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쌍금탕의 약효에 관한 연구(제3보) : 항염증작용에 관하여
한대석(Dae Suk Han),김일혁(Il Hyuk Kim),황규용(Kyu Yong Whang) 한국생약학회 1984 생약학회지 Vol.15 No.4
The extract of Ssangkum-tang was investigated on antiinflammatory activities. The extract showed antiedematous action at a dose of 500㎎/㎏ po in carrageenin edema test in rats. The extract also inhibited the leakage of pontamine sky blue into peritoneal cavity in mice at the doses of 300 and 500㎎/㎏ po.
쌍금탕의 약효에 관한 연구 (제2보) : 급성위염 및 궤양에 대하여
한대석(Dae Suk Han),고건일(Kun Il Ko),김재백(Jae Baik Kim) 한국생약학회 1984 생약학회지 Vol.15 No.4
The effects of Ssangkum-tang on the acute gastritis and the gastric ulcer caused by acetic acid were studied. The water extract improved the inflammation of the acute gastritis and decreased the diameter of the ulcer area.
3,3`,4,4`,5-pentachlorobiphenyl (PCB126)이 Sprague-Dawley랫드의 proteome 발현에 미치는 영향
한대용 ( Dae Yong Han ),강상림 ( Sang Rim Kang ),박현수 ( Hyeon Soo Park ),박광일 ( Kwang Il Park ),원청길 ( Chung Kil Won ),조재현 ( Jae Hyeon Cho ),김석 ( Suk Kim ),이후장 ( Hu Jang Lee ),김은희 ( Eun Hee Kim ),김곤섭 ( Gon Sup 한국수의공중보건학회 2008 예방수의학회지 Vol.32 No.3
한국산 생약의 약리작용 및 독성연구 (제4보) : 급성독성 및 항암작용
장일무(Il-Moo Chang),김제훈(Jae-Hoon Kim),한대석(Dae-Suck Han) 한국생약학회 1982 생약학회지 Vol.13 No.2
Fiftythree species (35 families and 52 genera) of Korean medicinal plants which have been frequently used in oriental herb prescriptions or have been used as folklorics were evaluated on their short term acute toxicity and potential antitumor activities against P-388 murine lymphocytic leukemia model in vivo. Among these plants Acorus gramineus (Araceae), Agrimonia pilosa (Rosaceae), Aralia elata (Araliaceae), Dryopteris crassirhizoma (Aspidiaceae), Syringa reticulata (Oleaceae) and Calystegia japonica (Convolvulaceae) exhibited potent acute toxicity resulting from severe weight loss and death. Agrimonia pilosa (Rosaceae) showed about 33% of increased life span in comparison with that of control group mouse, but others exhibited no significant antitumor activities.
목질진흙(상황)버섯과 동충하초 투여가 운동 시 혈중 피로요인 변화와 항산화체계에 미치는 영향
백일영,한대석,박태선,곽이섭,서상훈,진화은,김영일,우진희,Paik, Il-Young,Han, Dae-Seok,Park, Tae-Sun,Kwak, Yi-Sub,Suh, Sang-Hoon,Jin, Hwa-Eun,Kim, Young-Il,Woo, Jin-Hee 한국생명과학회 2006 생명과학회지 Vol.16 No.7
The purpose of this study was to investigate the effects of p. Linteus and C. militaris supplement on lactate, phosphorous, ammonia, MDA(malondialdehyde), GPX(glutathione peroxidase) and TAS(total antioxidant status) following $VO_{2max}$, and 85% $VO_{2max}$ exercise. The 15 male college students were divided into three groups: 5 P. liteus supplied(PL), 5 C. militaris supplied(CM), and 5 placebos supplied(PB) and compared the differences between supplement before and after. Obtained results were as follows: In the exercise performance time, there were no differences in PL, CM and PB groups. Regular supplement of P. linteus or C. militaris partially reduces fatigue induction factors. Also, P. linteus or C. militaris supplement decreases MDA, increases GPX and TAS. Therefore, it can be concluded that P. linteus or C. militaris supplement not only have a pharmacological effect for clinical treatment, but also have a maintenance effects on the tissue oxidant-antioxidant system after exercise. 본 연구는 인체를 대상으로 목질진흙버섯과 동충하초 투여 후 운동과 회복 중 피로유발 지연과 항산화 방어 효과를 규명하는데 목적이 있었으며, 남자 대학생 15명을 대상으로 목질 진흙버섯 투여군(PL), 동충하초 투여군(CM), 그리고 위약 투여군(PB) 등 세 그룹으로 나누어 6주간 해당음료 100ml/day을 구강으로 투여하였고, 투여 전과 후 운동수행에 따른 차이를 비교하였다. 분석결과 운동수행시간에는 차이가 없었지만, 운동수행에 따른 PL군과 CM군의 피로물질 축적이 부분적으로 감소됨을 보였으며, 지질과산화 생성량은 감소되었고, 항산화효소 활성은 향상됨을 나타냈다. 따라서, 목질진흙버섯과 동충하초는 임상치료 목적의 약리작용 뿐만 아니라, 운동 시 에너지 동원과 피로물질 제거, 그리고 조직의 항산화 방어 역량 향상에 효과가 있다고 사료된다.
