비스테로이드성 항염제(NSAIDs : Ibuprofen)가 가토의 악관절 치유와 골개조에 미치는 영향에 관한 연구

임한욱,김경욱,임창준 단국대학교 치의학연구소 1993 논문집 Vol.5 No.-

The purpose of this experiments was to study the effect of NSAIDs on the healing and remodeling of bone and cartilage in the temporomandibular joint of the rabbits. Fifteen rabbits were operated to create a groove and a hole in the articular surface of both the right and the left mandibular condyles. After surgery, operated animals were divided into three groups. Group A (5 rabbits) which did not take any medication was control group. Group B (5 rabbits) was given a daily dose of 17.0 mg/kg of ibuprofen. Group C (5 rabbits) was given a daily dose of 34.0 mg/kg of ibuprofen. Animals were killed on post-operative 1, 3 days, 1, 2 and 4 weeks. The 30 condyles were examined radiographically and histo logically. The results were as follows : 1. There was no significant difference between two medication groups. 2. Granulation tissue, osteoid tissue and trabecular pattern formation appeared on post-operative 1 week and osteoblasts activity was less active than the control group. 3. The infiltration of inflammatory cells decreased at the 3rd day and could not find them at two weeks. 4. The degree of bony sclerosing effect was less than the control group by means of soft X-ray.

정상 및 당뇨병 환자에서 포도당 정주에 따른 혈중 포도당과 인슐린 반응에 관한 연구

임경호,구도서,유동준,최영길 대한의학협회 1990 대한의학협회지 Vol.33 No.9

열성화상으로 인한 상후두부 통증에서 상후두신경차단의 진통효과 : 증례보고

임경준,이재황,고우석 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Thermal bum of pharynx and larynx can cause dysphagia and dyspnea which can be life threatening. Pain of larynx due to thermal bum does not subside sufficiently to drug therapy, Physiologic therapy. Here a case of acute epiglottitis with severe pain, which was successfully treated with superior laryngeal nerve block, is reported.

PC 기반의 플랫폼간의 상호 연동을 위한 Intelligent Mirroring

임경은,황대준 成均館大學校 科學技術硏究所 1995 論文集 Vol.46 No.1

Creating collaborative environment on heterogeneous PC-based multimedia platforms running on different operationg systems has been of great importance to allow natural interaction among remote users through interoperability. Intelligent Mirroring is incorporated into our Multimedia Distance Learning System for IBM PCs and Apple's Power Macintoshs running Windows (ver. 3.1, ver. 95) and System (ver. 7.1, ver. 7.5), respectively. Upon messages from platforms via Ethernet involved the distance learning situation, Intelligent Mirroring its functions based on system homogeniety: liasion of messages for homogeneous platforms, interpretation of events and conversion of data encoding formats for heterogeneous platforms involved in the interaction. In such a distance learning situation requiring high degree of interaction Intelligent Mirroring contributes not only to establishing function and content sharing at a fine grain level with low cost, but also to minimize traffics related to interpretation of events to be shared by platforms participating in the collaboration.

급성 대상포진 환자에서 고주파 열응고술을 이용한 교감신경절제술의 효과

임경준,위상우 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.2

The Effect of a Sympathectomy Using Radiofrequency Thermocoagulation in Patients with Acute Herpes Zoster - A case report - Kyung Joon Lim. M.D., and Sang Yu Wei. M.D. Department of Anesthesiology, College of Medicine, Chosun University, Gwangju, korea Herpes zoster represents the reactivation of latent varicella-zoster virus located in the dorsal root ganglion. The virus multiplies and migrates to the skin surface producing a characteristic, usually painful, pustular eruption. Severe pain during the acute phase of herpes zoster has been associated with a higher risk of developing postherpetic neuralgia. Sympathetic ganglion blocks have been used for patients in the acute phase of herpes zoster to alleviate pain and prevent postherpetic neuralgia. We experienced 2 cases of patients with acute herpes zoster in which one of them presented with pain localized to the dermatomal distribution of L_2-3, the other T_3. The authors report the results achieved in treatment of the herpes zoster patients, using radiofrequency thermocoagulation of the sympathetic ganglion. (Korean J Anesthesiol 2001; 41: 260~264)

