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Tuncay Hazirolan,Baris Turkbey,Erhan Akpinar,Murat Canyigit,Musturay Karcaaltincaba,Bora Peynircioglu,Z. Dicle Balkanci,Deniz Akata,Ferhun Balkanci 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.2
Objective: This study was designed to investigate the effect of administration of warmed contrast material (CM) on the bolus geometry and enhancement as depicted on coronary CT angiography. Materials and Methods: A total of 64 patients (42 men, 22 women; mean age, 56 years) were randomly divided into two groups. Group 1 included 32 patients administered CM (Omnipaque [Iohexol] 350 mg I/ mL; Nycomed, Princeton, NJ) saline solutions kept in an incubator at a constant temperature (37℃). Group 2 included 32 patients administered the CM saline solutions kept at constant room temperature (24℃). Cardiac CT scans were performed with a dual source computed tomography (DSCT) scanner. For each group, region of interest curves were plotted inside the ascending aorta, main pulmonary artery and descending aorta on test bolus images. Using enhancement values, time/enhancement diagrams were produced for each vessel. On diagrams, basal Hounsfield unit (HU) values were subtracted from sequentially obtained values. A value of 100 HU was accepted as a cut-off value for the beginning of opacification. The time to peak, the time required to reach 100 HU opacification, maximum enhancement and duration of enhancement above 100 HU were noted. DSCT angiography studies were evaluated for coronary vessel enhancement. Results: Maximum enhancement values in the ascending aorta, descending aorta and main pulmonary artery were significantly higher in group 1 subjects. In the ascending aorta, the median time required to reach 100 HU opacification during the test bolus analysis was significantly shorter for group 2 subjects than for group 1 subjects. In the ascending aorta, the descending aorta and main pulmonary artery, for group 1 subjects, the bolus geometry curve shifted to the left and upwards as compared with the bolus geometry curve for group 2 subjects. Conclusion: The use of warmed CM yields higher enhancement values and a shorter time to reach maximum enhancement duration, resulting in a shift of the bolus geometry curve to the left that may provide optimized image quality. Objective: This study was designed to investigate the effect of administration of warmed contrast material (CM) on the bolus geometry and enhancement as depicted on coronary CT angiography. Materials and Methods: A total of 64 patients (42 men, 22 women; mean age, 56 years) were randomly divided into two groups. Group 1 included 32 patients administered CM (Omnipaque [Iohexol] 350 mg I/ mL; Nycomed, Princeton, NJ) saline solutions kept in an incubator at a constant temperature (37℃). Group 2 included 32 patients administered the CM saline solutions kept at constant room temperature (24℃). Cardiac CT scans were performed with a dual source computed tomography (DSCT) scanner. For each group, region of interest curves were plotted inside the ascending aorta, main pulmonary artery and descending aorta on test bolus images. Using enhancement values, time/enhancement diagrams were produced for each vessel. On diagrams, basal Hounsfield unit (HU) values were subtracted from sequentially obtained values. A value of 100 HU was accepted as a cut-off value for the beginning of opacification. The time to peak, the time required to reach 100 HU opacification, maximum enhancement and duration of enhancement above 100 HU were noted. DSCT angiography studies were evaluated for coronary vessel enhancement. Results: Maximum enhancement values in the ascending aorta, descending aorta and main pulmonary artery were significantly higher in group 1 subjects. In the ascending aorta, the median time required to reach 100 HU opacification during the test bolus analysis was significantly shorter for group 2 subjects than for group 1 subjects. In the ascending aorta, the descending aorta and main pulmonary artery, for group 1 subjects, the bolus geometry curve shifted to the left and upwards as compared with the bolus geometry curve for group 2 subjects. Conclusion: The use of warmed CM yields higher enhancement values and a shorter time to reach maximum enhancement duration, resulting in a shift of the bolus geometry curve to the left that may provide optimized image quality.
( Tolga Yildirim ),( Hadim Akoglu ),( Rahmi Yilmaz ),( Gonca Eldem ),( Tuncay Hazirolan ),( Tuncay Aki ),( Mustafa Arici ),( Bulent Altun ),( Yunus Erdem ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Immunosuppressive protocols decreased the rates of acute rejection in kidney transplantation however long term graft survival has not changed signifi cantly. Nephron underdosing may be one of the factors affecting the long term prognosis of the transplanted kidney. Aim of this study was to determine the impact of volume of transplanted kidney on long term allograft functions. Methods: The study was conducted among sixty-two living renal transplant recipients (41 male, 21 female; mean age 30.6±10.2 years) who underwent transplantation between years 2003-2007 and their respective donors (22 male, 40 female; age 41.9±9.9 years). Patients that suffered graft loss due to any cause within fi ve years after transplantation were excluded. Volume of the transplanted kidneys had been measured preoperatively via 3-D helical computerized tomography. Transplanted kidney volume/ recipient weight (Vol/weight) was calculated for each donor-recipient pair. Subjects were divided into two groups according to the median value of Vol/weight (2.35 cm3/ kg). Glomerular fi ltration rates (GFR) of the recipients were calculated for fi ve years. Results: First and third year GFR`s of the patients was significantly higher in Vol/ weight>2.35 cm3/kg group compared to Vol/weight<2.35 cm3/kg group (73.7±17.6 vs. 61.6±19.3, p=0.01 and 72.3±20.7 vs. 60.0±17.3, p=0.01 respectively). However fi fth year GFR was similar in both groups (64.5±16.9 and 56.6±21.7, p=0.11). There was a signifi cant correlation between Vol/weight and both fi rst and third year GFR`s (r=0.409, p<0.001 and r=0.429, p<0.001; respectively). The correlation was not observed with the fi fth year GFR (r=0.133, p=0.303). Conclusions: Volume of transplanted kidney adjusted for recipient weight is a signifi - cant predictor of early but not late graft functions.