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RISS 인기검색어
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- 저자 : ( Joong Haeng Choh ) (검색결과 3 건)
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Subclinical Hypothyroidism and Coronary Revascularization After Coronary Artery Bypass Grafting
Kong, Sung Hye,Yoon, Ji Won,Kim, Sang Yoon,Oh, Tae Jung,Park, Kay-Hyun,Choh, Joong Haeng,Park, Young Joo,Lim, Cheong Elsevier 2018 The American journal of cardiology Vol.122 No.11
<P>We aimed to investigate long-term cardiovascular sequelae after coronary artery bypass grafting (CABG) in patients with subclinical hypothyroidism (SCH). All-cause and cardiovascular-related mortality, and cardiovascular events were retrospectively reviewed in 222 euthyroid and 36 SCH patients who underwent CABG. During a mean follow-up period of 8.2 ± 4.1 years, there were 90 incidents of all-cause deaths, 20 cardiovascular-related deaths, 70 major cardiovascular adverse events, 6 myocardial infarctions, 12 unstable anginas, 31 strokes, 23 hospitalizations due to heart failure, 15 atrial fibrillation (AF) events, and 27 coronary revascularizations. The incidence rate of coronary revascularization was significantly higher in patients with SCH (n = 6, 16.6%) than in euthyroid patients (n = 20, 9.0%), with a hazard ratio (HR) of 3.179 (95% confidence interval [CI] 1.174, 8.605; <I>p</I> = 0.023) after adjustment. In subgroup analysis, SCH patients who experienced postoperative AF within 3 months after CABG surgery had a significantly higher risk of coronary revascularization (n = 4, 25.0%) than euthyroid patients without AF (n = 14, 8.9%) after adjustment (HR 11.759, 95% CI 2.747, 50.343, <I>p</I> = 0.001). The frequency of fatal or nonfatal unstable angina was also higher in patients with SCH (n = 2, 12.5%) than in euthyroid patients (n = 4, 2.5%) (HR 16.999, 95% CI 2.242, 128.860, <I>p </I>= 0.006). In conclusion, preoperative SCH is associated with less favorable cardiovascular outcomes, especially coronary revascularization after CABG. Moreover, SCH patients who develop postoperative AF exhibit significantly increased risks of unstable angina and coronary revascularization. Preoperative evaluation of thyroid function may be helpful for predicting long-term outcomes after CABG.</P>
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( Hyuk Yoon ),( Suk-kyun Yang ),( Hoonsub So ),( Ko Eun Lee ),( Sang Hyoung Park ),( Sung-ae Jung ),( Joong Haeng Choh ),( Cheol Min Shin ),( Young Soo Park ),( Nayoung Kim ),( Dong Ho Lee ) 대한내과학회 2019 The Korean Journal of Internal Medicine Vol.34 No.1
Background/Aims: The Crohn’s and Colitis Knowledge (CCKNOW) score does not reflect updated knowledge relating to inflammatory bowel disease (IBD). The aim of this study was to develop, validate, and apply a novel tool to measure dis ease-related knowledge in IBD patients. Methods: A questionnaire composed of 24 items regarding knowledge of IBD was developed: Inflammatory Bowel Disease Knowledge (IBD-KNOW). Discriminate ability of IBD-KNOW was validated in three occupational groups (14 doctors, 20 nurses, and 19 clerks). The CCKNOW and IBD-KNOW were administered to IBD patients. Factors affecting the level of IBD-related knowledge were analyzed. Results: The median Inflammatory Bowel Disease Knowledge (IBD-KNOW) score was significantly different among the three groups for validation (22 doctors, 20 nurses, and five clerks; p < 0.001). The IBD-KNOW showed excellent internal con sistency (Cronbach α = 0.952) and high correlation with CCKNOW (Spearman ρ = 0.827, p = 0.01). A total of 200 IBD patients (120 Crohn’s disease, 80 ulcerative coli tis) completed questionnaires. Multivariate analysis showed that a higher IBD-KNOW score than the median was associated with hospitalization history (odds ratio [OR], 2.625; p = 0.003), high education level (OR, 2.498; p = 0.012), and infor mation acquired from patient organization (OR, 3.305, p = 0.035). Conclusions: The IBD-KNOW demonstrated excellent test characteristics. Hospi talization history, education level, and information acquired from patient organi zation play an important role in correct IBD-related knowledge.
