http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
On the Numerical Inversion of the Laplace Transform by the Use of an Optimized Legendre Polynomial
Abdulaziz, Al-Shuaibi 한국산업정보응용수학회 2000 한국산업정보응용수학회 Vol.4 No.1
A method for inverting the Laplace transform is presented, using a finite series of the classical Legendre polynomials. The method recovers a real-valued function f (t) in a finite interval of the positive real axis when f (t) belongs to a certain class W_(β) and requires the knowledge of its Laplace transform F(s) only at a finite number of discrete points on the real axis s > 0. The choice of these points will be carefully considered so as to improve the approximation error as well as to minimize the number of steps needed in the evaluations. The method is tested on few examples, with particular emphasis on the estimation of the error bounds involved.
Detection and Real-Time Monitoring of LDL-Cholesterol by Redox-Free Impedimetric Biosensors
Abdulaziz K. Assaifan,Fatimah A. Alqahtani,Sarah Alnamlah,Rasha Almutairi,Hend I. Alkhammash 한국바이오칩학회 2022 BioChip Journal Vol.16 No.2
In this work, non-faradaic impedimetric biosensor was developed for the direct detection of low-density lipoprotein (LDLcholesterol). Unlike other electrochemical techniques, non-faradaic electrochemical impedance spectroscopy (EIS) does not require the use of redox probes which denatures targeted biomarkers. Furthermore, no reference electrode is required for detection which is commercially viable. The biosensor reported here consists of LDL-antibodies attached to interdigitated gold electrodes via standard chemical functionalization. The biosensor demonstrated a sensitivity and limit of detection (LoD) of 70 nF/log(ng/mL) and 120 pg/mL, respectively, where the LoD is well below the recommended LDL level in blood. The biosensor also demonstrated good selectivity toward LDL. Thereafter we utilized, for the first time, the non-faradaic impedimetric biosensor for the continuous monitoring of LDL in phosphate buffer saline (PBS). The biosensor showed rapid responses to LDL injections. Such an approach is essential for the development of low-cost and scalable wearable biosensors for the direct real-time monitoring of chronic diseases and hence allows early medical interventions in cases where sudden increases in LDL or other biomarkers are deadly.