http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
함인혜(In Hye Ham),왕도미나(Tomina Wang),조은선(Eun Sun Cho),조형권(Hyung Kwon Cho),황완균(Wan Kyun Whang) 대한약학회 2001 약학회지 Vol.45 No.3
The herbaceous species of phyllanthus in this genus are used as hyperglycemic, diuretic, and malaria agent in the world. For the phytochemical studies and the investigation of medicinal resources in the Phyllanthu species, phyllanthus species, (Euphorbiaceae) were used and the studies of constituents in this plant were carried out. From the aqueous fraction of methanolic extract, one flavonoid (quercetin-3-0-rutinoside), two gallotannins(gallic acid, methyl gallate), and two ellagitannins (corilagin, geraniin)were isolated through fractionation and repeated column chromatography using Amberlite XAD-4, ODS gel, and sephadex LH-20. The structures of these compounds were identified on the basis of spectroscopic evidences.
국산 5종 포공영(蒲公英)의 항염 효과 및 성분 함량 비교 연구
최호영 ( Ho Young Choi ),송선호 ( Sun Ho Song ),함인혜 ( In Hye Ham ),부영민 ( Young Min Bu ),김호철 ( Ho Cheol Kim ),이미화 ( Mi Hwa Lee ) 대한본초학회 2010 大韓本草學會誌 Vol.25 No.4
Objectives: Taraxaci Herba et Radix (THR) is widely used as a food and medicinal herb in Korea. It has been used for treatment of virus inflammatory disease, liver diseases and gastritis. So far, anti-inflammatory effects and constituents of various species in THR has not been studied for comparison. The aim of this study is to compare the anti-inflammatory effects of the aerial part and root from various THR. Also, we have compared the contents of its known constituents with each. Methods: In this study, we estimated anti-inflammatory effect and compared their constituent by HPLC. For the determination of anti-inflammatory effects, we investigated NO and PGE2 production by ELISA. The expressions of iNOS was determined by western blotting in LPS-induced RAW 264.7 macrophage cells. And, standard compounds which are methyl gallate, gallic acid, syringic acid and esculetin of THR were analyzed by HPLC using a C18 column. Results: Methanol extracts of THR decreased NO and PGE2 production. The expressions of iNOS protein were also decreased in methanol extracts of THR. As a result, HPLC analysis showed that they showed similar patterns. Methyl gallate and esculetin showed the highest content. Methyl gallate was included over 10% content in each aerial part and root of THR. Conclusions: These results indicate that most of THR distributed in Korea might represent therapeutic agent for treatment of inflammatory diseases.
진피류(陳皮類) 한약재의 Hesperidin과 정유성분 비교
함인혜 ( In Hye Ham ),정의동 ( Eui Dong Jung ),이경진 ( Kyung Jin Lee ),이제현 ( Je Hyun Lee ),부영민 ( Young Min Bu ),김호철 ( Ho Cheol Kim ),최호영 ( Ho Young Choi ) 대한본초학회 2008 大韓本草學會誌 Vol.23 No.4
Objectives: This study was carried out to evaluate the quality of the peels of various Citrus species. Method: The contents of hesperidin from fruit peels used as Citri Pericarpium such as C. natsudaidai, C. grandis, C. unshiu, and C. sunki were analyzed by HP-TLC, HPLC, and essential oils of those were analyzed by GC/MS. Results: HPLC analysis showed that the hesperidin from the peel of C. unshiu and C. reticulata was satisfied the standard of Korean Pharmacopoeia. The essential oil was analyzed by GC/MS. As a result, limonene, furfural, 5-methyl-2-furfural, linalool oxide(cis), linalool oxide(trans), terpinen-4-ol, (-)-α-terpineol, germacrene D, 4-methyl-2,6-di-tert-butylphenol was detected in all 4 kinds of Citrus species. Conclusions: As a result of chemotaxonomical similarity analysis with essential oils, the peels of C. natsudaidai and C. grandis are closely related, while C. unshiu is distantly related to the others.
함인혜(In Hye Ham),김일혁(Il Hyuk Kim) 대한약학회 1994 약학회지 Vol.38 No.4
As one of the studies for Korean cultivated Rhubarb, which has been used stomachic bitter, laxative and purgative, etc, MeOH extract of the leaves was fractionated with ether, ethylacetate. From the ether fraction of MeOH extract, two anthraquinone derivatives, 1,6,8-trihydroxy-3-methyl anthraquinone(emodin, C15H10O5), 1,6,8-trihydroxy-3-hydroxymethyl anthraquinone (citrerosein, C15H10O6) and from the ethyl acetate fraction of MeOH extract, one anthraquinone derivative, emodin-8-beta-D-glucopyranoside(C2lH20010) were isolated and identified through the physico-chemical properties and spectroscopic evidences(UV, IR, NMR, Mass), respectively.
황완균,오인세,함인혜,한덕룡,Whang, Wan-Kyunn,Oh, In-Se,Ham, In-Hye,Hahn, Dug-Ryong 한국생약학회 1994 생약학회지 Vol.25 No.2
For the investigation of medicinal resource in Phyllanthus ussuriensis, the studies were conducted to evaluate the pharmaco-constituents in Phyllanthus ussuriensis, which is used as folk medicine in China. From the hot water extract of leaves, three phenolic compounds were isolated and identified as phloroglucinol, gallic acid and rutin by physico-chemical properties and spectroscopic evidences$(IR,{\;}^1H-NMR,{\;}^{13}C-NMR{\;}and{\;}Mass,{\;}etc.)$.