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코이치 한국자원식물학회 1990 한국자원식물학회지 Vol.3 No.2
Now, many anticancer drugs are applying in the clinical side, but there is no conclusive effect of such a chemotherapy. Development ofnovel clinical useful anticancer drugs would be dependenton the screen-ing system and its test sample sources. So, it is necessary to outlinesome background on the tumor systems which have been used for screen-ing. This paper describes mainely on National Cancer Institute (NCI)program for anticancer screening systems, because the large number ofcompounds have been screened at NCI prograB and their relationship ofassesment between experimental animals and clinical Patients has beendiscussing and the uniform screefing protocols for various tumorsystens. At the end of this paper, some literatures of antitunor substances from various higher Plants at our laboratory are showed.
코이치 한국자원식물학회 1992 한국자원식물학회지 Vol.5 No.2
Present anticancer drugs in the clinical side have not showed a conclusive effect of the chemotherapy for cancer patients. In order to find much more efficient antitumor agents fromnatural resources, various screening methods vivo and in vitro have been developed by manyresearchers. The intention of this paper is to provide an outline of some background on the tumorsystem in drug development of natural products, to review some screening programs for theevaluation of antitumor activity and to introduce the practical procedures of some antitumorscreening methods in vivo and in vitro. At the end of this paper, the current literatures related toantitumor natural products from higher plants at our laboratory are described.Key words'anticancer drugs, screening methods.
Hydrolysis of Biopex-R-allografts cement and the osteoblastic response to the cement
Shunro Yamaguchi,Takuya Nomoto,Tohru Sekino,코이치니하라 한양대학교 세라믹연구소 2004 Journal of Ceramic Processing Research Vol.5 No.1
A composite of clinically used Biopex-R and allografts was hydrolyzed in calf serum to obtain hydroxyapatite (HAP), while Biopex-R was hydrolyzed in calf serum to obtain octacalcium phosphate (OCP) and HAP. The products from Biopex-Rallografts composite as well as the Biopex-R exhibited rough surfaces. After the hydrolysis, MC3T3-E1 cells were cultured on the Biopex-R-allografts composite. Adherence of cells on Biopex-R-allografts composite is greater in number than on the Biopex-R. The composition of the resulting products affected the cell growth.
Preparation of copper nanoparticles with an organic coating by a pulsed wire discharge method
K. Murai,Y. Watanabe,Y. Saito,T. Nakayama,H. Suematsu,W. Jiang,K. Yatsui,심광보,코이치니하라 한양대학교 세라믹연구소 2007 Journal of Ceramic Processing Research Vol.8 No.2
In the pulsed wire discharge method, a coating technique to prepare metal nanoparticles covered with organic matter has been investigated. Copper nanoparticles covered with organic matter have been successfully prepared by evaporation of a copper wire in an oleic acid vapor/mist. The thickness of the coating layer was a few nanometres. The median diameter of the powder was 25 nm, and became 10 nm smaller than that without the coating because of the inhibition of particle growth by the formation of the coating. From phase identification by transmission electron microscopy and X-ray diffraction analysis, it was found that the copper nanoparticles have been passivated and have not been oxidized in over 2 months. In the pulsed wire discharge method, a coating technique to prepare metal nanoparticles covered with organic matter has been investigated. Copper nanoparticles covered with organic matter have been successfully prepared by evaporation of a copper wire in an oleic acid vapor/mist. The thickness of the coating layer was a few nanometres. The median diameter of the powder was 25 nm, and became 10 nm smaller than that without the coating because of the inhibition of particle growth by the formation of the coating. From phase identification by transmission electron microscopy and X-ray diffraction analysis, it was found that the copper nanoparticles have been passivated and have not been oxidized in over 2 months.
일본근세후기의 질서 정당화논리 -“관습(慣習)”, “고례(古例)”와 법원(法源)에 대한 의식
마츠다코이치로 ( Koichiro Matsuda ) 다산학술문화재단 2008 다산학 Vol.- No.13
This article focuses on the concepts of “convention” and “case” in legal and political discourse in the late eighteenth to the early nineteenth-century Japan in order to shed new light on the early modern legal philosophy in the East Asian region. General view would maintain that the idea of rule of law and the consciousness of proper source of law were introduced to Asian countries after an encounter with European legal thought in the mid-nineteenth century. However, a number of examples from Japanese legal documents and political literature since the late eighteenth century shows that, even though almost no formal education for the legal profession was established under the Tokugawa regime, the consideration of and discussion on the meaning of “convention” and “case” in the legal process constituted important issues. Moreover, the reflective discourse on “the proper source of judicial process” in the early modern period affected the understanding of Western legal thought when the Meiji government adopted the Western judicial system after the Meiji Restoration.