The effects of repetitive transcranial magnetic stimulation on proliferation and differentiation of neural stem cells

Ali Ghanbari,Sharareh Sharififar,Mehrnaz Abedian,Amir Ghanbari,Keramatollah Abbasnia 대한해부학회 2015 Anatomy & Cell Biology Vol.48 No.2

Repetitive transcranial magnetic stimulation (rTMS) is a new method for treating many neurological conditions; however, the exact therapeutic mechanisms behind rTMS-induced plasticity are still unknown. Neural stem and progenitor cells (NS/PCs) are active players in brain regeneration and plasticity but their behavior in the context of rTMS therapy needs further elucidation. We aimed to evaluate the effects of rTMS on proliferation and differentiation of NS/PCs in the subventricular zone (SVZ) of adult mouse brain. Adult male mice (n=30) were divided into rTMS (1-Hz and 30-Hz) and sham groups and treated for 7 or 14 consecutive days. Harvested NS/PCs from the SVZ were cultured in the neurosphere assay for 8 days and the number and size of the resulting neurospheres as well as their in vitro differentiation capacity were evaluated. After one week of rTMS treatment at 1-Hz and 30-Hz compared with sham stimulation, the mean neurosphere forming frequency per brain was not different while this measure significantly increased after two weeks (P

Electromagnetic Steering of a Magnetic Cylindrical Microrobot Using Optical Feedback Closed-Loop Control

Ghanbari, Ali,Chang, Pyung H.,Nelson, Bradley J.,Choi, Hongsoo Taylor Francis 2014 International journal of optomechatronics Vol.8 No.2

An analytical technique for estimation of seismic displacements in reinforced slopes based on horizontal slices method (HSM)

Ghanbari, Ali,Khalilpasha, Abbas,Sabermahani, Mohsen,Heydari, Babak Techno-Press 2013 Geomechanics & engineering Vol.5 No.2

Calculation of seismic displacements in reinforced slopes plays a crucial role in appropriate design of these structures however current analytical methods result indifferent values for permanent displacements of the slope. In this paper, based on limit equilibrium and using the horizontal slices method, a new formulation has been proposed for estimating the seismic displacements of a reinforced slope under earthquake records. In this method, failure wedge is divided into a number of horizontal slices. Assuming linear variations for tensile forces of reinforcements along the height of the slope, the coefficient of yield acceleration has been estimated. The simplicity of calculations and taking into account the frequency content of input triggers are among the advantages of the present formulation. Comparison of the results shows that the yield acceleration calculated by the suggested method is very close to the values resulted from other techniques. On the other hand, while there is a significant difference between permanent displacements, the values obtained from the suggested method place somehow between those calculated by the other techniques.

Spatial Analysis of Common Gastrointestinal Tract Cancers in Counties of Iran

Soleimani, Ali,Hassanzadeh, Jafar,Motlagh, Ali Ghanbari,Tabatabaee, Hamidreza,Partovipour, Elham,Keshavarzi, Sareh,Hossein, Mohammad Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Background: Gastrointestinal tract cancers are among the most common cancers in Iran and comprise approximately 38% of all the reported cases of cancer. This study aimed to describe the epidemiology and to investigate spatial clustering of common cancers of the gastrointestinal tract across the counties of Iran using full Bayesian smoothing and Moran I Index statistics. Materials and Methods: The data of the national registry cancer were used in this study. Besides, indirect standardized rates were calculated for 371 counties of Iranand smoothed using Winbug 1.4 software with a full Bayesian method. Global Moran I and local Moran I were also used to investigate clustering. Results: According to the results, 75,644 new cases of cancer were nationally registered in Iran among which 18,019 cases (23.8%) were esophagus, gastric, colorectal, and liver cancers. The results of Global Moran's I test were 0.60 (P=0.001), 0.47 (P=0.001), 0.29 (P=0.001), and 0.40 (P=0.001) for esophagus, gastric, colorectal, and liver cancers, respectively. This shows clustering of the four studied cancers in Iran at the national level. Conclusions: High level clustering of the cases was seen in northern, northwestern, western, and northeastern areas for esophagus, gastric, and colorectal cancers. Considering liver cancer, high clustering was observed in some counties in central, northeastern, and southern areas.

