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Hung-Cuong Trinh,Van-Huy Pham,Anh H. Vo 한국인터넷정보학회 2023 KSII Transactions on Internet and Information Syst Vol.17 No.12
Ensuring reliability of a machinery system involve the prediction of remaining useful life (RUL). In most RUL prediction approaches, noise is always considered for removal. Nevertheless, noise could be properly utilized to enhance the prediction capabilities. In this paper, we proposed a novel RUL prediction approach based on noise injection and a Kalman filter ensemble of modified bagging predictors. Firstly, we proposed a new method to insert Gaussian noises into both observation and feature spaces of an original training dataset, named GN-DAFC. Secondly, we developed a modified bagging method based on Kalman filter averaging, named KBAG. Then, we developed a new ensemble method which is a Kalman filter ensemble of KBAGs, named DKBAG. Finally, we proposed a novel RUL prediction approach GN-DAFC-DKBAG in which the optimal noise-injected training dataset was determined by a GN-DAFC-based searching strategy and then inputted to a DKBAG model. Our approach is validated on the NASA C-MAPSS dataset of aero-engines. Experimental results show that our approach achieves significantly better performance than a traditional Kalman filter ensemble of single learning models (KESLM) and the original DKBAG approaches. We also found that the optimal noise-injected data could improve the prediction performance of both KESLM and DKBAG. We further compare our approach with two advanced ensemble approaches, and the results indicate that the former also has better performance than the latters. Thus, our approach of combining optimal noise injection and DKBAG provides an effective solution for RUL estimation of machinery systems.
( William Sievert ),( Huy Trinh ),( Giampiero Carosi ),( Ulus Akarca ),( Adrian Gadano ),( Francois Habersetzer ),( David Wong ),( Meghan Lovegren ),( Hui Zhang ),( Cyril Llamoso ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: The aim of this study was to elucidate the antiviral efficacy and safety of telbivudine in Korean treatment-naive chronic hepatitis B (CHB) patients. Methods: A total of 143 treatment-naive patients who had been treated with telbivudine for at least 6 months were consecutively enrolled. We determined the cumulative rates of virologic response (<12 IU/ml by PCR assay), serologic response, biochemical response and monitored any side effects. Results: The median age and follow-up duration were 50.7 years and 16.4 (range 6-24 months) months, respectively. Sixty seven patients (46.9%) were positive for HBeAg and the median serum HBV DNA level was 7.23 (range 4.31-8.26) log IU/ml. In HBeAg positive group, the cumulative probabilities of HBV DNA undetectability were 14.9% , 24.6%, 34.4% and 26.3% at 6, 12, 18 and 24 months, respectively. Partial virologic response at 6 months occurred in 82.1% of patients and inadequate virologic response at 6 months in 3.0%. During the follow-up period, 8 patients achieved HBeAg loss and 3 patients achieved HBeAg seroconversion. Meanwhile, in HBeAg-negative group, the cumulative rates of virologic response were 64.5%, 86.4%, 82.1% and 81.3%, respectively and the cumulative rates of biochemical response were 89.5%, 98.3%, 100% and 100%, respectively. Among the all patients, there were 42 cases of virologic breakthrough and 21 cases of genotypic resistance and virologic breakthrough. There were 46 (32.2%) cases of CK elevation and 2 (1.4%) cases of myopathy. However, there was no clinically significant safety issue. Conclusions: In Korean treatment-naive HBeAg-negative CHB patients, telbivudine therapy induced favorable virologic, serologic and biochemical responses.
Lan, Truong Thi Phuong,Huy, Nguyen Duc,Luong, Nguyen Ngoc,Quang, Hoang Tan,Tan, Trinh Huu,Thu, Le Thi Anh,Huy, Nguyen Xuan,Loc, Nguyen Hoang The Korean Society of Plant Biotechnology 2019 식물생명공학회지 Vol.46 No.3
The aim of this study is to evaluate the effect of yeast extract (YE) and salicylic acid (SA) on the expression of curcuminoid-biosynthesis genes (CzDCS and CURS1-3), and accumulation of curcumin in Curcuma zedoaria cell cultures. The results showed that, in cells treated with YE or SA, the expression levels of curcuminoid genes were 1.14- to 3.64-fold higher than the control (untreated cells), in which the YE exhibited a stronger effect in comparison with SA. Curcumin accumulation also tended to be similar to gene expression, curcumin contents in YE- or SA-treated cells were 1.61- to 2.53-fold higher than the control. The SA treatment at the fifth day of culture stimulated the curcumin accumulation and expression in all four genes compared to that at the beginning. While the YE treatments gave different results, the CzCURS1 and CzCURS3 genes were expressed strongly in cells that were treated at the beginning. However, the CzDCS and CzCURS2 genes showed the opposite expression pattern, they were activated strongly in the treatments at day five of the culture. However, the content of curcumin reached its maximum value on the fifth day of culture in all investigations.
