted an electrically conductive agent, whereas silver nitrate functioned as an antmicrobial agent. By curingwith hexadecyltrimethoxysilane (HDTMS), the superhydrophobic properties were imparted to polyesterfabrics. The morphological studies were explored by energy-dispersive X-ray spectroscopy (EDX),transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and scanningelectron microscope (SEM). The bend length and air-permeability of the finished polyesters were investigatedto assess their comfort characteristics. The antibacterial behavior to S. aureus and E. coli wereexamined. Additionally, the finished fabrics showed ultraviolet shielding and electrical conductivity.
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