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심근경색을 가진 환자에서 호흡정지 T2강조 자기공명영상의 유용성: 지연 조영증강 영상과의 비교
최상일,강성권,유원희,임청,조중행,이활,정진욱,박재형,이경원,Choi Sang Il,Kang Sung-Kwon,Ryu Won Hee,Lim Cheong,Choh Joong Haeng,Lee Whal,Jeong Jin-Wook,Park Jae-Hyung,Lee Kyung Won 대한자기공명의과학회 2003 Investigative Magnetic Resonance Imaging Vol.7 No.2
목적 : 심근경색을 가진 환자에서 호흡정지 T2강조 자기공명영상의 유용성을 알아보고자 하였다. 대상 및 방법 : 심근 생존능을 평가하기 위하여 자기공명영상이 시행된 환자에서 지연 조영증강을 보였던 11명의 환자를 대상으로 하였다. 지연 조영증강을 보이는 심근부위와 비교하여 T2강 조영상에서 일치하는 부위를 고신호강도, 동등신호강도, 저신호강도로 나누어 분석하였으며, 정상 심근과 경색 부위의 신호강도 세기 및 통벽성 범위(transmural extent)을 측정하였다. 환자의 임상정보를 토대로 심근경색의 시기와 T2 강조영상과의 상관관계를 분석하였다. 결과 : T2강조영상에서 5명의 환자의 12분절에서 정상심근에 비하여 경색부위에 고신호강도를 보였으며, 6명의 환자의 12분절에서 저신호강도를 보였다. 경색부위의 고신호강도는 정상심근에 비하여 $175{\pm}9\%$ 이었으며, 저신호강도는 $73{\pm}5\%$ 이었다 (p < 0.05). 통벽성 범위(transmural extent)의 평가에 있어, T2강조영상에서 고신호강도 부위는 지연 조영증강을 보인 부위보다 컸으나 $(100\%\;vs.\;49{\pm}17\%)$, 저신호강도 부위는 일치하였다. T2 강조영상에서 고신호강도는 심근경색후 11일 이내에 보였고, 저신호강도는 7개월 이후에 보였다. 결론 : 호흡정지 T2 강조영상은 부종 및 섬유화 반흔 범위의 평가와 함께 심근경색의 시기를 예측하는 데에 있어 유용할 것으로 사료된다. Purpose : To evaluate the usefulness of breath-hold T2-weighted MR imaging in patients with myocardial infarction. Materials and Methods : We investigated 11 patients with myocardial infarction who shown delayed enhancement on MR imaging. Infarcted myocardium on T2-weighted MR imaging was classified as high, iso, and low signal area comparing with normal myocardium. The intensity and transmural extent of infracted myocardium was also analyzed. On the basis of clinical information, the stage of infracted myocardium on T2-weighted MR imaging was assessed. Results : It was observed high signal area in 12 segments of 5 patients, low in 12 segments of 6 patients on T2-weighted MR imaging. The high signal intensity of infarcted myocardium was shown as $175{\pm}9\%$ comparing with that of the normal myocardium, low signal intensity as $73{\pm}5\%\;(p\;<\;0.05)$. In the evaluation of transmural extent, the high signal areas on T2-weighted MR imaging were larger than infarct area on delayed enhancement imaging $(100\%\;vs.49\%{\pm}17\%)$, whereas low signal areas on T2-weighted MR imaging correlated. High signal area was visualized on T2-weighted MR imaging within 11 days, whereas low-signal area was seen after 7 months. Conclusion : Breath-hold T2-weighted MR imaging is useful in the evaluation of stage as well as edema and fibrous scar in patients with myocardial infarction.
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