가열온도(加熱溫度)에 따른 애엽(艾葉)의 성분변화(成分變化) 및 생리활성(生理活性)에 관(關)한 연구(硏究)

박영재,박영배,김용석,고형균,김창환,강성길,Park Young-Jae,Park Young-Bae,Kim Yong-Suk,Koh Hyung-Kyun,Kim Chang-Hwan,Kang Sung-Keel 대한침구의학회 1998 대한침구의학회지 Vol.15 No.2

Purpose : The study for changes in components and acitvities of Artemisiae Herba at various processing temperature is generally regarded as a foundation in setting the optimum heat-processing temperature and for getting the maximum activities for medical usage of this herb. Methods: Therefore some experiments were performed either in vitro or in vivo and various changes were observed - the changes in the weitht of Artemisiae Herba, the changes in the relative amount of three kinds of extracts from Artemisiae Herba ( diluted ethanol extract, water extract, ether extract ), the TLC pattern of essential oil at various processing temperature, the existance of inhibitory effects both on ${\beta}$-Glucuronidase activities, and on heat-induced hemolysis, the effects on increased vascular permeability. The valid results derived from the experiments are as follows. Results: 1. The weight of Artemisiae Herba prominently decreased at 240^{\circ}C$. 2. The contents of diluted ether extract were maximum in the unprocessing condition. Those of water extract were maximum at 180^{\circ}C$ and at 210^{\circ}C$. and the changes of diluted ethanol extract at 150^{\circ}C$. 3. The TLC pattern of essential oil in Artemisiae Herba at various processing temperature showed that a component began to increase at Rf 0.56 and another component began to decrease at Rf 0.86. 4. The contents of Eupatilin in Artemisiae Herba at various processing temperature continued to decreased in proportion to the temperature rise, the extent of which was prominent at 210^{\circ}C$, and was unnoticeable at 270^{\circ}C$. 5. Inhibitory effects on ${\beta}$-Glucuronidase activities, trypsin activities and heat-induced hemolysis increased in proportion to the density of Artemisiae Herba. Inhibitory effects on ${\beta}$-Glucuronidase activities and trypsin activities were relatively high at 180^{\circ}C$ while on the writhing syndrome and inhibitory effects on increased vascular permeability induced by acetic acid were maximum at 240^{\circ}C$. those on heat-induced hemolysis were relatively high at 240^{\circ}C$. 6. In vivo, both analgesic effects Conclusions: To maximize of the effectiveness of Artemmisiae Herba, the ideal heating temperature is in the range of 180^{\circ}C{\sim}240^{\circ}C$.

무정형 알루미나에서의 Ni(II), Co(II), Sr(II) 흡착의 표면착물 모델링

박영재,박경균,서무열,윤수경,최광순,지광용,김원호,Park, Yeong Jae,Park, Kyoung Kyun,Suh, Moo Yul,Yoon, Soo Kyoung,Choi, Kwang Soon,Jee, Kwang Yong,Kim, Won Ho 대한화학회 2000 대한화학회지 Vol.44 No.4

일정한 이온강도(0.1M)에서 알루미나에 의한 Ni(II), Co(II), Sr(II) 및 Cs(I)의 흡착거동을 세 가지의 금속이온 농도를 사용하여 pH를 변화시키면서 관찰하였다. 금속 이온의 농도가 증가할수록 흡착률은 감소했으며 흡착변곡점이 보다 높은 pH쪽으로 이동하였다. 금속 이 온의 농도가 $1.0{\times}10^{-4}$M인 조건에서 측정한 흡착데이터로부터 표면착물 모델을 적용하여 각 금속의 흡착종에 대한 고유의 흡착상수 값을결정하였다. 흡착 세기는 Co(II)>Ni(II)>Sr(II)순으로 감소하였으며 Cs(I)는 흡착이 되지 않았다. 높은 pH에서의 Co(II)와 Ni(II)의 흡착성이 대부분이 가수분해된 형태로 존재하였다. Adsorpdon behaviors ofNi(II), Co(II), Sr(II), and(I) ions were nvestigated on amorphous alumina with varying pH at three different etalion concentrations under the condition of 0.I M ionlc strength.With increasingmctalion concentration, the percentage of adsorption decreased and the adsorption edge was shifted to a higher pH value. The adsorption data obtained usingthe metal ion concentration of $1.0{\times}10^{-4}$M were quantitatively analyzed by surfacecomplexation modelingof Ni(II) and Co(II) ions adsorbed at high pH (>8)were found to be in hydrolyzed forms.

