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RISS 인기검색어
- 검색키워드
- 저자 : 한문희 ( Myung Ja Choi (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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The Evaluation of T/E and T/LH Ratios in Athelete's Urine by the Radioimmunoassay Methods
최명자,강혜경,정태화,박종세,한문희,Choi, Myung-Ja,Kang, Hea-Kyung,Chung, Tai-Wha,Park, Jong-Sei,Han, Moon-H. 생화학분자생물학회 1987 한국생화학회지 Vol.20 No.3
Anabolic steroid를 정상인에게 투약하면 testosterone/epitestosterone(T/E) 비율과 testosterone/leutenizing hormone(T/LH) 비율은 상승된다고 보고된 바 있다. 위와같은 보고를 근거로, 1986년도 제 10회 아시아 경기에 입상한 선수 및 그 후보선수의 뇨를 검체로 하여 RIA를 이용한 testosterone(T)과 epitestosterone(E) leutenizing hormone(LH)의 정량분석을 수행했으며, T/E, T/LH의 정상치 및 그 분포도를 확립하였다. 또한 T/E와 T/LH의 상관관계를 조사한 결과 T/E와 T/LH가 정상범위에 속할 경우에는 T/E가 높은 값을 갖더라도 T/LH가 반드시 높은 것으로 나타나지는 않았다. 이번에 사용한 RIA방법은 강도가 매우 높고 광범위한 농도에 걸쳐서 교차 반응없이 T와 E를 각각 정량적으로 측정할 수 있음을 확인하였다. The studies reported that the urinary ratios of testosterone/epitestosterone(T/E) and testosterone/leutenizing hormone(T/LH) were increased significantly by the administration of anabolic steroids to normal subjects. Based on the report above, the T/E and T/LH ratios were investigated by a RIA method for the 194 urine specimens of the Asian Games atheletes. The normal distribution of the testosterone(T), epitestosterone(E), and leutenizing hormone(LH) values were established and the T/E and T/LH ratios were investigated for steroid doping control. The correlation study between the T/E and T/LH ratios indicates that the high T/E ratio is not necessarily associated with the high T/LH ratio within the population who have the normal values of the TIE and T/LH ratios. It was also found that the RIA performances of T and E assays were very sensitive and could quantitatively detect the T and E respectively without cross-reaction. The standard curve range covers a broad range of steroid values.
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방사면역학적 측적방법을 이용한 운동 선수들의 뇨중 T / E , T / LH 비율 측정 검사
최명자,강혜경,정태화,박종세,한문희 ( Myung Ja Choi,Hea Kyung Kang,Tai Wha Chung,Jon Gsei Park,Moon H . Han ) 생화학분자생물학회 1987 BMB Reports Vol.20 No.3
The studies reported that the urinary ratios of testosterone/epitestosterone (T/E) and testosterone/leutenizing hormone(T/LH) were increased significantly by the administration of anabolic steroids to normal subjects. Based on the report above, the T/E and T/LH ratios were investigated by a RIA method for the 194 urine specimens of the Asian Games atheletes. The normal distribution of the testosterone(T), epitestosterone(E), and leutenizing hormone(LH) values were established and the T/E and T/LH ratios were investigated for steroid doping control. The correlation study between the T/E and T/LH ratios indicates that the high T/E ratio is not necessarily associated with the high T/LH ratio within the population who have the normal values of the T/E and T/LH ratios. It was also found that the RIA performances of T and E assays were very sensitive and could quantitatively detect the T and E respectively without cross-reaction. The standard curve range covers a broad range of steroid values.
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