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미생물 증식 공정에서의 기질 저해에 대한 개선된 Haldane 모델의 응용
황영보 한국공업화학회 1998 한국공업화학회 연구논문 초록집 Vol.1994 No.1
This paper deals with the modelling of substrate inhibition in microbial growth processes. For the successful applications and overall model validation in microbial growth processes, a new substrate inhibition model-modified Haldane model-has been developed. Performances are compared on the basis of different experimental data in the literature and, of parameter sensitivity analysis. Finally, the parameter sensitivity analysis emphasizes that the modified Haldane model has a very simple but flexible enough model structure for representing the microbial growth kinetics with limited number of parameters.
심한 비선형적 미생물 증식 공정에 대한 일반화된 미생물 모델 : Part 2. Moser 접근법의 도입 Part 2. Introduction of Moser`s approach
황영보 한국공업화학회 2001 응용화학 Vol.5 No.2
Based on the biokinetic model for the microbial substrate inhibition developed in these serial studies, a modeling study has been carried out to account for the low substrate limitation effects as well as for the substrate inhibition. For the compensation of the low substrate limitation effect, Moser's approach is introduced in several models for substrate inhibition. The performance of these microbial growth models is compared with the available data in the literature.
다중 비경쟁 저해 메카니즘에 근거한 개선된 Haldane모델의 이론적 유도
황영보 한국공업화학회 2002 응용화학 Vol.6 No.1
This paper deals with the theoretical derivation of the modified Haldane model in the microbial growth processes. Based on the biological concepts of substrate-receptor and inhibitor-receptor working mechanisms, a new multiplex non-competitive microbial inhibition mechanism has been considered, which is natural expansion of the single non-competitive inhibition in the enzyme reaction. Finally, modified Haldane model turned out to be well designed with a biological meaningful constant of total inhibition concentration.
미생물 증식 공정에서의 새로운 기질 저해 모델 : 개선된 Aiba 모델식의 응용 Applications of Modified Aiba Model
황영보 한국공업화학회 1998 응용화학 Vol.2 No.2
This paper deals with the modelling of substrate inhibition in microbial growth processes. For successful applications and overall model validation in microbial growth processes, a new substrate inhibition model, modified Aiba model, has been introduced. Performances are compared on the basis of the goodness of fit the parameter sensitivity analysis, and the best- fittings of different experimental data in the literature, respectively, Finally, the modified Aiba model turns out to be a very simple but flexible enough model structure for representing the microbial growth kinetics with limited number of parameters.