무정형 알루미나에서의 니켈(II) 이온의 흡착에 관한 연구

박영재,서무열,박경균,최광순,지광용,김원호,Park, Yeong Jae,Suh, Moo Yul,Park, Kyoung Kyun,Choi, Kwang Soon,Jee, Kwang Yong,Kim, Won Ho 한국분석과학회 2000 분석과학 Vol.13 No.4

무정형 알루미나를 흡착제로 사용하여 니켈(II) 이온의 흡착거동을 조사하였다. 흡착반응속도에 관하여 실험한 결과, 두 단계 흡착, 즉 한 시간 이내 빠르게 진행되는 흡착과 그 이후에는 느리게 진행되는 흡착으로 구분되었다. 흡착등은 실험에서는 Langmuir-Freundlich 흡착식을 만족하였으며 PH가 높을수록 최대흡착량이 증가함을 보였다. 이온강도의 변화에 따른 흡착량의 변화를 조사한 결과 어떤 뚜렷한 경향성을 보이지 않은 것으로 보아 니켈(II) 이온의 흡착은 정전기적 상호작용이라기 보다는 표면착물형성으로 이루어짐을 추정할 수 있었다. 일정한 이온강도에서 세 가지의 니켈(II) 이온 농도에서 pH를 변화시키면서 흡착량을 측정한 결과 니켈(II) 이온의 농도가 높을수록 흡착률은 감소했으며 흡착변곡점은 보다 높은 pH쪽으로 이동하였다. Adsorption behaviors of Ni(II) ions were investigated using amorphous alumina as adsorbent. In the adsorption kinetic study, it was observed that Ni(II) ions were bound to the alumina surface in two adsorption stages, the rapid and slow adsorption stages. The rapid adsorption proceeded within 1 hr, thereafter the slow adsorption occurred. The results of adsorption isotherm experiments showed that the Ni(II) adsorption obeyed the Langmuir-Freundlich isotherm, and that the adsorption enhanced with increasing pH. The change in ionic strength did not exhibit a conspicuous trend in Ni(II) adsorption, thereby suggesting that the adsorption occurs through surface complexation rather than electrostatic interactions. The amounts of adsorption were measured with varying pH at three different Ni(II) concentrations under the condition of constant ionic strength, showing that with increasing Ni(II) concentration, the percentage of adsorption decreased and the adsorption edge was shifted to a higher pH value.

IPMSM 회전자 스큐 각도 산정 방식에 따른 성능분석

박영재(Young-Jae Park),김용재(Yong-Jae Kim),정상용(Sang-Yong Jung) 대한전기학회 2017 대한전기학회 학술대회 논문집 Vol.2017 No.4

[화학] 무정형 알루미나에서의 니켈(Ⅱ) 이온의 흡착에 관한 연구

박영재(Yeong Jae Park),서무열(Moo Yul Sub),박경균(Kyoung Kyun Park),최광순(Kwang Soon Choi),지광용(Kwang Yong Jee),김원호(Won Ho Kim) 한국분석과학회 2000 분석과학 Vol.13 No.4

맥솔(脈率)과 체성분(體成分) 분석(分析)의 상관성(相關性) 연구(硏究)

박재성 ( Jae-sung Park ),박영배 ( Young-bae Park ),김민용 ( Min-yong Kim ),박영재 ( Young-jae Park ) 대한한의진단학회 2006 大韓韓醫診斷學會誌 Vol.10 No.2

Objectives: The objective is that we measure and analyze Pulse-Respiration Ratio and Body Composition Analysis to study the correlation between both. Methods: First, after subjects take a rest over 10 minutes, we measure their electrocardiogram and respiration pattern through which we take average peak interval to calculate an average pulse cycle and a respiration cycle. An average respiration cycle divided by an average Pulse Rate gives Pulse-Respiration Ratio. Next, we draw out 22 Body Composition Analysis indicators by using In-Body 720 model. Last, we analyze and take statistics on them by using SPSS 13.0 program. Results: Negative is the correlation between P/R Ratio and Body Composition Analysis indicator like fatness degree, body fat volume, body fat rate, abdominal fatness, HMI. Conclusions: 1. The higher P/R Ratio the more likely to be thin, the lower P/R Ratio the more likely to be fat. 2. We separately analyze P/R Ratio depending on each breathing frequency and pulse frequency to find out that breathing frequency has great influence and that breathing frequency decides the fatness degree. 3. In study on the correlation between P/R Ratio and Body Composition Analysis, fatness degree, in-body fat volume, in-body fat rate, HMI are the related indicators, which shows the connection with the fatness indicators. 4. In study on the correlation between Han-Yeol (寒熱) grade and Body Composition Analysis indicators, the result is that Han[寒] has no connection and that only Yeol [熱] grade has something to do with it, which means the higher heat symptom subjects have, the more basic metabolism volume and muscular build they have.