Exploring neighborhood inequality in female breast cancer incidence in Tehran using Bayesian spatial models and a spatial scan statistic

Erfan Ayubi,Mohammad Ali Mansournia1,Ali Ghanbari Motlagh,Alireza Mosavi-Jarrahi,Ali Hosseini,Kamran Yazdani 한국역학회 2017 Epidemiology and Health Vol.39 No.-

OBJECTIVES: The aim of this study was to explore the spatial pattern of female breast cancer (BC) incidence at the neighborhood level in Tehran, Iran. METHODS: The present study included all registered incident cases of female BC from March 2008 to March 2011. The raw standardized incidence ratio (SIR) of BC for each neighborhood was estimated by comparing observed cases relative to expected cases. The estimated raw SIRs were smoothed by a Besag, York, and Mollie spatial model and the spatial empirical Bayesian method. The purely spatial scan statistic was used to identify spatial clusters. RESULTS: There were 4,175 incident BC cases in the study area from 2008 to 2011, of which 3,080 were successfully geocoded to the neighborhood level. Higher than expected rates of BC were found in neighborhoods located in northern and central Tehran, whereas lower rates appeared in southern areas. The most likely cluster of higher than expected BC incidence involved neighborhoods in districts 3 and 6, with an observed-to-expected ratio of 3.92 (p〈0.001), whereas the most likely cluster of lower than expected rates involved neighborhoods in districts 17, 18, and 19, with an observed-to-expected ratio of 0.05 (p〈0.001). CONCLUSIONS: Neighborhood-level inequality in the incidence of BC exists in Tehran. These findings can serve as a basis for resource allocation and preventive strategies in at-risk areas.

Evaluating phylogenetic relationships in the Lilium family using the ITS marker

Ghanbari, Sina,Fakheri, Barat Ali,Naghavi, Mohammad Reza,Mahdinezhad, Nafiseh The Korean Society of Plant Biotechnology 2018 식물생명공학회지 Vol.45 No.3

Lilium is a perennial bulbous plant belonging to the liriotypes genus. Our aim was to study the phylogenetic relationships of the Lilium family. Two varieties of Lilium ledebourii, 44 varieties of the gene bank, and one variety from the Tulipa family served as the out group. In order to study the diversity between lilium masses, ITS regions were used to design the marker. The results showed that the guanine base is the most abundant nucleotide. Relatively high conservation was observed in the ITS regions of the populations (0.653). Phylogenetic analysis showed that sargentiae and hybrid varieties are older than other varieties of the Lilium family. Also, the location of L. ledebourii varieties (Damash and Namin) was identified in a phylogenetic tree by using the ITS marker. Overall, our research showed that ITS molecular markers are very suitable for phylogenetic studies in the Lilium family.

New protocol for the indirect regeneration of the Lilium ledebourii Bioss by using bulb explants

Ghanbari, Sina,Fakheri, Barat Ali,Naghavi, Mohammad Reza,Mahdinezhad, Nafiseh The Korean Society of Plant Biotechnology 2018 식물생명공학회지 Vol.45 No.2

Lilium ledebourii Bioss is a wild species of Lilium, which grows naturally in some provinces of Iran. Previous studies on Lilium tissue culture have been linked to direct regeneration and a few studies have been conducted on indirect regeneration, which has been studied under bright conditions. In this study, for the first time in the world, all the stages of indirect regeneration (callus induction, shoot and root induction) have been studied under dark conditions. Callus formation and the regeneration levels of L. Ledebourii Bioss were examined for three replicates in an MS (Murashige and Skoog) medium with different hormonal compositions and by using a factorial experiment in the framework of a completely random plan. For callus initiation, 2,4-D and kinetin hormones were used in five and four levels, respectively, as auxin and cytokinin. Results showed that the highest percentage of the callus was found in $3{\mu}M$ of 2,4-D and $0.5{\mu}M$ of kinetin. In terms of callus wet weight, the highest amount was found in $3{\mu}M$ of 2,4-D and $0.5{\mu}M$ of kinetin. In addition, in terms of diameter, the highest amount was found in $3{\mu}M$ of 2,4-D, and $0.5{\mu}M$ of kinetin. In summary, the 2,4-D hormone had a major impact on the percentage of regeneration increase so that the best response was related to the composition of $3{\mu}M$ of 2,4-D, and $0.1{\mu}M$ of kinetin. This study contended that auxin and cytokinin can induce long shoots and roots through cell elongation in dark condition.

