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( Thanh Hoa Le ),( Tran Binh Le ),( Thanh Huong Thi Doan ),( Dong Van Quyen ),( Kim Xuyen Thi Le ),( Viet Cuong Pham ),( Mitsuru Nagataki ),( Haruka Nomura ),( Yasunori Ikeue ),( Yoshiya Watanabe ),( 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.4
Avian influenza virus vaccines produced in oil-emulsified inactivated form with antigen content of at least 160 hemagglutinin units (HAU) induced immunity in birds. However, in addition to enhancing the effect of the adjuvant(s), other additional supplemented biological compounds included in inactivated vaccines could produce higher levels of antibody. We examined in chickens, Vietnamese ducks, and muscovy ducks the adjuvant effect of Sophy β-glucan (SBG), a β-1,3-1,6 glucan produced by the black yeast Aureobasidium pollulans strain AF0-202, when administered with an avian influenza H5 subtype vaccine. In Experiment 1, 40 chickens (ISA Brown hybrid), allocated to four groups of ten each, were immunized with Oil-H5N1(VN), Oil-H5N1(CN), Oil-H5N2(CN), and saline (control group), respectively. In Experiment 2, chickens (ISA Brown hybrid), muscovy ducks (French hybrid), and Vietnamese ducks (indigenous Vietnamese) were used to further assess the effect of SBG on immunogenicity of the Oil-H5N1(VN) Vietnamese vaccine. ELISA and hemagglutination inhibition (HI) assays were used to assess the antibody response. The H5 subtype vaccines initiated significantly higher immune responses in the animals dosed with SBG, with 1.0-1.5 log2 higher HI titers and 10-20% ELISA seroconversion, compared with those not dosed with β-glucan. Notably, some of the animals dosed with SBG induced HI titers higher than 9.0 log2 following boosting immunization. Taken together, our serial studies indicated that SBG is a potential effector, such as enhancing the immune response to the H5 vaccines tested.
An adaptive approach for the chloride diffusivity of cement-based materials
Bao-Viet Tran,Duc-Chinh Pham,Mai-Dinh Loc,Minh-Cuong Le 사단법인 한국계산역학회 2019 Computers and Concrete, An International Journal Vol.23 No.2
Adaptive schemes are constructed in this paper for modeling the effective chloride diffusion coefficient of cementbased materials (paste and concrete). Based on the polarization approximations for the effective conductivity of isotropic multicomponent materials, we develop some fitting procedures to include more information about the materials, to improve the accuracy of the scheme. The variable reference parameter of the approximation involves a few free scalars, which are determined through the available numerical or experimental values of the macroscopic chloride diffusion coefficient of cement paste or concrete at some volume proportions of the component materials. The various factors that affect the chloride diffusivity of cement-based material (porous material structure, uncertainty of value of the chloride diffusion coefficient in water-saturated pore spaces, etc.) may be accounted to make the predictions more accurate. Illustrations of applications are provided in a number of examples to show the usefulness of the approach.
Duc Khanh Le,Quang Khai Le,Thi Thuy Hang Tran,Duc Viet Nguyen,Thi Hang Dao,Thi Thuy Nguyen,Xuan Lam Truong,Quang Cuong Nguyen,Huy Phong Pham,Thi Thu Thuy Phan,Gajendra Babu Baktavachalam 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.2
Susceptibility of Asian corn borer (ACB), Ostrinia furnacalis (Guenée) to Bacillus thuringiensis (Bt) Cry1Ab protein was studied between 2015 and 2016 with 11 ACB populations, collected from various geographical regions in Vietnam. A concentration range of Cry1Ab from 0.20 to 26.10 ng/cm 2 of diet was evaluated against F 1 ACB neonates using diet surface-overlay bioassays. Mortality data was recorded daily until seven days after infestation. Growth inhibition was recorded at the end of seven days. The median lethal concentration (LC 50 ) varied ≈3-fold among the different populations, ranging from 0.58 to 1.83 ng/cm 2 of diet with an overall mean of 0.86 ng/cm 2 of diet. Even the lowest concentration of 0.20 ng/cm 2 caused 73.53% growth inhibition. > 90% growth inhibition was achieved at 0.82 ng/cm 2 or higher concentrations. The results reflect natural variation in Bt susceptibility among ACB populations rather than variation caused by prior exposure to selection pressures. LC 99 value (17.26 ng/cm 2 ) was generated by pooling mortality data across different populations. The upper fiducial limit of LC 99 (24.38 ng/cm 2 ) could be a potential diagnostic dose for future resistance monitoring programs. The findings from this study suggest that ACB populations in Vietnam are highly susceptible to Cry1Ab protein. This is the first report of Cry1Ab susceptibility of different ACB populations in Vietnam and will serve as a baseline for future resistance monitoring work.
