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약물전달 장치를 위한 Electrohydrodynamic Printing 연구
김진범(Jinbum Kim),황태헌(TaeHeon Hwang),류원형(WonHyoung Ryu) 한국생산제조학회 2011 한국생산제조시스템학회 학술발표대회 논문집 Vol.2011 No.4
One of the major challenges in drug delivery system is to provide an appropriate dosage of therapeutic agents at a right time and location. For this, we have been developing micro-fluidic drug delivery systems comprised of an array of micro-fluidic channels and drug reservoirs. The size of drug reservoirs ranges from 10 ㎛ ~ 1㎜ and the filling the multiple micro-scale reservoirs with drug has been a major challenge. Electrohydrodynamics (EHD) jet printing technology was employed to load drug molecules into micro-scale reservoirs. Rhodamine B was used as a model drug and its controlled loading into micro-scale reservoirs are demonstrated using voltage and a distance between a injection nozzle and a reservoir.