급성 주정 중독 흰쥐에서 간의 Aryl sulfotransferase and UDP-Glucuronosyltransferase 활성에 미치는 총담관 결찰의 영향

권삼옥,김여희 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.2

The activities of aryl sulfotransferase (AST) isozymes Ⅰ-Ⅱand Ⅲ-Ⅳand UDP-glucuronosyltransferase (UDP-GT) were measured in rats with acute ethanol intoxication after common bile duct(CBD) ligation to investigate the adverse effects of alcohol ingestion to the liver under the hepatobiliary disease. Serum AST Ⅰ-Ⅱ and AST Ⅲ-Ⅳ activities in CBD ligated rats combined with acute ethanol intoxication showed greater increases than that in CBD ligation alone. These results indicate that the leak of hepatic AST isozymes into blood is facilitated in CBD ligated rats combined with acute ethanol intoxication than in CBD ligation alone due to aggravated hepatic membrane damage. Liver mitochondrial AST Ⅰ-Ⅱ and AST Ⅲ-Ⅳ activities in CBD ligated rats combined with acute ethanol intoxication showed less increases than that in CBD ligation alone. However, liver microsomal UDP-GT activity in CBD ligated rats combined with acute ethanol intoxication showed a more decrease than that in CBD ligation alone. On the other hand, when acute ethanol intoxication was combined with CBD ligation, the values of Vmax of the liver mitochondrial AST Ⅰ-Ⅱ, AST Ⅲ-Ⅳ and liver microsomal UDP-GT decreased significantly than that in CBD ligation alone. However, the values of Km of above hepatic enzymes did not change. Viewed from these results, when acute ethanol intoxication was combined with cholestasis, these enzymes in the liver seem to be decreases their biosynthesis than that in cholestasis. According to all of the results, if ethanol intoxication is combined with cholestasis, the hepatic damage is aggravated.

Polyester 신합섬 직물의 농색염색 및 대전방지가공에 관한 연구 (Ⅰ)

김동권,이주형,이난형,김삼수,조환 영남대학교 지역발전연구소 1996 새마을지역개발연구 Vol.18 No.-

The Dyeing processing, which can be a low-cost and easily application to production field was investigated by using some bathochromic agent and dyestuffs. The Δ L values and dye up-takes of threated several fabrics were investigated according to the dye concentration and pH of dyebath. The results were as follows : 1. The selection of bathochromic agent acts as important factor for improvment of bathochromic property of fabrics. 2. The pH of dyebath has a little effect on bathochromic effect. 3. In case of one bath treatment, the bathochromic agent has little effect on the improving bathochromic property of treated fabric. 4. The efficiency order of bathochromic effect is DTY + fila.> CVY > DTY and fabric structure is also effect on the bathochromic property of the polyester fabric.

야간 혈압 변동과 좌심실 질량, 이완기 기능 및 QT 간격과의 관계

김수중,이병호,손일석,강흥선,조정휘,김권삼,송정상,배종화 대한간질학회 2003 대한간질학회지 Vol.9 No.1

진동에 의한 혈관 내 폐 보조장치의 산소전달 특성

김기범,권대규,이삼철,김성종,정인수,오인혁,김기주,변윤섭,정경락 한국화학공학회 2004 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.42 No.2