Effect of a smartphone-based online electronic logbook to evaluate the clinical skills of nurse anesthesia students in Iran: a randomized controlled study

Ali Khalafi,Nahid Jamshidi,Nasrin Khajeali,Saeed Ghanbari 한국보건의료인국가시험원 2023 보건의료교육평가 Vol.20 No.-

Purpose This study was conducted to evaluate a smartphone-based online electronic logbook used to assess the clinical skills of nurse anesthesia students in Iran. Methods This randomized controlled study was conducted after tool development at Ahvaz Jundishapur University of Medical Sciences in Ahvaz, Iran from January 2022 to December 2022. The online electronic logbook involved in this study was an Android-compatible application used to evaluate the clinical skills of nurse anesthesia students. In the implementation phase, the online electronic logbook was piloted for 3 months in anesthesia training in comparison with a paper logbook. For this purpose, 49 second- and third-year anesthesia nursing students selected using the census method were assigned to intervention (online electronic logbook) and control (paper logbook) groups. The online electronic logbook and paper logbook were compared in terms of student satisfaction and learning outcomes. Results A total of 39 students participated in the study. The mean satisfaction score of the intervention group was significantly higher than that of the control group (P=0.027). The mean score of learning outcomes was also significantly higher for the intervention than the control group (P=0.028). Conclusion Smartphone technology can provide a platform for improving the evaluation of the clinical skills of nursing anesthesia students, leading to increased satisfaction and improved learning outcomes.

Evaluating phylogenetic relationships in the Lilium family using the ITS marker

Sina Ghanbari,Barat Ali Fakheri,Mohammad Reza Naghavi,Nafiseh Mahdinezhad 한국식물생명공학회 2018 JOURNAL OF PLANT BIOTECHNOLOGY Vol.45 No.3

Lilium is a perennial bulbous plant belonging to the liriotypes genus. Our aim was to study the phylogenetic relationships of the Lilium family. Two varieties of Lilium ledebourii, 44 varieties of the gene bank, and one variety from the Tulipa family served as the out group. In order to study the diversity between lilium masses, ITS regions were used to design the marker. The results showed that the guanine base is the most abundant nucleotide. Relatively high conservation was observed in the ITS regions of the populations (0.653). Phylogenetic analysis showed that sargentiae and hybrid varieties are older than other varieties of the Lilium family. Also, the location of L. ledebourii varieties (Damash and Namin) was identified in a phylogenetic tree by using the ITS marker. Overall, our research showed that ITS molecular markers are very suitable for phylogenetic studies in the Lilium family.

Evaluation of peroxymonosulfate/O3/UV process on a real polluted water with landfill leachate: Feasibility and comparative study

Farshid Ghanbari,Masoumeh Khatebasreh,Mostafa Mahdavianpour,Ali Mashayekh-Salehi,Ehsan Aghayani,Kun-Yi Andrew Lin,Behnam Kazemi Noredinvand 한국화학공학회 2021 Korean Journal of Chemical Engineering Vol.38 No.7

Landfill leachate is classified as special wastewater because it contains a large amount of hazardous materials that can lead to the pollution of surface water, generating polluted water with landfill leachate (PWLL) with high organic load. This study investigated the treatment of PWLL by peroxymonosulfate (PMS)/O3/UV process. The effects of several operating parameters such as pH, reaction time, O3 and PMS dosage were investigated in detail. The results showed that PMS/O3/UV removed total organic carbon (TOC) (74%), color (98%), ammonia (93%), chemical oxygen demand (COD) (81%), and biochemical oxygen demand (BOD) (69%) in 75 min at optimal conditions (pH=7, PMS=5mM, O3=1.7 mg/min). According to the results, O3 and UV can well activate PMS and promote the ability of the process to remove TOC from PWLL. Adding ferrous ion to PMS/O3/UV increased the TOC removal efficiency (77%), but cobalt ions had no significant effect on the TOC removal. The elimination of TOC by the PMS/O3/UV process follows pseudo-first-order kinetic model with the reaction rate constant of 0.0203 min1. Compared to peroxone/ UV, PMS/O3/UV showed high yield in TOC, COD, color and ammonia removal. Thus the PMS/O3/UV process can be a new approach for treatment of polluted water in low volume.