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Anticancer and Antioxidant Activity of Allergen-Removed Extract in Rhus verniciflua Stokes
Myongjokim,woncheolchoi,A.M.barshinikov,A.kobayashi 한국약용작물학회 2002 韓國藥用作物學會誌 Vol.10 No.4
Allergen-removed-extract was produced from Rush verniciflua by two phase methods. Phase one was high temperature treatment of Rush verniciflua tree to get allergen-removed-extract. Phase two was extraction of solution from phase one product using water or organic solvents. The solutions from above method show high antioxidant activity, anticancer activity, and improvement in lung function, but did not contain urushiol family compounds.
Inhibitory Effects of the Extract of Rhus verniciflua Stokes on the Reverse Transcriptase of AIDS
Myongjokim,woncheolchoi,A.M.barshinikov,A.kobayashi 한국약용작물학회 2002 韓國藥用作物學會誌 Vol.10 No.4
Four olefinic catechols, commonly referred to as urushiol were isolated from the sap of Korean Rhus verniciflua Stokes and had the stronger inhibitory effects on the reverse transcriptase of AIDS. The hexane extract with a inhibitory effects on reverse transcriptase was purified by silica and ODS gel column chronatography. The active compounds were identified by MS and ¹H-NMR as 3-[8'(Z), 11'(Z), 14'-pentadecatrienyl]catechol, 3-[8'(Z), 11'(Z)-pentadecadienyl]catechol, 3-[8' (Z)-penta- decenyl]catechol, and 3-pentadecylcatechol. All of these compounds showed strong inhibitory effects on reverse transcriptase of AIDS, in which 3-pentadecylcatechol exhibited the highest activity(IC50 : 10.87 ㎍/ml).
Anticancer and Antioxidant Activity of Allergen-Removed Extract in Rhus verniciflua Stokes
Kim, Myong-Jo,Choi, Won-Cheol,Barshinikov, A. M.,Kobayashi, A. The Korean Society of Medicinal Crop Science 2002 韓國藥用作物學會誌 Vol.10 No.4
Allergen-removed-extract was produced from Rush verniciflua by two phase methods. Phase one was high temperature treatment of Rush verniciflua tree to get allergen-removed-extract. Phase two was extraction of solution from phase one product using water or organic solvents. The solutions from above method show high antioxidant activity, anticancer activity, and improvement in lung function, but did not contain urushiol family compounds.
Inhibitory Effects of the Extract of Rhus verniciflua Stokes on the Reverse Transcriptase of AIDS
Myong-Jo Kim,Won-Cheol Choi,A. M. Barshinikov,A. Kobayashi 한국약용작물학회 2002 韓國藥用作物學會誌 Vol.10 No.4
Four olefinic catechols, commonly referred to as urushiol were isolated from the sap of Korean Rhus verniciflua Stokes and had the stronger inhibitory effects on the reverse transcriptase of AIDS. The hexane extract with a inhibitory effects on reverse transcriptase was purified by silica and ODS gel column chromatography. The active compounds were identified by MS and 1H-NMR as 3-[8' (Z), 11' (Z), 14' -pentadecatrienyl]catechol, 3-[8' (Z), 11' (Z)-pentadecadienyl]catechol, 3-[8' (Z)-penta- decenyl]catechol, and 3-pentadecylcatechol. All of these compounds showed strong inhibitory effects on reverse transcriptase of AIDS, in which 3-pentadecylcatechol exhibited the highest activity (IC50 : 10.87 μg/ml).
Inhibitory Effects of the Extract of Rhus verniciflua Stokes on the Reverse Transcriptase of AIDS
Kim, Myong-Jo,Choi, Won-Cheol,Barshinikov, A. M.,Kobayashi, A. The Korean Society of Medicinal Crop Science 2002 韓國藥用作物學會誌 Vol.10 No.4
Four olefinic catechols, commonly referred to as urushiol were isolated from the sap of Korean Rhus verniciflua Stokes and had the stronger inhibitory effects on the reverse transcriptase of AIDS. The hexane extract with a inhibitory effects on reverse transcriptase was purified by silica and ODS gel column chromatography. The active compounds were identified by MS and $^1H-NMR$ as 3-[8' (Z), 11' (Z), 14' -pentadecatrienyl]catechol, 3-[8' (Z), 11' (Z)-pentadecadienyl]catechol, 3-[8' (Z)-penta- decenyl]catechol, and 3-pentadecylcatechol. All of these compounds showed strong inhibitory effects on reverse transcriptase of AIDS, in which 3-pentadecylcatechol exhibited the highest activity $(IC_{50}\;:\;10.87\;{\mu}g/ml)$.
Anticancer and Antioxidant Activity of Allergen-Removed Extract in Rhus verniciflua Stokes
Myong-Jo Kim,Won-Cheol Choi,A. M. Barshinikov,A. Kobayashi 韓國藥用作物學會 2002 한국약용작물학회지 Vol.10 No.4
Allergen-removed-extract was produced from Rush verniciflua by two phase methods. Phase one was high temperature treatment of Rush verniciflua tree to get allergen-removed-extract. Phase two was extraction of solution from phase one product using water or organic solvents. The solutions from above method show high antioxidant activity, anticancer activity, and improvement in lung function, but did not contain urushiol family compounds.
Inhibitory Effects of the Extract of Rhus verniciflua Stokes on the Reverse Transcriptass of AIDS
Myong Jo Kim,Won Cheol Choi,A. M. Barshinikov,A. Kobayashi 한국약용작물학회 2002 한국약용작물학회지 Vol.10 No.4
Four olefinic catechols, commonly referred to as urushiol were isolated from the sap of Korean Rhus verniciflua Stokes and had the stronger inhibitory effects on the reverse transcriptase of AIDS. The hexane extract with a inhibitory effects on reverse transcriptase was purified by silica and ODS gel column chromatography. The active compounds were identified by MS and ^1H-NMR as 3-[8`(Z), 11`(Z), 14`-pentadecatrienyl]catechol, 3-[8`(Z),11`(Z)-pentadecatrienyl]catechol, 3-[8`(Z)-penta- decenyl]catechol, and 3-pentadecatrienyl. All of these compounds showed strong inhibitory effects on reverse transcriptase of AIDS, in which 3-pentadecatrienyl exhibited the highest activity(IC_50 : 10.87 ㎍/ml)./