MULTIPLIER THEOREMS IN WEIGHTED SMIRNOV SPACES

Guven, Ali,Israfilov, Daniyal M. Korean Mathematical Society 2008 대한수학회지 Vol.45 No.6

The analogues of Marcinkiewicz multiplier theorem and Littlewood-Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve.

Multiplier theorems in weighted Smirnov spaces

Ali Guven,Daniyal M. Israfilov 대한수학회 2008 대한수학회지 Vol.45 No.6

The analogues of Marcinkiewicz multiplier theorem and Littlewood- Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve. The analogues of Marcinkiewicz multiplier theorem and Littlewood- Paley theorem are proved for p-Faber series in weighted Smirnov spaces defined on bounded and unbounded components of a rectifiable Jordan curve.

Prognostic Factors in First-Line Chemotherapy Treated Metastatic Gastric Cancer Patients: A Retrospective Study

Inal, Ali,Kaplan, M. Ali,Kucukoner, Mehmet,Urakci, Zuhat,Guven, Mehmet,Nas, Necip,Yunce, Muharrem,Isikdogan, Abdurrahman Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8

Background: The majority of patients with gastric cancer in developing countries present with advanced disease. Systemic chemotherapy therefore has limited impact on overall survival. Patients eligible for chemotherapy should be selected carefully. The aim of this study was to analyze prognostic factors for survival in advanced gastric cancer patients undergoing first-line palliative chemotherapy. Methods: We retrospectively reviewed 107 locally advanced or metastatic gastric cancer patients who were treated with docetaxel and cisplatin plus fluorouracil (DCF) as first-line treatment between June 2007 and August 2011. Twenty-eight potential prognostic variables were chosen for univariate and multivariate analyses. Results: Among the 28 variables of univariate analysis, nine variables were identified to have prognostic significance: performance status, histology, location of primary tumor, lung metastasis, peritoneum metastasis, ascites, hemoglobin, albumin, weight loss and bone metastasis. Multivariate analysis by Cox proportional hazard model, including nine prognostic significance factors evident in univariate analysis, revealed weight loss, histology, peritoneum metastasis, ascites and serum hemoglobin level to be independent variables. Conclusion: Performance status, weight loss, histology, peritoneum metastasis, ascites and serum hemoglobin level were identified as important prognostic factors in advanced gastric cancer patients. These findings may facilitate pretreatment prediction of survival and can be used for selecting patients for treatment.

Is Diabetes Mellitus a Prognostic Factor for Survival in Patients with Small Cell Lung Cancer?

Inal, Ali,Kaplan, M. Ali,Kucukoner, Mehmet,Urakci, Zuhat,Karakus, Abdullah,Nas, Necip,Guven, Mehmet,Isikdogan, Abdurrahman Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Background: Previous studies have pointed to many different prognostic factors for small cell lung cancer (SCLC) but diabetes mellitus (DM) has not been clearly or consistently identified as of prognostic value. The aim of this study was to investigate the prognostic significance of the characteristics of patients and clinical laboratory tests in SCLC. Specifically, we investigated that the impact of DM for survival in the patients receiving first-line etoposide plus cisplatin (EP) chemotherapy. Methods: We retrospectively reviewed 161 patients with SCLC with a focus on DM and other potential prognostic variables were chosen for univariate and multivariate analyses with respect to survival. Result: Among the sixteen variables of univariate analysis, five were identified to have prognostic significance: performance status (PS) (p<0.001), stage (p=0.001), DM (p=0.005), serum albumin (p<0.001) and hemoglobin levels (p=0.03). Multivariate analysis showed PS, stage and serum albumin level to be independent prognostic factors for survival (p=0.02, p=0.02 and p=0.009 respectively), but DM was not an independnet factor. Conclusion: In conclusion, PS, stage and serum albumin level were identified as important prognostic factors, while DM at the time of diagnosis of SCLC did not have prognostic importance for survival.

The Neuroprotective Effect of Kefir on Spinal Cord Ischemia/Reperfusion Injury in Rats

Guven, Mustafa,Akman, Tarik,Yener, Ali Umit,Sehitoglu, Muserref Hilal,Yuksel, Yasemin,Cosar, Murat The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.57 No.5