본 연구는 급성호흡부전환자를 치료하기 위하여 사용되고 있는 혈관 내 폐 보조장치의 기체전달을 향상시키기 위하여 중공사막에 진동기법을 사용하여 기체전달을 향상시키고자 시도하였다. 그리고 혈관 내 폐 보조장치를 정맥에 삽입하기 전, 혈관 내 폐 보조장치의 설계조건을 실험적 모델을 통하여 기체전달을 예측할 수 있는 예측식을 만들고자 하였다. 실험결과, 본 연구에서는 진동기법이 기체전달을 향상시키는데 효과적임을 확인할 수 있었다. 뿐만 아니라, 충진율과 가징 주파수의 함수관계를 이용하여 기체전달을 예측 할 수 있었다. 실험에 의하여 얻어진 결과는 예측식에 의하여 얻어진 결과와 유사한 결과를 얻었다. 그러므로 본 연구에서는 충진율과 가진 주파수의 함수를 이용하여 VIVLAD의 기체전달을 예측할 수 있었다. In this paper, we tried to improve gas exchange of the vibrating intravascular lung assist device(VIVLAD) using vibrating method in the hollow fiber membrane, for the patients suffering from acute respiratory distress syndrome(ARDS). And we tried to formularize prediction equations to make a prediction about gas transfer for designing intravenous artificial lung assist device, and designed modules under various conditions were studied through an experimental modeling before inserted the artificial lung assist device into as venous. As a result, we are convinced that vibration method is very useful for the has transfer increasing. Also, we can estimate the gas transfer as a function of the packing density and excited frequencies. The gas transfer obtained from the experiment was similar to that from the prediction equation, confirming the usefulness prediction equation. Therefore, we can estimate the gas transfer of the VIVLAD as a function of the packing density and excited frequencies.

일부 자동차 공장 근로자들의 職業的 特性과 社會 心理的 Stress의 相關性 硏究

김성삼,홍지우,한현정,최희석,권소희,정해경,김삼태,송용선,이기남 한국전통의학연구소 2004 한국전통의학지 Vol.14 No.1

〈Objective〉 This study were carried out to study to assess the relationship between job characteristics, general characteristics, health behaviors, and psychosocial distress and suggested the preventive oriental medicine approaches in occupational health area. 〈Methods〉 We measured job characteristics(job demand, job control, jop insecurity) by The Karasek's Job Content Questionnaire, health behaviors(smoking, drinking, exercise, coffee), general characteristics at work by a self-administered questionnaire. Psycho social distress was measured by PWI(Psychosocial Well-being Index), a 18-item self- administered instrument. 370 data for research were collected through the process of oriental health examination with questionnaire in workplace. Statistical analysis was done by t test, oneway ANOVA, and hierarchical multiple regression analysis with SPSSWIN (version 10.0) 〈Results〉 Among the 152 respondents, the prevalence of high job strain was 27%(41 persons). The Odds ratio of high job strain was 3.11(95 2.12~4.11), and those of passive group and active group were 2.01(95 0.83~2.76) and 1.80(95 0.83~2.76), respectively. Our results supported the association between psychosocial distress and job strain. 〈Conclusion〉 The odds ratio of high strain isolated group(high strain group+low social support) was 3.59(95 2.05 5.13), but the odds ratio of high strain collective group was 1.32(95 0.23 2.41). Social support at work was modifing factor of the association between psycho social distress and job strain. Therefore we reviewed the evidence that economic depression was associated with psycho social distress in this study, and that the strength of the social support was important in maintain health.