New Alkaloids and Anti-inflammatory Constituents from the Leaves of Antidesma ghaesembilla
Van Kiem, Phan,Cuong, Le Canh Viet,Trang, Do Thi,Nhiem, Nguyen Xuan,Le Tuan Anh, Hoang,Tai, Bui Huu,Huong, Le Mai,Van Minh, Chau,Lee, Taek Hwan,Kim, Sun Yeou NATURAL PRODUCT COMMUNICATIONS 2017 Natural product communications Vol.12 No.1
Optimization of Spin-Valve Structure NiFe/Cu/NiFe/IrMn for Planar Hall Effect Based Biochips
Bui Dinh Tu,Le Viet Cuong,Tran Quang Hung,Do Thi Huong Giang,Tran Mau Danh,Nguyen Huu Duc,CheolGi Kim IEEE 2009 IEEE transactions on magnetics Vol.45 No.6
<P>This paper deals with the planar Hall effect (PHE) of Ta(5)/NiFe(t<SUB>F</SUB>)/Cu(1.2)/NiFe(t<SUB>P</SUB>)/IrMn(15)/Ta(5) (nm) spin-valve structures. Experimental investigations are performed for 50 mumtimes50 mum junctions with various thicknesses of free layer (t<SUB>F</SUB> = 4, 8, 10, 12, 16, 26 nm) and pinned layer (t<SUB>P</SUB> = 1, 2, 6, 8, 9, 12 nm). The results show that the thicker free layers, the higher PHE signal is observed. In addition, the thicker pinned layers lower PHE signal. The highest PHE sensitivity S of 196 muV/(kA/m) is obtained in the spin-valve configuration with t<SUB>F</SUB> = 26 nm and t<SUB>P</SUB> = 1 nm. The results are discussed in terms of the spin twist as well as to the coherent rotation of the magnetization in the individual ferromagnetic layers. This optimization is rather promising for the spintronic biochip developments.</P>
Characterization of Ag-Doped p-Type SnO Thin Films Prepared by DC Magnetron Sputtering
Pham, Hoai Phuong,Thuy, Thanh Giang Le,Tran, Quang Trung,Nguyen, Hoang Hung,My Hoa, Huynh Tran,Thi Thu, Hoang,Cuong, Tran Viet Hindawi Limited 2017 Journal of nanomaterials Vol.2017 No.-
<P>Crystalline structure and optoelectrical properties of silver-doped tin monoxide thin films with different dopant concentrations prepared by DC magnetron sputtering are investigated. The X-ray diffraction patterns reveal that the tetragonal SnO phase exhibits preferred orientations along (101) and (110) planes. Our results indicate that replacing Sn<SUP>2+</SUP> in the SnO lattice with Ag<SUP>+</SUP> ions produces smaller-sized crystallites, which may lead to enhanced carrier scattering at grain boundaries. This causes a deterioration in the carrier mobility, even though the carrier concentration improves by two orders of magnitude due to doping. In addition, the Ag-doped SnO thin films show a p-type semiconductor behavior, with a direct optical gap and decreasing transmittance with increasing Ag dopant concentration.</P>