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( Geun-whi Park ),( Tae-wook Kim ),( Sung-min Park ),( Hyun-joo Lee ),( Hyun Ju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon- 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Eruptive pseudoangiomatosis (EPA) is acute, self-limiting dermatosis characterized by the sudden onset of bright red angioma-like papules often surrounded by pale halo. The pathogenesis of EPA is still unknown, but insect bites, especially mosquito have been proposed as a potential causative factor of the disease. Objectives: To clarify the relationship between mosquito bites and EPA after analyzing seasonal variation in the incidence of EPA. Methods: We retrospectively analyzed the clinical data of 55 patients with EPA at Pusan National University Hospitals (Busan and Yangsan) from 2005 to 2016. Results: Forty-eight (87.2%) of 55 patients were diagnosed as EPA in autumn (25/55, 45.4%), and summer (23/55, 41.8%). Seventeen patients (30.9%) admitted the history of mosquito bites. EPA incidence in autumn showed the tendency to increase and reached the peak in 2016. Interestingly, according to the press release, mosquito population in the autumn is increasing steadily. Conclusion: Though more studies are needed to elucidate clear relationship between EPA and mosquito bite, mosquito bite could be the very causative factor of EPA based on the result of this study.
Patch testing with Korean standard series in patients with trachyonychia
( Tae-wook Kim ),( Geun-whi Park ),( Sung-min Park ),( Hyun-joo Lee ),( Hyun Ju Jin ),( Hyang-suk You ),( Woo-haing Shim ),( Gun-wook Kim ),( Hoon-soo Kim ),( Hyun-chang Ko ),( Byung-soo Kim ),( Moon- 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2
Background: Several studies evaluated the histopathologic findings of trachyonychia revealing that spongiotic tissue reaction was most common. In addition, many patients with trachyonychia complain of periungual itching. However, the association of contact allergy in trachyonychia is obscure. Objectives: To evaluate the association of contact allergy in trachyonychia. Methods: We retrospectively analyzed clinical characteristics and the patch test results with Korean standard series in 39 patients with trachyonychia. Results: Twenty-two of 39 patients (56.4%) had positive reactions to one or more allergens. The most commonly detected allergens were nickel sulfate (45.5%), followed by cobalt choloride (31.8%), thimerosal (22.7%), 4-Phenylenediamine base (13.6%), paraben mix (9.1%), balsam of peru (9.1%), p-tert-butylphenol formaldehyde resin (9.1%), quinoline (4.5%), mercury (4.5%), and 5-chloro-2-methyl-4-isothiazolin-3-one (4.5%). The frequency of positive patch test reactions was significantly higher in patients with trachyonychia accompanying periungual itching than in patients with asymptomatic trachyonychia (71.4% versus 18.2%, p<0.005). Conclusion: Though it is hard to decider clinical relevance or not between trachyonychia and positive allergens in this study, we guess that some allergen can have some role to provoke or to aggravate trachyonia especially when the patients with trachyonychia have periungual itching.
다중절편 방사선단층촬영 결과에 기반한 한국 중년 남성에서의 관상동맥 석회화와 심혈관질환 위험인자와의 연관성
박승현(Seung-Hyun Park),김영욱(Young-Wook Kim),채창호(Chang-Ho Chae),김자현(Ja-Hyun Kim),강윤식(Yune-Sik Kang),박용휘(Yong Whi Park),정백근(Baek Geun Jeong) 한국농촌의학 지역보건학회 2014 농촌의학·지역보건 Vol.39 No.1
본 연구는 다중절편 방사선단층촬영을 이용하여 관상동맥 석회화와 심혈관질환 위험인자와의 관련성에 관하여 알아보기 위하여 수행되었다. 이를 위하여 일개 대학병원에서 2010년 1월부터 2011년 12월까지 다중절편 방사선단층촬영을 시행한 30~59세의 성인 남성 5,899명을 대상으로 문진, 설문, 신체계측, 혈액검사 등을 시행하였다. 다중절편 방사선단층촬영 영상을 통해 대상자의 관상동맥 칼슘 점수를 확인하고, 기존의 심혈관질환 위험인자에 대해 확인하였다. 대상자 5,899명의 평균 관상동맥 칼슘 점수는 8.20이었고, 773명(13.1%)에서 관상동맥 석회화가 관찰되었다. 관상동맥 석회화 유무와 알려진 심혈관질환 위험인자(나이, 혈압, 공복혈당, 콜레스테롤, 아포지방단백, 비만)는 유의한 관련성을 보였으며, 심혈관질환 발병 위험도평가도구들과도 유의한 관련성이 있었다. 30-39세, 40-49세, 50-59세의 연령 군에서 관상동맥 석회화와 통계적으로 유의한 관련 요인은 각기 다른 양상을 나타냈다. 본 연구를 통하여 관상동맥 석회화와 전통적인 심혈관질환 위험인자와의 관련성 및 심혈관질환 발병위험도 평가도구와의 관련성을 확인할 수 있었다. 또한 연령 군에 따라 각기 다른 양상의 위험인자를 확인할 수 있었다. 따라서 향후 심혈관질환 예방을 위한 관리전략 수립에 연령에 따른 차이를 고려한 접근이 필요할 것으로 사료된다. Objectives: The objective of this study was to investigate the relationship between coronary artery calcification and risk factors of cardiovascular disease with multidetector computed tomography. Methods: Data were collected from 5,899 males between 30 and 59 years old by interview, survey, physical examination, blood test, and multidetector computed tomography in the university hospital from January 2010 to December 2011. We confirmed the coronary artery calcium scores of subjects by multidetector computed tomography and identified risk factors of cardiovascular disorders. We investigated the relationship between coronary artery calcification and risk factors of cardiovascular disorders. Results: Mean calcium score of the coronary arteries in 5,899 participants was 8.20, and 773 participants (13.1%) exhibited coronary artery calcification. The presence of coronary artery calcification was correlated to risk factors of cardiovascular disease (age, blood pressure, triglyceride, HDL cholesterol, LDL cholesterol, glucose, Apolipoprotein A-1, Apolipoprotein B, body mass index, waist circumference) and risk assessment tools of cardiovascular disorders. Significant predicted factors of coronary artery calcification had different patterns in each age group (30-39, 40-49, 50-59 years old). Conclusions: We confirmed the relationship between coronary artery calcification and either typical risk factors of cardiovascular disease or risk assessment tools of cardiovascular disease. In addition, we also observed that the pattern of these factors varied according to age. Therefore, age-related variation needs to be considered in management strategies to prevent cardiovascular disease.