강구민 ( Gu Min Kang ),한대일 ( Dae Il Han ) 경상대학교 법학연구소 2014 法學硏究 Vol.22 No.4
It has been six years since the System of Citizen Participation Criminal Trial has been adopted in an attempt to establish reliable judicial system by enhancing judicial democratic legitimacy and clarity in 2008. The complete format and structure were supposed to be established during the trial period over first five years since the adoption, however, it is still in progress and the recent case on the violation of election law ignited the debate on the System of Citizen Participation Criminal Trial. In particular, ‘Nakkomsu’ and ‘Ahn Do Hyun’ cases, considered politically sensitive, have garnered considerable attention from the mass media so that it may be difficult to expect fair verdict because of the possible prejudices by jury. Further, it has been argued that the Citizen Participation Criminal Trial is not appropriate for politically sensitive cases and they should not be subject to the Citizen Participation Criminal Trial because jury’s political orientation or personal background may hinder their fair decision making. Under existing law, the Citizen Participation Criminal Trial is conducted only if it is requested by defendant. Thus, it is likely to infringe on the defendant’s rights of the request for the Citizen Participation Criminal Trial if the Citizen Participation Criminal Trial is not allowed despite the request from the defendant. For the two cases as mentioned above, there was no exclusion decision by the court and it can be elicited that the court found it appropriate to conduct the Citizen Participation Criminal Trial for the cases. The limitatios of existing jury system, particularly those that are highlighted in ``Nakkomsu`` and ``Ahn Do Hyun`` cases include the scope of cases, composition of jury, and method of verdict. First, it is argued that the political cases that draw high levels of attention, as seen in ``Nakkomsu`` and ``Ahn Do Hyun`` should be excluded from the citizen Participation Criminal Trial, Second, the composition of jury should be reconsidered whe there is a possibility of unfair verdict due to political orientation or emotional appeal. Lastly, the unanimous decision is more adequate for a criminal trial than majority vote whict facilitates judgment in a civil trial. Further, a presiding judge should not be bounded by verdict by jury ig it were affected by public opinin. This study seeks to delve into the limitations of the Citizen Participation Criminal Trial and provide improving strategies.
대퇴사두근-보존형[Quadriceps-Sparing] 최소 침습 슬관절 전치환술의 방사선학적 평가
유주형(Ju-Hyung Yoo),한대용(Dae-Yong Han),한창동(Chang-Dong Han),오현철(Heun-Cheul Oh),고일현(Il-Hyun Koh) 대한정형외과학회 2006 대한정형외과학회지 Vol.41 No.3
목적: 대퇴사두근-보존형(Quadriceps-Sparing) 최소 침습 슬관절 전치환술의 방사선학적인 결과를 기존 수술 방법과 비교 분석하고자 한다. 대상 및 방법: 2004년 3월부터 1년간 전향적으로 대퇴사두근-보존형 최소 침습 슬관절 전치환술을 시행한 50예 (제1군)와 기존의 수술방법으로 시행된 50예(제2군)를 대상으로 하였으며, 모든 예에서 Nexgen LPS-flex Total Knee System (Zimmer, Warsw, IN)을 사용하였다. 각 군에 대하여 수술 전후 대퇴 경골각, 경골 삽입물의 각도, 경골 절단면과 경골 삽입물 크기의 비를 측정하여 경골 삽입물 크기의 적정성을 비교 분석하였다. 결과: 양 군에서 수술 후 경골 삽입물의 정렬 각도 및 후방 경사각, 경골 삽입물의 크기, 출혈량에는 차이가 없었으며(p>0,05), 수술 후 8주 후에 측정한 슬관절 운동범위, 슬관절 점수는 제1군이 제2군에 비하여 양호하였다(p<0.05). 수술 후 대퇴 경골각은 제l군에서 6.9±1.3° 외반, 제2군에서 7.7±1.4° 외반으로 의미 있는 차이가 있었다(p<0.05). 결론: 대퇴사두근-보존형 최소 침습 슬관절 전치환술이 기존의 수술 방법에 비하여 경골 삽입물의 정렬 및 크기 선택은 차이가 없었으나, 대퇴골 원위부의 외반 절골각이 감소하는 경향이 있는 것으로 생각된다. Purpose: The purpose of this study was to evaluate the radiological results of quadriceps-sparing total knee arthroplasty. Materials and Methods: 50 consecutive total knee arthroplasties with a quadriceps-sparing surgical technique and 50 consecutive total knee arthroplasties with conventional surgical techniques were performed. The same surgeon performed all the operations with the same type of prosthesis (Nexgen LPS-flex Total Knee System). We compared the differences between these groups in terms of preoperative and postoperative femorotibial angles, tibial component alignment angles, tibial component inclinations, and ratios of size of the tibia component to tibial cutting size. Results: There were no differences in preoperative femorotibal angles, tibial component alignment angles, tibial component inclinations, ratios of sizes of tibia tray to tibial cutting size, and blood loss between the two groups (p>0.05). The average ranges of motion and HSS scores at 8 weeks postoperatively in the quadriceps-sparing total knee arthroplasty group were greater than those in the conventional surgical technique (p < 0.05). The mean postoperative femorotibial angle in the quadriceps-sparing total knee arthroplasty group was a valgus of 6.9±1.3° compared with a valgus of 7.7±1.4° in the standard arthroplasty group (p < 0.05). Conclusion: A quadriceps-sparing total knee arthroplasty offers predictable results in terms of radiological comparison with the conventional arthroplasty technique. But this technique has the tendency of producing a decreased valgus angle at the distal femur.