Nguyen, Cam Phu Thi,Trinh, Thanh Thuy,Dao, Vinh Ai,Raja, Jayapal,Jang, Kyungsoo,Le, Tuan Anh Huy,Iftiquar, S M,Yi, Junsin Institute of Physics 2013 Semiconductor science and technology Vol.28 No.10
<P>Indium tin zinc oxide (ITZO)-based thin-film transistors (TFTs) were fabricated by dc magnetron sputtering in Ar + O<SUB>2</SUB> reactive gas, at room temperature. We present the effect of post-deposition annealing of ITZO thin films on the oxygen vacancies and on the characteristics of TFT devices. When the annealing temperature was increased from room temperature to 350 °C, the resistivity of ITZO film increased from 2.05 × 10<SUP>1</SUP> to 2.60 × 10<SUP>3</SUP> Ω cm and the interface trap density (<I>N</I><SUB>t</SUB>) of the TFTs reduced from 3.18 × 10<SUP>13</SUP> to 4.83 × 10<SUP>11</SUP> cm<SUP>−2</SUP>. The TFT with the ITZO film which was annealed at 350 °C showed a very small shift in turn-on voltage, even after applying positive bias stress of +12 V for 10<SUP>4</SUP> s. The current–voltage characteristics of 350 °C annealing temperature sample indicated that these TFTs were in an enhanced mode of transistor operation with a high on-to-off current ratio of ∼1.26 × 10<SUP>6</SUP>, high field-effect mobility of 14.17 cm<SUP>2</SUP> V<SUP>−1</SUP> s<SUP>−1</SUP>, and low subthreshold slope of 1.23 V/dec. The trapping time reduced from 3720 to 1546 s as the annealing temperature increased from room temperature to 350 °C. These results suggest that thermal annealing played an important role in reducing defects as well as improvement in stability of the TFTs.</P>
Nguyen Van Quy,Tran Minh Hung,Trinh Quang Thong,Le Anh Tuan,Tran Quang Huy,Nguyen Duc Hoa 한국물리학회 2013 Current Applied Physics Vol.13 No.8
The controlled synthesis of mesoporous silica and metal oxide nanocomposites with a highly ordered porous structure and large specific surface area for specific applications has been an attractive topic in the field of porous materials. Herein, we introduce a novel method for the fabrication of highly ordered mesoporous structured and large specific surface area Fe2O3/SiO2 nanocomposites, and consider their application in room temperature gas sensors. The mesoporous Fe2O3/SiO2 nanocomposites were synthesised by a two-step method, which combines the hydrothermal growth of Fe2O3 nanoparticles and the microemulsion phase of Brij 56 (C16EO10) surfactant as templates in instantly direct-templating synthesis. This synthesis method enables the fabrication of mesoporous Fe2O3/SiO2 nanocomposites without distortion of the ordered porous structure after calcination at high temperature. The synthesised materials were found to be efficient in a room temperature VOC sensor application, with good recovery.
Nguyen Thi Minh Hong,Nguyen Ba Doan,Nguyen Huy Tiep,Le Viet Cuong,Bui Nguyen Quoc Trinh,Pham Duc Thang,김동현 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
In this work, we study the magnetic properties of a CoFe/NiFe/PZT heterostructured nanocompositethat is affected by the strain in the PZT substrate when a voltage in the range from –250to 250 V is applied. An interesting electric-voltage-controlled magnetic anisotropy, with a relativeincrease in magnetization up to above 100%, is observed. This brings a new challenge to operate alow-power-consuming spin electronic device. We also utilize a theoretical model based on interfacecharge-mediated and strain-mediated magnetic-electric coupling to understand the change in themagnetic properties of the investigated material.
Truong Giang Nguyen,Thanh Khiem Nguyen,Ham Hoi Nguyen,Hong Son Trinh,Tuan Hiep Luong,Minh Trong Nguyen,Van Duy Le,Hai Dang Do,Kieu Hung Nguyen,Van Minh Do,Quang Huy Tran,Cuong Thinh Nguyen 한국간담췌외과학회 2024 Annals of hepato-biliary-pancreatic surgery Vol.28 No.1
Backgrounds/Aims: Parenchymal-sparing anatomical hepatectomy (Ps–AH) based on portal ramification of the right anterior section (RAS) is a new technique to avoid unnecessarily transecting too much liver parenchyma, especially in cases of major anatomical hepatectomy. Methods: We prospectively assessed 26 patients with primary hepatic malignancies having undergone major Ps–AH based on portal ramification of the RAS from August 2018 to August 2022 (48 months). The perioperative indications, clinical data, intra-operative index, pathological postoperative specimens, postoperative complications, and follow-up results were retrospectively evaluated. Results: Among the 26 patients analyzed, there was just one case that had intrahepatic cholangiocarcinoma The preoperative level of α– Fetoprotein was 25.2 ng/mL. All cases (100%) had Child–Pugh A liver function preoperatively. The ventral/dorsal RAS was preserved in 19 and 7 patients, respectively. The mean surgical margin was 6.2 mm. The mean surgical time was 228.5 minutes, while the mean blood loss was 255 mL. In pathology, 5 cases (19.2%) had microvascular invasion, and in the group of HCC patients, 92% of all cases had moderate or poor tumor differentiation. Six cases (23.1%) of postoperative complications were graded over III according to the Clavien–Dindo system, including in three patients resistant ascites or intra-abdominal abscess that required intervention. Conclusions: Parenchymal-sparing anatomical hepatectomy based on portal ramification of the RAS to achieve R0-resection was safe and effective, with favorable short-term outcomes. This technique can be used widely in clinical practice.