Explicit about Impact of E-Marketing on Customer Perceived Quality in Tourism

Establishments in Alexandria 세계문화관광학회 2011 Conference Proceedings Vol.12 No.-

Alexandria 2010 Capital of Arab Tourism it is rich in various features of tourism such as cultural and entertainment events conferences festivals exhibitions and maritime tourism in addition to other touristic outlines that help in attracting different classes of tourists. So most of marketing departments in different tourism establishments in Alexandria try to achieve its objectives using the internet in the provision of services and quality assurance to customers In addition to the ability to search for different ways to help those establishments to achieve satisfaction from its customers. The study aims to recognize customers' perception of tourism establishments in Alexandria and contribute providing a database and information that will help tourism establishments to adopt the concept of e-marketing in dealing with customers. The present study was a descriptive analytical study of 230 questionnaires on different Egyptian customers of tourism establishments in Alexandria 200 only complete and valid for statistical analysis with a respondent rate of 87%. The study concluded that the tourism establishments which provide and improve different information to their customers and develop its e-marketing tools can attract many of them to satisfy their different needs and also there is a relationship between the availability of a database for marketing and e-marketing impact on tourism services. The study recommends: providing databases and marketing information to help customers meet their needs and assist them in making their decisions and there is a need for increasing the awareness of e-marketing concept between employees and customers and encouraging them to deal with internet and websites.

Antinociceptive and Anti-Inflammatory Properties of Cannabidiol Alone and in Combination with Standardized Bioflavonoid Composition

Mesfin Yimam,Alexandria O'Neal,Teresa Horm,Ping Jiao,Mei Hong,Shayna Rossiter,Lidia Brownell,Qi Jia 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.9

Symptom-alleviating therapies for osteoarthritis (OA) management are inadequate. Long-term application of first-line treatments, such as nonsteroidal anti-inflammatory drugs, is limited due to associated side effects. We believe that a combination of traditionally used botanical extracts, which have diverse active components that target multiple inflammatory pathways, may provide a safe and efficacious alternative to address the multifactorial nature of OA. Recently, cannabidiol (CBD), the major nonpsychoactive component of the hemp plant, has gained renewed global attention for its pharmacological actions. It has shown promise in reducing pain and inflammation in preclinical models of arthritis. In this study, widely employed inflammatory and noninflammatory animal pain models, such as the hot plate test, visceral pain model (writhing test), and carrageenan-induced rat paw edema model, were utilized to evaluate the antinociceptive and anti-inflammatory activity of CBD alone and in combination with standardized bioflavonoid compositions. CBD was tested at 5, 10, 20, and 40 mg/kg orally and at 5% topically. Administered alone, CBD produced dose-correlated, statistically significant pain inhibition in all the models. Enhanced performance in pain and inflammation reduction was observed when CBD was orally administered in complex with the bioflavonoid compositions. Data from this study show that for clinically meaningful efficacy against OA, CBD may have to be delivered in higher dosage or formulated with other medicinal plants with similar activities.

Investigating the Characteristics of Sit to Walk for Geriatric Residents of Assisted Living Facilities

( Taylor Braden ),( Madison Burtch ),( Samantha Mott ),( Alexandria Pyle ),( Lee Atkins ),( Heather Braden ) 대한신경치료학회 2021 신경치료 Vol.25 No.1

Purpose Assessing functional mobility is an important aspect of determining fall risk in the growing population of assisted living. Little is known about the sit-to-walk (STW) transition, especially what characteristics correlate with the duration it takes to perform a STW. Methods In this cross-sectional, exploratory study, 45 assisted living residents were evaluated for baseline measures: history of falls, assistive device (AD), lower-extremity strength, and balance (Tinetti POMA). The residents were then timed performing a STW, and, from these durations, were stratified into fast and slow groups. Statistical analysis was performed to determine relationships between the two duration groups and the baseline measures. Results Participants who had experienced a fall were significantly more likely to use an assistive device (p = 0.001). The use of an AD had a moderate negative correlation with composite strength (r = -0.428, p = 0.003). Duration of STW had a weak negative correlation with composite strength (r = -0.299, p = 0.046) and a moderate correlation with use of AD (r = 0.419, p = 0.004). Those with a faster duration of STW had significantly better balance (p = 0.027). Conclusion These correlations support the need for healthcare professionals to address the use of adaptive equipment and physical training when evaluating functional mobility in assisted living residents. Providing appropriate equipment and improving overall strength in these individuals can help reduce their risk of falls. Individuals in assisted living facilities can be assessed similar to other geriatric populations, with special consideration on functional tasks and measures.

Concurrent Isolation of 3 Distinct Cardiac Stem Cell Populations From a Single Human Heart Biopsy

Monsanto, Megan M.,White, Kevin S.,Kim, Taeyong,Wang, Bingyan J.,Fisher, Kristina,Ilves, Kelli,Khalafalla, Farid G.,Casillas, Alexandria,Broughton, Kathleen,Mohsin, Sadia,Dembitsky, Walter P.,Sussman, Grune & Stratton 2017 Circulation research Vol.121 No.2

<P><B><U>Rationale:</U></B></P><P>The relative actions and synergism between distinct myocardial-derived stem cell populations remain obscure. Ongoing debates on optimal cell population(s) for treatment of heart failure prompted implementation of a protocol for isolation of multiple stem cell populations from a single myocardial tissue sample to develop new insights for achieving myocardial regeneration.</P><P><B><U>Objective:</U></B></P><P>Establish a robust cardiac stem cell isolation and culture protocol to consistently generate 3 distinct stem cell populations from a single human heart biopsy.</P><P><B><U>Methods and Results:</U></B></P><P>Isolation of 3 endogenous cardiac stem cell populations was performed from human heart samples routinely discarded during implantation of a left ventricular assist device. Tissue explants were mechanically minced into 1 mm<SUP>3</SUP> pieces to minimize time exposure to collagenase digestion and preserve cell viability. Centrifugation removes large cardiomyocytes and tissue debris producing a single cell suspension that is sorted using magnetic-activated cell sorting technology. Initial sorting is based on tyrosine-protein kinase Kit (c-Kit) expression that enriches for 2 c-Kit<SUP>+</SUP> cell populations yielding a mixture of cardiac progenitor cells and endothelial progenitor cells. Flowthrough c-Kit<SUP>−</SUP> mesenchymal stem cells are positively selected by surface expression of markers CD90 and CD105. After 1 week of culture, the c-Kit<SUP>+</SUP> population is further enriched by selection for a CD133<SUP>+</SUP> endothelial progenitor cell population. Persistence of respective cell surface markers in vitro is confirmed both by flow cytometry and immunocytochemistry.</P><P><B><U>Conclusions:</U></B></P><P>Three distinct cardiac cell populations with individualized phenotypic properties consistent with cardiac progenitor cells, endothelial progenitor cells, and mesenchymal stem cells can be successfully concurrently isolated and expanded from a single tissue sample derived from human heart failure patients.</P>