柔道試合에서의 體級別 使用 技術 頻度에 關한 比較硏究

崔鍾三,金官鉉 龍仁大學校 1990 용인대학교 논문집 Vol.6 No.-

The frequency of technical application by weight class towards 370 athletes participated in the 1st Selection Match of the National Representatiues in 1989, Concurrenthy the 28th National Judo Championships by weght class, the frequency of technical application by weight class towards 265 athletes participated in the 1st Selection Match of the National Representation in 1990 and the National judo Champion for the 27th Presidential cup are studiet and avalyzed. The Hand Technique was mush used in the light weight, while the foot technique was mairly applied in the heawy weight auording to the presious srudy. As noted above this diferent from the previous research, both the Hand and Foot Technique were applied in the heavey and light weight in all the compplied in the heavey and light weight in all the competitions of 1989 and 1990. In the case of the application of the Foot Technique showed constauihy a high propation in all heavy weights, while in the heavy weight was much depended on GATAME in the defeat. 1) Extra Light Class Prior to the 1989s athletic match, it was applied in sequence of the Hand Technique (SEOI-NAGE), the Foot Technique (UCHI-MATA) and CATAME (KAMI-SHIHO-GATAME). As the result, it was turned out in the sequence of the Hand Technique, the Foot Technique, an GATAME (UDE-HISHIGI-JUJI-GATAME). 2) Half Light Class In the athletic match of 1989, the sequence was turned out to be the Foot Technique (KO-UCHI-GARI), the Hand Technique (SEOI-NAGE) and GATAME (HON-KESA-GATAME). According to the Athletic Comptition in 1990, the order was stood in sequence of the Foot Technique (O-SOTO-GARI), the Hand Technique (SEOI-NAGE) and GATAME (KAMI-SHIHO-GATAME). 3) Light Class While it showed an order of the Foot Technique (KO-UCHI-GARI), the Hand Technique (SEOI-NAGE) and GATAME in the Athletic mach in 1989. Also the Foot Technique, the Hand Technique and Nurugi were shown as its sequence in 1990. 4) Half Middle Class The sequence stood in order of the Foot Technique and the Hand Technique in terms of the Athlitic match of 1989 Also in the Athetic match was in sequence of the Foot Technique and the Hand Technique. 5) Middle Class The athletic competition has indicated its order as the Foot Technique the Hand Technique and NURUGI in 1989. Also in terms of its order the athletic meeting was the Foot Technique, the Hand Technique in 1990. 6) Half Heavy Class The sequence of the Foot Technique, the Hand Technique and the Waist Technique was applied the athletic competition in 1989. The athlitic completion in sequence was in order of the Foot Technique, the Hand Technique and the Waist Technique in 1990 7) Heavy Class It was used in the sequence of the Foot Technique, NURUGI(KOYT-NURUGI) and the Hand Technique (HOBOKTARI-KOLKI) in the athletic competition in 1990. Meanwhile, the sequence of on application in the 1990. athletic competition was in order of the Foot Technique (HOBOKTARI-KOLKI), the Hand Technique (BIT-DANGKY-O-CHIKI) and NURUGI (KYOT-NURUGI). Recommendations for Further Research There are several directions in which future research in this area could be pursued. Several proposals are conduction for on improvement of our internal Judo. 1) The contest in most cosets was determened either by the hand or the Foot Technique both in 1989 and 1990. Therefore, a variety of techniques are necessarily required to learn other than these techniques in the future. In addition, KUD-CHIKI will be able to exercise a great influence for ocitory. Further, the technique of KUD -CHIKI has to he more often applied. 2) Such technique as may be applied by other athletes shall be researched and improved, also individual player has to do its best in the development of the Korean Style Judo Technique is quite similor to KAWI -CHIKI. 3) A numver of investigators recommended in the foreyuing study, but the Judo player will be able to play more intensive style talon aim at the gaining of points. 4) It is even more desirous that the Judo players of may country have to concentrate extorts in the physical training in order to cope with the changing situation of the international Judo from the technical Judo to the Judo of strength. 5) Currently, the Juo Uniform had a narrow to take hold of during the contests, but the international Judo Federation has taken necessary measures to broaden the uniform's width in order to the athletes, therefore it is helieved argenthy necessary that Judo players are able to egage in the whole hearted devotion to an assault hased on the technique than to a struggle to take hold of its oppaonent.

