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- 저자 : Alessio Gori (검색결과 3 건)
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Serum homocysteine concentration in dogs with immunosuppressant-responsive enteropathy
Elena Benvenuti,Alessio Pierini,Eleonora Gori,Enrico Botter,Marco Pietra,Ilaria Lippi,Valentina Meucci,Veronica Marchetti 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.4
Background: Homocysteine (HCY) was evaluated in healthy and chronic enteropathic dogs, however no studies on dogs with immunosuppressant-responsive enteropathy are available. Objectives: The aim was to evaluate serum HCY concentrations and its prognostic role in dogs with immunosuppressant-responsive enteropathy compared to healthy dogs. Methods: Serum HCY concentration was statistically compared between 24 healthy dogs and 29 dogs with immunosuppressant-responsive enteropathy. Correlation analyses between serum total protein, albumin (ALB), C-reactive protein (CRP), folate and cobalamin, and serum HCY concentration were performed in immunosuppressant-responsive enteropathic dogs. Results: The associations between serum HCY concentration and clinical, histological, endoscopic scores and follow-up were evaluated. Mean serum HCY concentration was higher in immunosuppressant-responsive enteropathic dogs compared to control dogs (30.22 ± 8.67 μmol/L vs. 5.26 ± 2.78 μmol/L; p < 0.0001). No association between serum HCY concentration and total protein, ALB, CRP, folate concentration as well as, clinical score, histological and endoscopic scores was found. A negative correlation between serum HCY concentration and cobalamin was noted (p = 0.0025, r = −0.54). No significant difference in HCY was found between responsive and non-responsive dogs or between survivors and non-survivors. Conclusions: Although, serum HCY concentration was higher in immunosuppressant-responsive enteropathy, its prognostic value remains unclear. However, further prospective, large-scale studies are warranted to better investigate the possible prognostic role of HCY in immunosuppressant-responsive enteropathic dogs.
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Giuseppe Craparo,Palmira Faraci,Alessio Gori 대한신경정신의학회 2015 PSYCHIATRY INVESTIGATION Vol.12 No.4
ObjectiveaaAlexithymia is a personality construct that inhibits and interferes with normal affect regulating abilities. The purpose of our study was to assess psychometric properties of TAS-20 in younger adolescents. MethodsaaData were collected from 508 younger adolescents (48.8% male and 51.2% female) with a mean age of 12.56 years (DS=0.50, range: 12–13 years). We administered the following scales: 20-Item-Toronto Alexithymia Scale. ResultsaaThe confirmatory factor analysis performed on the second random subsample showed reasonable goodness-of-fit for the oblique bi-factorial model: [chi]2 (32, n=254)=54.22; p=0.008; χ2/df=1.69; NNFI=0.92; CFI=0.95; SRMR=0.05; RMSEA=0.05; 90% confidence interval=0.027–0.078. ConclusionaaBased on the outcomes of our research we support the idea of evaluating adolescents for alexithymia.
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The Relationships between Early Trauma, Dissociation, and Alexithymia in Alcohol Addiction
Giuseppe Craparo,Vittoria Ardino,Alessio Gori,Vincenzo Caretti 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.3
Objective-Addiction is often considered a dissociative behavior that is related to alexithymia and developmental trauma. The study aims were to explore the relationships between early trauma, alexithymia, and dissociation. Methods-A total of 117 (males=60; females=57) alcohol-addicted individuals and 117 healthy individuals (males=60; females=57) were administered a series of self-report questionnaires that assess traumatic experiences, alexithymia, and pathological dissociation. Results-Correlation analyses indicated significant correlations between alexithymia, dissociation, and trauma and a significant difference between the target and control groups, with higher alexithymia and dissociation scores in the target group. Conclusion-These findings suggest that trauma, alexithymia, and dissociation are predictors of alcohol addiction.
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