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유지혈액투석 환자에 있어 영양상태와 염증지표의 관계에 대한 연구
한상엽(S. Y. Han),조상경(S. K. Jo),윤종우(J. W. Yoon),신진호(J. H. Shin),이소영(S. Y. Lee),차대룡(D. R. Cha),권영주(Y. J. Kwon),조원용(W. Y. Cho),표희정(H. J. Pyo),정태시(T. S. Jung) 대한신장학회 2000 Kidney Research and Clinical Practice Vol.19 No.2
N/A Malnutrition is known to be an independent risk factor of morbidity and mortality in hemodialysis patients. The causes of malnutrition were obsucure. Several catabolic cytokines such as interleukin-1β(IL-1β), interleukin-6(IL-6), and tumar necrosis fac-tor-α(TNF-α) were reported to be elevated in hemo-dialysis patients with malnutrition, To evaluate the nutritrional status and relationship among cytokines IL-1β, TNF-α, and various parameters, we performed a cross-sectional study in maintenance hemodialysis patients who have undergone for six months at least. Patients who were taking steroid. showed any sign of infection, or had residual renal function were excluded from the study. Nutritional status was classified into well nourished(A), mild to moderate malnutrition(B), and severe malnutrition(C) by using subjective global assessment(SGA). Patients were divided into two groups (I: A, II: B and C) based on SGA. The level of IL-10, TNF-a were estimated by ELISA. Total patients were 23(M/F:15/8 mean age 52.0±1.56yrs). There were significant differences in weight changes for 6 months, CRP, and SGA between two groups based on the level of serum albumin(using 4.0g/dL as a cutoff value). Moreover, based on SGA, there were significant differences in age, BMI, CRP, and albumin between the group I and IL Serum albumin levels was directly correlated with transferrin(r=0.302, p=0.04), and was inversly correlated with age(r=-0.329, p=0.007). TNF- u was inversly correlated with Kt/Vueea(r=-0.291, p= 0.047), and directly correlated with the duration of maintenance hemodialysis(r=0,346, p=0.036), BMI(r-0.453, p<0.05). These data support the fact that albumin and CRP can be a good marker of nutritional status in maintenance hemodialysis patient. However cytokines and transferrin might not be related to nutritional status.
이희준(H. J. Lee),한상엽(S. Y. Han),정용갑(Y. G. Chung),조남경(N. K. Cho),길경섭(G. S. Kil),김영목(Y. K. Kim) 한국전산유체공학회 2004 한국전산유체공학회지 Vol.9 No.3
A heated and expanded helium is used to pressurize liquid propellants in propellant tanks of propulsion system of liquid propellant launch vehicles. To produce a heated and expanded helium, an hot-gas heat exchanger is used by utilizing heat source from an exhausted gas, which was generated in a gas generator to operate turbine of turbo-pump and dumped out through an exhaust duct of engine. Both experimental and numerical approaches of hot-gas heat exchanger design were conducted in the present study. Experimentally, siliconites - electrical resistance types - were used to simulate the full heat condition instead of an exhausted gas. Cryogenic heat exchangers, which were immersed in a liquid nitrogen pool, were used to feed cryogenic gaseous helium in a hot-gas heat exchanger. Numerical simulation was made using commercially utilized solver - Fluent V.6.0 - to validate experimental results. Helically coiled stainless steel pipe and stainless steel exhausted duct were consisted of tetrahedron unstructured mesh. Helium was a working fluid inside helical heat coil and regarded as an ideal gas. Realizable k-ε turbulent modeling was adopted to take turbulent mixing effects in consideration. Comparisons between experimental results and numerical solutions are presented. It is observed that a resulted hot-gas heat exchanger design is reliable based on the comparison of both results.
한상엽,박태수,오민응 大韓神經精神醫學會 1972 신경정신의학 Vol.11 No.3
The authors sketche some of the psychodynamic considerations and psychoanalytic significances occuring crisis situations, including work disorders. The psychopath underlying symptoms of homosexual determines and maintains the homosexual adaptation itself. The authors studied the outcome of the homosexual male who had exhibited feminine behavior and markedly revealed castrative wish. A structured interview, devised by culling from the literature those factors considered to be associated with gender identity disturbances. This homosexual suggests that those with the earlier age of onset are more likely to develop severe gender identity disturbances.