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포스터 발표 : 담도,췌장 ; 췌장암에서의 Clusterin 발현과 세포사멸에 관한 연구
김진용 ( Jin Yong Kim ),이홍식 ( Hong Sik Lee ),김영선 ( Young Sun Kim ),전훈재 ( Hoon Jae Jun ),엄순호 ( Soon Ho Um ),이상우 ( Sang Woo Lee ),최재현 ( Jae Hyun Choi ),김창덕 ( Chang Duck Kim ),류호상 ( Ho Sang Ryu ),현진해 ( Jin 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
〈목적〉 췌장암은 조기 진단이 어렵고 항암제치료 및 방사선 치료에 반응도가 매우 낮아 5년 생존율이 약1-3%에 불과할 정도를 치료가 어려운 종양이다. 췌장암이 일반적으로 항암 치료에 반응이 낮은 이유는 아직 규명되고 있지 않으나 췌장암세포가 항암제 및 방사선 치료에 의해 유발되는 세포사멸에 대한 저항력이 큰 것이 가능성으로 제시되고 있다. Clusterin은 세포사멸, 조직재생, 세포 부착등의 여러 가지 생물학적 기능을 갖고 있는 glycoprotei
이상우,이홍식,강동훈,최재현,현진해,전훈재 대한소화기내시경학회 1995 Clinical Endoscopy Vol.15 No.3
Lymphangiomas are made up of multiple lymphatic channels lined by benign-appearing endothelial cells. The lesions can occur anywhere in the body but most commonly affect head, neck and axilla. It rarely involves the gastrointestinal tract and particularly lymphangioma of the colon is very rare. Histologically,it is classified three types as simple or capillary, cavernous, and cystic. We experienced three cases of cavernous lymphangioma of the ascending colon. Case 1, 56-year-old male, had lymphangioma accompanied by ulcerating cancer of the cecum. Case 2, 51-year-old female, had lymphangioma of cecum. Case 3, 41-year-old male had lymphangioma at ileocecal valve. All cases could be diagnosed by colonoscopic snare polypectomy.
직장 유암종 (Carcinoid Tumor) 에서 내시경 초음파의 임상적 유용성
이상우,최재현,이성준,이홍식,김창덕,류호상,송치욱,진윤태,강창돈,현진해,전훈재,엄순호 대한소화기내시경학회 2000 Clinical Endoscopy Vol.21 No.4
Background/Aims: Carcinoid tumor of the rectum is relatively uncommon lesion with malignant potential, representing 17-27% of gastrointestinal tract carcinoid. The selection of treatment in rectal carcinoid tumor is determined by the depth of invasion and the presence of metastasis. In this study, we evaluated the clinical utility of EUS in selecting the management of the rectal carcinoid tumor. Methods: Total 8 patients witd rectal carcinoid tumor diagnosed by means of colonoscopy and EUS from 1994 to 1999 were included in this study. None had specific symptoms of carcinoid syndrome. The treatment modality of all tumors were selected by EUS before resection. We examined histologic feature after resection of tumors in order to evaluate the effectiveness of EUS. Results: In total 8 patients, the image of tumors was oval to round. The internal echo was generally hypoechoic and homogenous. The margins were clearly visualized, and the contour was somewhat smooth. All tumor were resected completely. The overall accuracy of determining the depth of invasion using endoscopic ultrasonography was 87% (7 of 8 lesions). Conclusions; EUS is considered to be helpful in evaluating the malignant behavior of rectal carcinoid tumor. It is suggested that the criteria of the selection based on the EUS findings is available in the choice of treatment for rectal carcinoid tumor.