배추 시스테인 단백질 분해 효소 억제 유전자 BCPI-1의 발현과 종자 발아 및 유묘 생장과의 연관성

홍준기,이은영,김정률,양경애,최영주,정우식,김호일,윤대진,이상열,조무제,임체오 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Phytocystatins are protein inhibitors of cysteine proteinases of the papain family that have been identified in both monocot and dicot plants. A cDNA encoding a phytocystatin, BCPI-1 (Brassica Cysteine Proteinase Inhibitor-1) has been isolated from Chinese cabbage (Brassica campestris L. ssp. pekinensis) flower buds. Here, we tested whether BCPI-1 transcription is regulated by hormones, and could be involved in regulating cysteine proteinases during and after germination. BCPI-1 was sensitive to exogenous GA_(3) and ABA, which are important factors controlling seed germination, suggesting that the expression of BCPI-1 is hormonally regulated. We introduced a recombinant plasmid containing the full-length BCPI-1 cDNA under the control of cauliflower mosaic virus 35S promoter into rice embryogenic calli using the particle delivery method, and regenerated a number of transgenic rice plants. Constitutively over-expressed BCPI-1 caused changes in overall plant growth and development, including reduced germination and seedling growth. These data support the role of the BCPI-1 in the regulation of endogenous proteinases during both seed germination and subsequent seedling development. Phylocystatins은 papain계열의 cysteine 단백질 분해 효소 활성을 특이적으로 억제하는 억제자로 다양한 식물 종으로부터 분리되었다. 본고에서는, 배추 화아 cDNA library로부터 분리된 phytocystatin인 BCPI-1(Brassica Cysteine Proteinase Inhibitor-1)의 생체 내 기능에 대해 연구하였다. 먼저, BCPI-1 전사체는 발아 조절에 중요한 영향을 미치는 GA₃와 ABA에 의해 예민하게 증가, 혹은 감소되는 반응을 보임으로써, BCPI-1이 식물 호르몬의 영향을 받으며, 특히 발아나 유묘의 생장 조절에 관련이 있음을 알 수 있었다. Particle bombardment 방법을 통하여 BCPI-1을 벼의 배 형성 세포 내에 도입, 재분화 시켜 형질 전환 벼를 생성하였다. CaMV 35S promoter의 조절에 의해 지속적인 BCPI-1 발현을 보이는 형질 전환 벼의 경우, 발아와 유묘 생장이 현저히 지연되었다. 위의 결과들을 바탕으로, BCPI-1이 식물체 내에서 생성되는 cysteine 계열의 단밸질 분해 효소 활성을 조절하여 종자의 발아와 유묘의 생장에 영향을 미치는 것으로 추측한다.

Stent삽입을 이용한 관동맥성형술로 치료한 내장역위가 동반된 우심증의 급성 심근경색증환자 1예

황경화,김태용,김준영,최유정,최홍엽,오재인,임상욱,차동훈 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.9

Eisenmenger씨 증후군 산모의 긴박 제왕절개술시 전신마취 경험

김준,고우석,정종달,유병식,임경준,소금영,안태훈,한승룡 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Eisenmenger's syndrome describes a situation in which the left-to-right intracardiac shunt is reversed as a result of increased pulmonary vascular resistance. The patients with Eisenmenger's syndrome are poorly tolerated and markedly increased maternal mortality to 30 - 50% during pregnancy, Physiological change of pregnancy decreases systemic vascular resistance that further aggravates the bi-directional or left shunt associated with Eisemnenger's syndrome. We report a case of 37 weeks a pregnant woman with an urgent cesarean section under general anesthesia for preterm labor. She was a pregnant patient with Eisenmenger's syndrome and did not receive antenatal care during pregnancy. Anesthesia was induced with ketamine-midazolam-fentanyl and maintained with ketamine-midazolam. The patient was ventilated with 100% O₂. Blood pressure was maintained with intravenous phenylephrine, crystalloid solution, and blood. Phenylephhne was used to maintain systemic vascular resistance (SVR). Even though the patient was carried rapid and adequate medical management, the patient was transferred to the ICU in an intubated state and died 2 days after surgery. We conclude that the parturients with Eisenmenger's syndrome require more regular, careful antenatal care, monitoring, and adequate management.

양성형 골화석증

김경아,김숙영,고광준 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.1

A 37-year-old male with the complaint of intermittent gingival swelling and dull pain associated with the food impaction of the mandibular third molar area was referred to our department of Chonbuk National University Hospital. The dental history of the patient showed that he had extracted the maxillary left third molar without complications two years ago. Intraoral and panoramic radiographs showed diffuse increased radiopacity of the maxilla and mandible. The trabecular pattern was obliterated. Postero-anterior skull and lateral skull radiographs showed thickening of cortical bone and diffuse increased radiopacity of the skull. Additional radiographs showed similar changes in the lumbar spine, clavicles, iliac bone and femur. However, no evidence of osteomyelitis was observed clinically and radiographically. Laboratory findings showed normal values of serum calcium, phosphorus, and alkaline phosphatase. Based on the radiographic examinations and the laboratory findings, final diagnosis was made as a benign osteopetrosis. (Korean J Oral maxillofc Radiol 2000; 30: 80-86)

WHO 침구임상 지침서 개정을 위한 국제회의 보고

박히준,서정철,김세현,김상우,안경애,임사비나,김용석,최도영,강성길 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

The Working Group on the revision of Clinical Research Methodology for Acupuncture met in Seoul, Republic of Korea from 24 to 26 August 2005. The main objectives of the meeting were to review the regional publication guidelines for Clinical Research on Acupuncture, to make necessary revisions in the guidelines, to make recommendations on further collaboration and activities in the field of research on acupuncture, and to discuss scientific evidence-based approaches in the clinical research on acupuncture. Fourteen members from the eight Member States, one secretariat staff from the WHO Regional Office for the Western Pacific and ten observers from the Republic of Korea attended the meeting. The members presented their papers to review the current status of clinical research on acupuncture. The drafts of proposed revision to the previous guidelines for clinical research methodology on acupuncture were discussed extensively. The issues covered during the discussion included: the definition of the new terms; reorganization of clinical research design; revision and update of contents (e.g., control group); introduction of Institutional Review Board (IRB) on the section of ethical approval; additional outcomes including health-related quality of life (HRQOL), qualitative measures, etc. In the course of these discussions, the working group developed the revised guidelines for clinical research on acupuncture and made recommendations for promoting the dissemination of the revised guidelines.