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현호봉(Ho Bong Hyun),현혜진(Hye Jin Hyeon),김성천(Sung Chun Kim),고보람(Boram Go),윤선아(Seon-A Yoon),정용환(Yong-Hwan Jung),함영민(Young-Min Ham) 한국자원식물학회 2021 한국자원식물학회지 Vol.34 No.6
Whitening agents derived from natural sources which do not have side effects are sought after. Schizophragma hydrangeoides is an edible plant that grows wild on Jeju Island. We aimed to determine whether S. hydrangeoides extracts show anti-melanogenic activity. Here, we found that 70% ethanol extracts of S. hydrangeoides leaf suppressed α-melanocytestimulating hormone-induced melanogenesis in B16F10 mouse melanoma cells. This activity of anti-melanogenesis in B16F10 cells were investigated by determining melanin content and tyrosinase activity, and by performing western blotting. The 70% ethanol extract downregulated tyrosinase and tyrosinase-related protein 1. In addition, the n-hexane fraction of S. hydrangeoides leaf (HFSH) exhibited significant anti-melanogenic activity among the various solvent fractions tested without reducing the viability of B16F10 cells. Taken together, these results indicate that extracts from S. hydrangeoides leaf can influence cellular processes via modulation of tyrosinase activity. Hence, S. hydrangeoides can be used as a whitening agent in the cosmetic industry and as a therapeutic agent for treating hyperpigmentation disorders in the clinic.
최경혜(Choi, Gyeong-Hye),김현주(Kim, Hyeon-Ju),김주현(Kim, Joo-Hyun),남은숙(Nam, Eun-Sook),현혜진(Hyun, Hye-Jin),강현욱(Kang, Hyun-Wook),윤성자(Yoon, Sung-Ja),손현정(Son, Hyun-Jeong),김현정(Kim, Hyun-Jeong),황아름(Whang, Ah-Rm),김원 한국간호교육학회 2018 한국간호교육학회지 Vol.24 No.1
Purpose: The purpose of this study is to examine and share experiences of male nurses who have been rejected during their nursing practice by their patients. Methods: The participants were 12 male nurses who have worked in several hospitals. Data were collected through personalized in-depth interviews. Collected data were analyzed with the content analysis method. Results: The results can be categorized into three main themes. 1. Rejection based on gender stereotypes of nurses’ roles. 2. Nurses’ reactions when nursing was rejected 3. Reestablishing the role as a nurse. The results of this study showed that male nurses were struggling to maintain their own positions as professional nurses. They were refused by their patients and they experienced a lack of skill and knowledge in nursing practice. They were harmed physically and psychologically from being turned down, and sometimes they had serious conflicts with female nurses. Meanwhile, the male nurses tried to be faithful to their role as professional nurses. Conclusion: The results of this study show the following findings. 1. The male nurses’ experiences where mostly ones of understanding and cooperation with patients’ caregivers. 2. The need for public relations advertising and systematic support from the media. 3. The need for improving gender equality for nurses. 4. Strengthening male nursing students’ endeavors for sound nursing professionalism.