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A Case of Adult Onset Still`s Disease Misdiagnosed as Septic Arthritis
( Sang Jun Song ),( Dae Kyung Bae ),( Jung Ho Noh ),( Geon Wook Seo ),( Dong Cheol Nam ) 대한슬관절학회 2011 대한슬관절학회지 Vol.23 No.3
We present a case of adult onset Still`s disease (AOSD) that was misdiagnosed as septic arthritis of the shoulder and knee. A forty-nine-year-old woman was admitted for pain in the left knee. The patient`s medical history showed that she had undergone arthroscopic irrigation twice and an open debridement under the diagnosis of septic shoulder at another hospital. The laboratory and joint fluid analysis findings led us to suspect septic knee. Arthroscopic irrigation and antibiotics treatment were performed. At five weeks after discharge, she presented with pain in the same joint, fever, and rash. The symptoms were consistent with Yamaguchi`s criteria for AOSD. We started corticosteroid therapy, and clinical remission was achieved. In conclusion, we suggest that AOSD should be considered as a diagnosis of exclusion to avoid misdiagnosis with septic arthritis.
Sang Jun Song,Cheol Hee Park,Jong Whan Lee,Hyun Woo Lee,Kand Il Kim,Dae Kyung Bae 대한정형외과학회 2023 Clinics in Orthopedic Surgery Vol.15 No.1
Background: Patella baja with patellar tendon shortening due to traumatic or ischemic injury is a widely known complication after primary total knee arthroplasty (TKA). Pseudo-patella baja may arise from the elevation of the joint line after excessive distal femoral resection. The maintenance of original patellar height is important in revision TKA because postoperative patella baja and pseudo-patella baja can cause inferior biomechanical and clinical results. We investigated the incidence and risk factors of patella baja and pseudo-patella baja after revision TKA. Methods: We retrospectively reviewed data for 180 revision TKAs. Patella baja was defined as a truly low-lying patella with an Insall-Salvati ratio (ISR) of < 0.8 and a Blackburne-Peel ratio (BPR) of < 0.54. Pseudo-patella baja was defined as a relatively lowlying patella compared to the joint line within the normal range of ISR and with a BPR of < 0.54. Clinically, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and range of motion (ROM) were evaluated. Risk factors increasing the incidence of patella baja and pseudo-patella baja after revision TKA were evaluated using multiple regression analysis. Results: Before revision TKA, 169 knees did not exhibit patella baja or pseudo-patella baja, while 9 knees showed patella baja and 2 knees exhibited pseudo-patella baja. At 2 years after revision TKAs, 25 knees (13.9%) showed patella baja and 23 knees (12.8%) exhibited pseudo-patella baja. Despite no differences in the postoperative WOMAC score between groups with and without patella baja and pseudo-patella baja, the postoperative ROM was significantly smaller in the group with patella baja (113.3°) or pseudo patella baja (110.5°) than in the normal group (122.0°). Infection as the cause of revision TKA increased the risk of patella baja (odds ratio, 10.958; p < 0.001), and instability increased the risk of pseudo-patella baja (odds ratio, 11.480; p < 0.001). Conclusions: Infection and instability resulted in increases in the incidence of patella baja and pseudo-patella baja after revision TKA. Information about the risk factors of patella baja and pseudo-patella baja will help TKA surgeons plan the height of the patella after revision TKA and improve clinical outcomes.
