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      • SCOPUSKCI등재

        약년자 위암에 대한 검토

        배정동(Jyung Dong Bae),김병곤(Byeong Gon Kim),박정대(Jung Dae Park),김유홍(You Hong Kim),허형호(Hyoung Ho Huh),최재진(Jae Jin Choi),최지용(Ji Yong Choi) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.3

        N/A During 8 year period from January 1981 to December 1988, we have experienced 36 cases of gastric cancer under 35 years of age among 515 cases of all gastric malignancies, which were confirmed by histopathological study at Catholic hospital in Taegu. The results were as follows: 1) Among the gastric malignancies, the incidence of gastric cancer in young adults was 7.0%. 2) Male to female ratio was 1.25 : l 3) Most of the symptoms were nonspecific and epigastric pain or discomfort was the major symptom (72.2%) and others were nausea, vomiting, and hematemesis and so on. 4) Over half of the patients visited hospital within 6 months after onset of symptoms. 5) Physical examination revealed epigastric tenderness, palpable mass, anemia, and abdominal distension in decreasing order of frequency. 6) 61.1% of 36 cases had complications such as bleeding and pyloric obstruction when first seen. 7) All patients were diagnosed preoperatively as gastric cancer with combination of U.G.I. Series and gastrofiberscopic examination, and only gastrofiberscopic examination could diagnose gastric cancer at high accuracy of 93.9%. 8) The major site of tumor location was on the antrum and lesser curvature side. 9) Histopathologic findings revealed that most of the cases (91.7%) were adenocarcinoma and 5 cases were early gastric cancer. 10) Of 28 cases of resectable cancer, 19 cases underwent radical operation for cure.

      • SCOPUSKCI등재

        불우시설 수용인에서 B형 간염 바이러스 표식자에 대한 역학 조사

        오성윤,안기성,허형호,현대성,임달수 대한소화기학회 1992 대한소화기학회지 Vol.24 No.5

        To investigate the seroprevalence of Hepatitis B virus markers in institutionalized population, we surveyed 1670 institutionalized persons who lived in Taegu Hope Village and 1603 controls who visited hospital for general health screening on December,1991. The poisitive rate of HBs Ag io institutionalized population (7.19%) was not significantly higher than that of control (7.05%) (p$gt;0.05). However, by age and sex matched analysis, there were some differences. The occurrence rate of HBs Ag reaches its maximal rate at forth decade, and then decreases with advancing age in institutionalized population as does it in control group, although the peak of the latter occurs a decade later. In institutionalized population there was no sexual difference in the positive rate of HBs Ag (7.02% in men and 7.42% in women), but in control group, male preponderance was seen (8.83% in men and 4.03% in women). In contrast to HBs Ag, the occurrence rate of Anti HBs in institutionalized population (10.78%) was significantly lower than that of control (30.8%) (p$lt;0.05). Female (14.1%) has higher rate of Anti HBs positivity than male (8. 4%) in Institutionalized population, but no such difference was seen in control group. Among HBs Ag positive institutionalized persons, the positive rates of HBe Ag and Anti HBe were 32.7% and 59.3% respectively. After fifth decade, the occurrence rate of HBe Ag constantly decreased with advancing age, but the reverse pattern was seen with Anti HBe.

      • KCI등재후보

        만성 호중구성 백혈병 1 예

        최재진,박정대,김유홍,황기석,허형호,최지용 대한내과학회 1990 대한내과학회지 Vol.39 No.5

        Chronic neutrophilic leukemia is a rare myeloproliferative disorder characterized by a sustained high WBC, which is entirely due to the presence of mature neutrophil, hepatosplenomegaly, high neutrophil alkaline phosphatase score, absence of Philadelphia choromosome, and absence of a ceuse for leukemoid blood picture. A 66-year-old woman was diagnosed as having chronic neutrophilic leukemia. Peripheral blood showed leukocytosis with about 90 percent mature neutrophil and rare immature granulocyte. The neutrophil alkaline phosphatase score was high. A bone marrow study showed hypercellular marrow with neutrophilic hyper plasia. Cytogenetic study was normal, with no evidence of Philadelphia chromosome. The underlying disease which causes 1eukcmoid reacction was not detected. The patient had a hemorrhagic tendency, and a coagulation study showed prolonged aPTT. A coagulation factor assay showed deficiency of factor VIII, IX. The platelet function was abnormal on in vitro study showing failure to aggregate with epinepnrine, ristocetin, collagen, and ADP. The disease was well controlled with hydroxyurea.

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