Objective : The main causes of spinal cord ischemia are a variety of vascular pathologies causing acute arterial occlusions. We investigated neuro-protective effects of kefir on spinal cord ischemia injury in rats. Methods : Rats were divided into three groups : 1) sham operated control rats; 2) spinal cord ischemia group fed on a standard diet without kefir pretreatment; and 3) spinal cord ischemia group fed on a standard diet plus kefir. Spinal cord ischemia was performed by the infrarenal aorta cross-clamping model. The spinal cord was removed after the procedure. The biochemical and histopathological changes were observed within the samples. Functional assessment was performed for neurological deficit scores. Results : The kefir group was compared with the ischemia group, a significant decrease in malondialdehyde levels was observed (p<0.05). Catalase and superoxide dismutase levels of the kefir group were significantly higher than ischemia group (p<0.05). In histopathological samples, the kefir group is compared with ischemia group, there was a significant decrease in numbers of dead and degenerated neurons (p<0.05). In immunohistochemical staining, hipoxia-inducible factor-$1{\alpha}$ and caspase 3 immunopositive neurons were significantly decreased in kefir group compared with ischemia group (p<0.05). The neurological deficit scores of kefir group were significantly higher than ischemia group at 24 h (p<0.05). Conclusion : Our study revealed that kefir pretreatment in spinal cord ischemia/reperfusion reduced oxidative stress and neuronal degeneration as a neuroprotective agent. Ultrastructural studies are required in order for kefir to be developed as a promising therapeutic agent to be utilized for human spinal cord ischemia in the future.

Evaluation and comparison of the marginal adaptation of two different substructure materials

Sedat Guven,Veysel Eratilla,Ebru Sumer,Ali Ihsan Zengingul,Sabiha Zelal Ulku,Tahir Karaman 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

PURPOSE In this study, we aimed to evaluate the amount of marginal gap with two different substructure materials using identical margin preparations. MATERIALS AND METHODS Twenty stainless steel models with a chamfer were prepared with a CNC device. Marginal gap measurements of the galvano copings on these stainless steel models and Co-Cr copings obtained by a laser-sintering method were made with a stereomicroscope device before and after the cementation process and surface properties were evaluated by scanning electron microscopy (SEM). A dependent t-test was used to compare the mean of the two groups for normally distributed data, and two-way variance analysis was used for more than two data sets. Pearson's correlation analysis was also performed to assess relationships between variables. RESULTS According to the results obtained, the marginal gap in the galvano copings before cementation was measured as, on average, 24.47 ± 5.82 µm before and 35.11 ± 6.52 µm after cementation; in the laser-sintered Co-Cr structure, it was, on average, 60.45 ± 8.87 µm before and 69.33 ± 9.03 µm after cementation. A highly significant difference (P<.001) was found in marginal gap measurements of galvano copings and a significant difference (P<.05) was found in marginal gap measurements of the laser-sintered Co-Cr copings. According to the SEM examination, surface properties of laser sintered Co-Cr copings showed rougher structure than galvano copings. The galvano copings showed a very smooth surface. CONCLUSION Marginal gaps values of both groups before and after cementation were within the clinically acceptable level. The smallest marginal gaps occurred with the use of galvano copings.

Poster Session : PS 0312 ; Hematology : Hemolysis Following Mitral Ring Annuloplasty and Iron Defi ciency Anemia Case Caused by Duodenal Diverticulum

( Zeynep Tugba Guven ),( Selma Karaahmetoglu ),( Ali Atilla Aydin ),( Rukiye Kara ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Introduction: Hemolytic anemia, following mitral ring annuloplasty, is a rare entity. In this case hemolysis following mitral ring annuloplasty and iron defi ciency anemia caused by duodenal diverticulum will be presented. Case report: 55 years old women admitted to our Internal Medicine Department with the complaints of weakness, fatigue and dispnea. She had history of hypertension and coronary artery disease. Her complaints had been beginning two months after the mitral annuloplasty operation. Her physical examination revealed; subicterus, paleness of conjunctuvia and 3/6 systolic murmur on mitral region. In biochemical evolution; Hemoglobin 7. 2 mg/dl, Htc 25. 4%, total bilirubin 2. 7 mg/dl, direct bilirubin 0. 8 mg/ dl, LDH 1881 U/L. There wasn`t occult blood in the stool. Both LDH1 and LDH2 were increased. Hypochromia, microcytosis and anisocytosis was detected in the peripheral blood smear and reticulocyte value was 3. 1%. Serum iron level 28 mg/dl, iron binding capacity 357 mg/dl, ferritin 21. 4 mg/dl and haptoglobin level was 7. 2 mg/dl. Direct coombs test was detected +2. findings were supporting hemolytic anemia. Ejection fraction was calculated in normal range at transthoracic echocardiography. There was an annuloplasty ring at mitral level, third degree mitral regurgitation and left atrial dilatation. TEE was supporting the same fi ndings. Gastroduodenoscopy revealed; a large and deep diverticulum in postbulbar area and in the second part of duodenum. Since the patient did not accept coronary artery angiography and the operation, she was discharged. Conclusion: We decided that intravascular hemolysis was due to mitral valve annuloplasty. After this operation, hemolytic anemia is a rare condition. Because if a patient admits after valvular operation with anemia; we should keep in mind that it can be hemolytic anemia. The patient should be examined in terms of other types of anemia like iron defi ciency anemia.