Proteomic Analysis of Seed Storage Proteins in Low Allergenic Soybean Accession
( Sung Cheol Koo ),( Dong Won Bae ),( Jun Su Seo ),( Kyoung Mi Park ),( Man Soo Choi ),( Seok Hyeon Kim ),( Sang In Shim ),( Kyeong Moon Kim ),( Jong Il Chung ),( Min Chul Kim ) 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.3
Soybean (Glycine max L. Merr.) is a major source of protein for human and animal nutrients. However, soybean seed also contains a number of allergenic proteins, which limit its extensive usage in the food industry. P34 (Gly m Bd 30K), a low-leveled but highly conserved seed storage protein, has been described as a major allergen in soybean seed. Recently, two low P34 soybean accessions, PI603570A and PI567476, were identified by extensive screening of soybean germplasm. We have surveyed spatiotemporal expression pattern of P34 protein in low P34 accession, PI567476, and cultivated soybean accession, Clark, using antibody against P34. Immunoblot analysis showed not only seed specific expression pattern of P34, but also significantly reduced expression of P34 in PI567476 compared to Clark. Additionally, we performed proteomic analysis to compare protein compositions between PI567476 and Clark accessions. Although the overall distribution pattern of the protein spots was similar in both soybean accessions, 19 protein spots showing different intensity between both accessions were detected and analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF/MS). PI567476 accession exhibited altered expression of several seed storage proteins including allergens and seed maturation-related proteins. The detailed analysis for composition of seed storage proteins of the PI567476 accession provides valuable information in use of this soybean germplasm for breeding of low allergenic elite soybean lines, which is expected to enhance food safety and make soy products available to allergen-sensitive individuals.
Bae, Hong-Chul,Hong, Seri,Jang, Sung-In,Lee, Kwang-Sig,Park, Eun-Cheol The Korean Society for Preventive Medicine 2015 예방의학회지 Vol.48 No.3
Objectives: The purpose of this study was to investigate the association between suicidal behavior and patterns of alcohol consumption in Korean adults. Methods: This study was based on data provided by the Korea National Health and Nutritional Examination Survey from 2007 to 2011. A total of 42 347 subjects were included in the study, of whom 19 292 were male and 23 055 were female. Logistic regression analysis was performed to assess the association between patterns of alcohol consumption and suicidal behavior. Results: Among the study subjects, 1426 males (11.3%) and 3599 females (21.2%) had experienced suicidal ideation, and 106 males (0.8%) and 190 females (1.1%) had attempted suicide during the previous 12 months. Alcohol Use Disorders Identification Test (AU-DIT) scores were found to be associated with suicidal ideation in males and associated with both suicidal ideation and suicide attempts in females. Alcoholic blackouts were associated with suicidal ideation and suicide attempts in males, and were also associated with suicidal ideation in females. Conclusions: In this study, we found that certain patterns of alcohol consumption were associated with suicidal behaviors. In particular, only alcoholic blackouts and categorized AUDIT scores were found to be associated with suicidal behavior in males. We therefore suggest that further research is needed to examine this relationship prospectively and in other settings.
Bae, Jae Kwan,Kim, Hyun-Woo,Accardo, Grazia,Kim, Ghun Sik,Ham, Hyung Chul,Jang, Seong-Cheol,Cho, Yong Soo,Yoon, Sung Pil Elsevier 2019 International journal of hydrogen energy Vol.44 No.47
<P><B>Abstract</B></P> <P>Molten carbonate fuel cells (MCFCs) are regarded as the closest fuel cell to commercialization due to their high capacity and energy efficiency. However, they are operated at a high temperature (620 °C or higher), where liquid electrolyte loss occurs during operation; hence, their lifetime is limited. For the long-term operation of MCFCs, it is essential to develop a novel method to replenish the electrolyte during operation. However, it is very difficult to directly inject the electrolyte, (Li<SUB>0.62</SUB>K<SUB>0.38</SUB>)<SUB>2</SUB>CO<SUB>3</SUB>, into each unit cell of the stack unless it is supplemented through liquid or gas phase at low temperature. It was verified whether LiI and KI, which have low melting points and high vapor pressures, could replenish the lost electrolyte in MCFCs. In this study, the LiI and KI injected into the unit cell in liquid phase showed a similar tendency to the Li/K carbonate electrolyte. This is because LiI and KI react with the CO<SUB>2</SUB>/O<SUB>2</SUB> gases supplied to the cathode during MCFC operation to form Li/K carbonate electrolytes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Electrolyte precursors (LiI and KI) were selected by thermodynamic calculation. </LI> <LI> LiI and KI with low melting temp. are suitable for electrolyte replenishment. </LI> <LI> LiI and KI supplements are effective in ensuring stable performance for MCFCs. </LI> </UL> </P>