급성 심근경색증을 동반한 혈전성 혈소판 감소성 자반증 1예

이태희,김진혁,김완중,박지영,강흥선,조정휘,김권삼,송정상,배종화 대한순환기학회 2003 Korean Circulation Journal Vol.33 No.11

急性骨髓性 白血症에서의 試驗管內 集落細胞 形成에 관한 연구

고석만,조덕연,박철신,강원권,김민범,김삼용,노흥규 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1 No.1

To evaluate the in vitro granulocyte-macrophage colony formation in acute myeloblastic leukemia and the prognostic implications of these results, the author performed the in vitro agar culture of bone marrow cells in 10 patients with acute myeloblastic leukemia (AML) and 5 control subjects. Culture medium was composed of 20% fetal calf serum(FCS), 50% Iscove's medium, 0.3% agar, 10% colony stimulation factor (CSF), and 2×105 cells/ml. Human placental conditioned medium (HPCM) and phytohemagglutinin-leukocyte conditioned medium (PHA-LCM) were used as colony stimulating factor. Colony counting was done on 7th day of culture. Colony was defined as containg 20 or more cells, and cluster was defined as containing 3 - 19 cells. The results were as followings, 1. In control subjects, the number of clusters formed was 3-47/2×10^(5) cells (20±19)and that of colonies was 5-24/2×10^(5) cells (14±9) when stimulated with HPCM. When stimulated with PHA-LCM, the number of clusters formed 5-39/2×10^(5) cells(18±16) and that of colonies was 6-13/2×10^(5) cells (9±3). 2. In AML patients, 3 groups were recognized according to pattern of colony formation : 1) non-forming 2) cluster forming 3) both cluster and colony forming. Of 10 cases, 5 cases were 'non-forming', 2 cases were 'cluster forming'; and 3cases wer cluster and 'colony forming'; 3. All 5 cases 'non-forming' cases, one of 2 cases of 'cluster forming'; and none of 3 cases of 'cluster and colony forming' achieved complete remission. So, there was significant difference in remission rate in the different growth types. These results suggest that granulopoiesis in AML patients is impaired and the pattern of in vitro CFU-L(colony forming unit-leukemia) formation has prognostic significance.

急性骨髓性 白血病에서의 試驗管內 集落細胞 形成에 관한 연구

고석만,조덕연,박철산,강원권,김민범,김삼용,노홍규 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1991 No.-

急性骨髓性 白血病에서의 試驗管內 集落細胞 形成에 관한 연구

고석만,조덕연,박철신,강원권,김민범,김삼용,노흥규 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

To evaluate the in vitro granulocyte-macrophage colony formation in acute myfloblastic leukemia and the prognostic implications of these results, the author performed the in vitro agar culture of bone marrow cells in 10 patients with acute myeloblastic leukemia (AML) and 5 control subjects. Culture medium was composed of 20% fetal calf serum(FCS), 50% Iscove's medium, 0.3% agar, 10% colony stimulation factor (CSF), and 2 × 10 exp (5) cells/ml. Human placental conditioned medium (HPCM) and phytohemagglutinin-leukocyte conditioned medium (PHA-LCM) were used as colony stimulating factor. Colony counting was done on 7th day of culture. Colony was defi ned as containg 20 or more cells, and cluster was defined as containing 3-19 cells. The results were as followings, 1. In control subjects, the number of clusters formed was 3-47/2 × 10 exp (5) cells (20±19)and that of colonies was 5-24/2 × 10 exp (5) cells (14±9) when stimulated with HPCM. When stimulated with PHA-LCM, the number of clusters formed 5-39/2 × 10 exp (5) cells(18±16) and that of colonies was 6-13/2 × 10 exp (5) cells (9±3). 2. In AML patients, 3 groups were recognized according to pattern of colony formation: 1) non-forming 2) cluster forming 3) both cluster and colony forming. Of 10 cases, 5 cases Were `non-forming', 2 cases were `cluster forming'; and 3cases wer cluster and `colony forming'; 3. All 5 cases 'non-forming' cases, one of 2 cases of `cluster forming'; and none of 3 cases of `cluster and colony forming' achieved complete remission. So, there was significa nt difference in remission rate in the different growth types. These results suggest that granulopoiesis in AML patients is impaired and the pattern of in vitro CFU-L(colony forming unit-leukemia) formation has prognostic significance.