담음변증(痰飮辨證) 설문(說問) 개발(開發)을 의한 문헌연구(文獻硏究)

박재성 ( Jae-sung Park ),김민용 ( Min-yong Kim ),박영재 ( Yong-jae Park ) 대한한의진단학회 2006 大韓韓醫診斷學會誌 Vol.10 No.1

Objectives: In this study a pattern questionnaire for damum patterns was developed by means of literature review and statistical analysis. The individual approach of korean medicine is based on the concept of pattern identification, the objectivity and validity issues of which hold important meaning in the pratice and research. Methods: Review of literatures led to the selection of 22 items describing Dam or Urn pattern. A preliminary questinnaire consisted of these items that may be scored with positive score at zero to seven. Results: Damum is all over the body syndromes. That is abnormal body conditions. Damun arouse body pain, breath disorder, digestion disorder, nerves disorder, excretion disorder. Conclusions: Review of literatures led to selection of 29 items describing Damun. A questionnaire is in preparation.

痰飮辨證 說問 開發

박재성 ( Jae-sung Park ),양동훈 ( Dong-hoon Yang ),김민용 ( Min-yong Kim ),이상철 ( Sang-chul Lee ),박영재 ( Yong-jae Park ) 대한한의진단학회 2006 大韓韓醫診斷學會誌 Vol.10 No.1

Objectives Damum is a general and fundamental concept in Oriental medicine that deals with symptoms of diseases. but as far as Damum is concerned there has not been significant researches in terms of clinical medicine but only researches in the field of medical history. Therefore hopefully this study could contributes to the development of Damum which is very essential concept in Oriental medicine. Methods First of all we have made basic twenty-three items list through conducting researches on documents in regards to Damum, and finally designed twenty-nine survey inquiry by so called Delphi study-method that is based on opinions of professional groups. we have conducted a survey of twenty-nine inquirys on sixty-one cases and asked three Oriental medical doctors who are Damum specialists to diagnose and measure clinical values regarding Damum, followed by studying interrelationship between survey results and clirucal values. conclusively we have made out a final Damum questionnaire form by selecting Significant question items based on the results of the study. Results According to the analysis of the studies, fourteen question items were selected. Conclusions As far as Damum discriminant is concerned, additional verifing processes are needed to be carried out through more clinical cases. And it is thought that more clinical studies are needed to be done in regards to Damum.

8체질의학에 대한 환자 인식 조사

박재성 ( Jae-sung Park ),박영재 ( Young-jae Park ),민재영 ( Jae-young Min ),신용섭 ( Yong-sup Shin ),이상철 ( Sang-chul Lee ),박영배 ( Young-bae Park ),김민용 ( Min-yong Kim ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.1

Background and purpose: The purpose of this study is to search recognition patients in Eight constitution Oriental Medical Clinic. And we compare Eight constitution acupuncture methods with the another acupuncture methods. Methods: The subjects were comprised of 200 volunteers. In 3 Eight constitution Oriental Medical Clinic participants were chosen through questionnaire. Finishing answer participants put in their lacked name questionnaire to gathering box. DecisionTree (AnswerTree 3.0 Ver.) statistical software was used for statistical analysis. Results and Conclusion: As a result of the analysis of cognition to Eight constitution acupuncture methods was influenced to patients health, dietetic therapy is best influenced. Next influenced acupuncture reflex degree, age, job, constitution, cure periods, sex distinction, cure degree, diagnosed participant`s Constitution by pulse diagnosis in 8 Constitution Medicine.

팔체질침 전문 한의사의 체질침 효과에 대한 인식조사

민재영 ( Jae-young Min ),박영재 ( Young-jae Park ),박재성 ( Jae-sung Park ),신용섭 ( Yong-sup Shin ),박영배 ( Young-bae Park ),이상철 ( Sang-chul Lee ),김민용 ( Min-yong Kim ) 대한한의진단학회 2007 大韓韓醫診斷學會誌 Vol.11 No.1

Objectives: The purpose of this research is to obtain basic data about the effects of Constitution-Acupuncture (CA) based on Eight-Constitution Medicine (ECM) by the expert CA Oriental Medical Doctors. Methods: The resources were collected from the internet survey method. 35 samples were collected. The SPSS 13.0 for windows and Answer Tree 3.0 was used for statistical analysis. Results: The results from this research are as follow. 1. The motivation that apply ECM to clinic are `Because ECM is effective for diagnosis, treatment and prevention against disease` 48.6% and `Because CA therapy is effective` 25.7%. 2. The advantage that CA therapy compare to the other acupuncture therapy are `Management and prevention against disease are available by ECM theory to a person who exact constitution is confirmed` 82.9%, `CA therapy is superior in treatment of hard symptoms to treat by the other acupuncture therapy` 80%, `Treatment effect is good` 77.1%, `Needle manipulation of CA is simple comparatively` 57.1%, `It is definite whether treatment effect is good or not` 54.3% and CA therapy is superior all in diseases of twelve category. 3. When the effects of CA is good, patients expressed much `Eyesight lightened`, `Took deep sleep at night`, `Fatigue decreased`, `Body is light`, `Feelings became refreshing` as well as `Symptoms were improved` and also physicians confirmed as those reactions whether treatment is effective. Conclusions: The research suggest that CA is effective therapy in clinic, and so further study is needed for CA therapy.