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Sucralfate 가 흰쥐의 위 당단백 및 Somatostatin 에 미치는 영향
김종숙(Chong Suk Kim),김영수(Young Soo Kim),이인덕(In Deog Lee),안장훈(Jang Hoon Ahn),장세경(Sae Kyuong Chang),유병철(Byeong Chul Yoo),박실무(Sil Mu Park) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
To clarify the effect of sucralfate on glycoprotein and somatostatin, this study was performed with the use of Wistar rat and measuring the concentration of glycoprotein and somatostatin, using radioimmunoassay kits. The result were as follows; 1) In determination of ulcer index, there could be showed the increase in the sucralfate group as compared with the ulcer group (2.20+-1.94, p<0.01). In gastric pH, there could be demonstrated the ulcer group as compared with the control group. 2) In determination of Alcian blue-binding protein of soluble mucus, there could be demonstrated the increase in the sucralfate group as compared with the ulcer group (0.23+-0.07 mg/5 ml, 0.67+-0.03 mg/5 ml, p < 0.05). 3) The concentration of plasma somatostatin revealed the increase in the sucralfate group as compared with the ulcer group and control group (p<0.001). 4) The concentration of somatostatin of gastric juice revealed the increase in the sucralfate group and the ulcer group as compared with the control group respectively (p<0.001). 5) The concentration of somatostatin of gastric mucosa revealed the increase in the sucralfate group as compared with the control group and the ulcer group respectively (p<0.001, p<0.01).
궤양 치료제와 Aspirin 에 의한 흰쥐의 벽세포 및 주세포의 변화
김종숙(Chong Suk Kim),이인덕(In Dong Lee),이영갑(Yong Gap Lee),장세경(Sai Kyung Chang) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1
N/A The present study was carried out to assess the effect on parietal cell and chief cell after ranitidine, pirenzepine, and aspirin administration in rats. The following results were obtained: 1) In the average corrected No. of parietal cells per unit area and parietal cell population, ranitidine group was increased compared with control, aspirin and aspirin with ranitidine group in single and multiple injection. 2) In the average corrected No. of parietal cells per unit area, aspirin group was decreased compared with control and ranitidine group in single injection. 3) In the average corrected No. of chief cells per unit area and chief cell population, ranitidine group was increased compared with control group in single and ranitidine group was increased compared with control and aspirin with ranitidine group in multiple injection. 4) In the parietal cell population, ranitidine and pirenzepine group were increased compared with control and aspirin group in multiple injection.
전철웅(Cheol-woong Jeon),김종숙(Chong Suk Kim) 한국중원언어학회 2016 언어학연구 Vol.0 No.38
The purpose of this study was to explore the historical development of 56 words beginning with ‘ㄱ(k), ㄴ(n), ㄷ(t), ㅁ(m),’ which are registered in Chungcheongbuk-do dialect, focusing on the investigation of morphological and phonological changes of the 56 words selected. On the developmental stages, the 56 words clearly went through various phonological changes as follows: word-initial tensification of ‘ㄱ(k)(6)’, ‘ㄷ(t)(2)’, word-final aspiration of ‘ㄷ(t)(1), ㅈ(č)(1)’, palatalization of ‘ㅅ(s)(1), ㅈ(ts)(6), ㅊ(ts<SUP>h</SUP>)(1)’ & ‘ㅌ(t<SUP>h</SUP>)(1)’, an addition of word-final ‘ㄹ(l)(1)’ & ‘ㅎ(h)(1)’, a deletion of intervocalic ‘ㅎ(h)(1)’ & word-final ‘ㅎ(h)(3)’, a deletion of ‘ㅂ(p)’ in front of ‘ㅺ(k’)(1), ‘ㅈ(ts)(1) & ‘ㄷ(t)(7)’, umlaut of ‘ㅏ(a)(3)’, monophthongization(⓵ay>ɛ(8), ⓶əy>e(1), ⓷oy>ö(1), ⓸uy>ü(1), ⓹ɨy>i(3)), vowel rounding (ɨ>u)(5), vowel raising(o>u)(2), a first step change of ‘오(ʌ)(⓵ʌ>ɨ)(7), ⓶ʌ>o(1)), a second step change of ‘오(ʌ)(ʌ>a)(14), an addition of glide ‘ㅣ(y)(o>oy)(1)’, a deletionof glide ‘ㅣ(y)’(①redundant feature ‘y’ in front of palatal consonants ‘ㅅ(1), ㅈ(1)’, ⓶off-gliding ‘y’(1)), and so on. In addition to these findings, this study in depth discussed some other interesting findings in relevance to the historical development of the 56 words.
임신후기(姙娠後期)에 발생(發生)한 급성간지방변성(急性肝脂肪變性)
정규원,정환국,안영설,김종숙 대한소화기학회 1968 대한소화기학회지 Vol.1 No.1
A case report of a 23 year-old pregnant woman with the clinical, laboratory and pathologic features consistent with acute fatty metamorphosis of the liver in pregnant woman is presented. She delivered a viable premature female infant and healthy in both, and the literatures were reviewed. This is the 7th patient survived and only the 4th case with survival of mother and child without the use of tetracycline, added to our case in the literatures. This patient was treated for acute pyelonephritis and there was no evidence of acute pancreatitis or severe renal insufficiency. In the present case, the onset of illness and jaundice appeared earlier than the reported cases and there was severe vaginal bleeding after the premature delivery. The pathologic findings were morphologically characterized by a foamy cell type of fatty metamorphosis of all the hepatic lohules, accompanied by some mononuclear infiltrates around the periportal areas without necrosis. Liver neddle biopsy is essential. For the diagnosis of this disease, and the prognosis depends upon vigorous supportive treatments based on early suspicion and diagnosis.