Nearly k-th Partial Ternary Quadratic *-Derivations

ARSLAN, BERNA,INCEBOZ, HULYA,GUVEN, ALI Department of Mathematics 2015 Kyungpook mathematical journal Vol.55 No.4

The Hyers-Ulam-Rassias stability of the k-th partial ternary quadratic derivations is investigated in non-Archimedean Banach ternary algebras and non-Archimedean $C^*$-ternary algebras by using the fixed point theorem.

Evaluation and comparison of the marginal adaptation of two different substructure materials

Karaman, Tahir,Ulku, Sabiha Zelal,Zengingul, Ali Ihsan,Guven, Sedat,Eratilla, Veysel,Sumer, Ebru The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.3

PURPOSE. In this study, we aimed to evaluate the amount of marginal gap with two different substructure materials using identical margin preparations. MATERIALS AND METHODS. Twenty stainless steel models with a chamfer were prepared with a CNC device. Marginal gap measurements of the galvano copings on these stainless steel models and Co-Cr copings obtained by a laser-sintering method were made with a stereomicroscope device before and after the cementation process and surface properties were evaluated by scanning electron microscopy (SEM). A dependent t-test was used to compare the mean of the two groups for normally distributed data, and two-way variance analysis was used for more than two data sets. Pearson's correlation analysis was also performed to assess relationships between variables. RESULTS. According to the results obtained, the marginal gap in the galvano copings before cementation was measured as, on average, $24.47{\pm}5.82{\mu}m$ before and $35.11{\pm}6.52{\mu}m$ after cementation; in the laser-sintered Co-Cr structure, it was, on average, $60.45{\pm}8.87{\mu}m$ before and $69.33{\pm}9.03{\mu}m$ after cementation. A highly significant difference (P<.001) was found in marginal gap measurements of galvano copings and a significant difference (P<.05) was found in marginal gap measurements of the laser-sintered Co-Cr copings. According to the SEM examination, surface properties of laser sintered Co-Cr copings showed rougher structure than galvano copings. The galvano copings showed a very smooth surface. CONCLUSION. Marginal gaps values of both groups before and after cementation were within the clinically acceptable level. The smallest marginal gaps occurred with the use of galvano copings.

Evaluation of Biochemical Recurrence-free Survival after Radical Prostatectomy by Cancer of the Prostate Risk Assessment Post-Surgical (CAPRA-S) Score

Aktas, Binhan Kagan,Ozden, Cuneyt,Bulut, Suleyman,Tagci, Suleyman,Erbay, Guven,Gokkaya, Cevdet Serkan,Baykam, Mehmet Murat,Memis, Ali Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.6

Background: The cancer of the prostate risk assessment (CAPRA) score has been defined to predict prostate cancer recurrence based on the pre-clinical data, then pathological data have also been incorporated. Thus, CAPRA post-surgical (CAPRA-S) score has been developed based on six criteria (prostate specific antigen (PSA) at diagnosis, pathological Gleason score, and information on surgical margin, seminal vesicle invasion, extracapsular extension and lymph node involvement) for the prediction of post-surgical recurrences. In the present study, biochemical recurrence (BCR)-free probabilities after open retropubic radical prostatectomy (RP) were evaluated by the CAPRA-S scoring system and its three-risk level model. Materials and Methods: CAPRA-S scores (0-12) of our 240 radical prostatectomies performed between January 2000-May 2011 were calculated. Patients were distributed into CAPRA-S score groups and also into three-risk groups as low, intermediate and high. BCR-free probabilities were assessed and compared using Kaplan-Meier analysis and Cox proportional hazards regression. Ability of CAPRA-S in BCR detection was evaluated by concordance index (c-index). Results: BCR was present in 41 of total 240 patients (17.1%) and the mean follow-up time was $51.7{\pm}33.0$ months. Mean BCR-free survival time was 98.3 months (95% CI: 92.3-104.2). Of the patients in low, intermediate and high risk groups, 5.4%, 22.0% and 58.8% had BCR, respectively and the difference among the three groups was significant (P = 0.0001). C-indices of CAPRA-S score and three-risk groups for detecting BCR-free probabilities in 5-yr were 0.87 and 0.81, respectively. Conclusions: Both CAPRA-S score and its three-risk level model well predicted BCR after RP with high c-index levels in our center. Therefore, it is a clinically reliable post-operative risk stratifier and disease recurrence predictor for prostate cancer.