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SBY-Ⅱ가 Zucker rats의 체중, 혈액 및 UCP mRNA 발현에 미치는 영향
이종수 ( Jong Soo Lee ),김도연 ( Do Yeon Kim ),정석희 ( Seok Hee Chung ),이종수 ( Jong Soo Lee ),김성수 ( Sung Soo Kim ) 한방재활의학과학회 2002 한방재활의학과학회지 Vol.12 No.2
Objective : This experimental study was designed to investigate the effect of SBY-Ⅱ extract on the weight, plasma, UCP mRNA in Zucker rats. Material and Methods : The body weight gain, weight of the internal organs(liver, adipose tissue), triglyceride, HDL-cholesterol, LDL-cholesterol, leptin, expression of UCP mRNA were measured in lean and obese(fa/fa) Zucker rats administered SBY-Ⅱ extract for 3 weeks. These were then compared with those of control groups administered physiological saline. Results : 1. In lean sample group, the body weight gain significantly decreased in the 3rd week(p<0.05). In obese sample group, the body weight gain decreased in the 3rd week. 2. In lean sample group, the weight of Liver, EWAT and RTWAT decreased, BAT increased in the 3rd week. In obese sample group, the weight of Liver, EWAT and RTWAT decreased, BAT significantly increased in the 3rd week(p<0.05). 3. In obese sample group, HDL-cholesterol significantly increased in the 3rd week(p<0.05). TG and LDL-cholesterol decreased in both lean and obese sample group. 4. In lean sample group, leptin decreased, whereas in obese sample group, leptin significantly increased in the 3rd week(p<0.05). 5. In lean sample group, the expression of UCP1 mRNA in BAT increased slightly. In obese sample group, the UCP1 mRNA in BAT highly expressed. Conclusion : These results shows that SBY-Ⅱ has effects on the management of obesity.
양하지 소력을 주소로 하는 길랑-바레 증후군 환자에 대한 한방치료 증례보고 1례
김고운,김성수,이종수,정석희,Kim, Koh-Woon,Kim, Sung-Soo,Lee, Jong-Soo,Chung, Seok-Hee 척추신경추나의학회 2011 척추신경추나의학회지 Vol.6 No.1
This study was performed to report the effectiveness of oriental medical treatment on a patient with Guillain-Barre syndrome complaining both lower extremity weakness. The patient was diagnosed as Guillain-Barre syndrome and treated with acupuncture, electroacupuncture, physical therapy and herbal medicine. We have evaluated the efficacy of oriental medical treatment by measuring changes of motor grade and ambulatory condition according to period of hospitalization. After treatment, motor grade and ambulatory condition were improved. These results suggest that oriental medical treatment was effective on the patient with Guillain-Barre syndrome.
하지 통증을 주소로 하는 대퇴골두 무혈성 괴사 환자에 대한 한방치료 증례보고 1례
김고운,김성수,이종수,정석희,Kim, Koh-Woon,Kim, Sung-Soo,Lee, Jong-Soo,Chung, Seok-Hee 척추신경추나의학회 2010 척추신경추나의학회지 Vol.5 No.1
대퇴골두 무혈성 괴사로 입원 치료한 환자 1례에 한방치료를 적용하여 하지 통증 감소와 고관절 ROM 증가에 유의한 효과를 보였기에 보고하는 바이다. This study was performed to report the effectiveness of oriental medical treatment on a patient with avascular necrosis of femur head complaining lower extremity pain. The patient was diagnosed as avascular necrosis of both femur head and treated with acupuncture, cupping therapy, physical therapy and herbal medicine. We have evaluated the efficacy of oriental medical treatment by measuring changes of visual analogue scale and range of motion according to period of hospitalization. After treatment, pain and range of motion were improved. These results suggest that oriental medical treatment was effective on the patient with avascular necrosis of femur head.
육미지황탕이 고압환경에 노출된흰쥐의 혈액조성에 미치는 영향
김성욱 ( Kim Sung-Uk ),정석희 ( Chung Seok-Hee ),이종수 ( Lee Jong-Soo ),김성수 ( Kim Sung-Su ),신현대 ( Shin Hyun-Dae ) 한방재활의학과학회 1997 한방재활의학과학회지 Vol.7 No.1
실험적 고압환경에 노출된 흰쥐에 육미지황탕을 각각 1회( Sample A), 2주일간(Sample B), 4주일간(Sample C)투여한 다음 혈액학적 변화와 혈액 가스 분포에 미치는 영향을 살펴본 바 다음과 같다.1. 혈소판은 Sample A에서 모두 감소 하였으며, 헤모글로빈은 Sample B 2기압군에서, 적혈구는 Sample A 2기압군에서 감소하였다. 그리고 헤마토크리트는 Sample B 3기압군과 Sample C 2기압군에서 증가하였다.2. 평균혈구용적 (MCV)은 Sample A 2기압군과 Sample B 2기압군에서 증가하였으며, 평균혈구 혈색소량 (MCH)은 Sample B 3기압군에서 그리고 평균혈구 혈색소농도 (MCHC)는 Sample B군 모두에서 감소하였다.3. pH는 Sample C 2기압군에서, Po2는 Sample C 군 모두에서 증가하였고, Pco2는 Sample C 2기압군과 Sample A 3기압군에서 감소하였다. 그리고 HCO3-는 Sample A 2기압군에서 감소하였다.4. BE는 Sample A군에서 모두 감소하였고, O2 SAT는 Sample B군에서 모두 증가하였다. 그리고 O2 CT는 유의성있는 변화가 없었다.