형광물질을 적용한 2개의 발광층을 가진 백색유기발광소자의 제작과 광학적 특성

김유현(You-Hyun Kim),최 재 윤(Jea Yoon Choi),이수환(Su Hwan Lee),윤현수(Hyun Soo Yoon),서지훈(Ji Hoon Seo),서지현(Ji Hyun Seo),박정현(Jung Hyun Park),김영관(Young Kwan Kim),김우영(Woo Young Kim) 호서대학교 공업기술연구소 2007 공업기술연구 논문집 Vol.26 No.1

White organic light-emitting diodes (WOLEDs) with multi-emissive layer structure using two color fluorescent materials is fabricated. WOLED device is composed of ITO / NPB (50nm) / DPVBi (6.5nm) / MADN : DCM2 - 0.5% (17nm) / Bphen (30nm) / Liq (2nm) / Al (lOOnm). DCM2 was functioned as red fluorescent dye under MADN of red host material while DPVBi worked as blue emitting material in this structure. To obtain best white CIE color coordinate of (0.33 , 0.33),thicknesses of DPBVi and MADN was changed as varying DCM2’s concentration according to color shift in EL spectra. Optimized WOLED device shows emission efficiency of 5.04 cd/A, current density of 18.6 mA/cm2 and luminance of 940 cd/m2 at 6 V with CIE color coordinate, (0.34, 0.33). These results indicates that DPVBi layer effects on hole blocking and control of the exciton due to difference of energy level in highest occupied molecular orbital.

FCA 에 의한 염증 유발 후 주입된 L - NAME 이 기계적 통각과민에 미치는 영향

김민경(Min Kyung Kim),최 윤(Yoon Choi),공현석(Hyun 대한통증학회 1999 The Korean Journal of Pain Vol.12 No.2

N/A Background: Effect of nitric oxide on the hyperalgesia induced by inflammation is controversial. From our previous experiment, NOS inhibitor, L-NAME given during the induction period decrease mechanical hyperalgesia occured by Freund's complete adjuvant induced inflammation. In addition, we attempted to analyze the effects of L-NAME on mechanical hyperalgesia after the development of inflammation by Freund's complete adjuvant in rat paw. Methods: Male Sprague Dawley rats were divided into four groups; control (normal saline), and three different doses of L-NAME (0.1 mg, 1 mg, 10 mg). Inflammation was induced in rats by injecting 0.15 ml of Freund's complete adjuvant (FCA) intraplantarly. Rats showed typical hyperalgesia within twelve hours after injection and maintained this for about one week. Tests were done 2 days after injection of FCA. After the baseline test either L-NAME or saline was injected under light halothane anesthesia. Effect of L-NAME on hyperalgesia was assessed by measuring mechanical hyperalgesia at 15, 30, 60, 90, 120 minutes. Same experients were repeated on normal rats. Results: When injected at the site of inflammation, L-NAME caused dose dependent decrease in mechanical hyperalgesia. However, normal rats also showed increased mechanical threshold after L- NAME injection. Conclusions: Although L-NAME reduces FCA induced mechanical hyperalgesia, this result may solely be due to inhibition of nitric oxide production and need to be further determined.

정상 성인에서 구혈대에 의한 신경기능의 변화

전희정(Hee Jeong Jun),최 윤(Yoon Choi),정헌석(Heon 대한통증학회 1999 The Korean Journal of Pain Vol.12 No.1

N/A Background: Tourniquet pain has important impacts an anesthesia. Tourniquet pain and accom- panying cardiovascular changes are important factors that make patients in distress during anesthesia. As tourniquet pain may be modified by anesthesia, a study on the changes in the neural functions by tourniquet inflation in normal volunteers is important. Methods: Time-dependent changes in tourniquet pain, heart rate, phantom limb sensation, motor function, pain to pressure on upper extremity of 10 healthy and unpremedicated volunteers were mea- sured. Each parameter were measured every 5 minutes starting from 10 minutes before inflation to 15 minutes after deflation of tourniquet. Tourniquet was deflated when the subject felt unbearable pain (score 100 with visual analog scale). Results: Subjects manifested time-dependent pain responses to tourniquet inflation, characterized by increase in VAS, systolic and diastolic blood pressure. Mean duration of tourniquet inflation was 36.4 minutes, volunteers experienced motor paralysis at 27.6 minutes and sensory loss at 33.1 minutes. Pain to pressure decreased over time in both arms. The degree of decrease was greater in the arm on which tourniquet was applied than that in the non-applied arm. Phantom limb sensation occurred in 3 subjects. Conclusions: This study demonstrated dynamic changes in the neural functions during tourniquet inflation period. Tourniquet-induced pain and resultant hypertension occurred in all subjects. Appropriate anesthetic management is needed for the surgery using tourniquet.

L - NAME 에 의한 쥐의 발바닥에서 Freund's Complete Adjuvant 에 의해 유발된 통증 억제

이 청(Cheong Lee),최 윤(Yoon Choi),송명희(Myung He 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.2

N/A Background: Effect of nitric oxide on the hyperalgesia induced by inflammation is controversial. We attempted to find out the peripheral effects of nitric oxide (NO) on hyperalgesia induced by Freund's eomplete adjuvant (FCA) induced inflammation. Methods: Male Sprague Dawley rats were divided into three groups; control, low dose NG-nitro- L-arginine methyl ester (L-NAME, 500 ug), high dose L-NAME (5 mg). Inflammation was induced by injecting 0.l ml of PCA intraplantarly, which shows typical hyperalgesia within twelve hours after injec- tion and maintamed for about one week. Drugs were injected 2 hours before, just before, and 3, 6, 9, 12 hours after the injection of FCA. Effect of L-NAME on hyperalgesia was assessed by measuring mechanical hyperalgesia and spontaneous pain for 3 days. Results: When injected at the site of inflammation, L-NAME caused dose dependent reduction of sponlaneous hyperalgesia. Mechanical hyperalgesia was also reduced by high dose L-NAME (p<0.05). After syslemic injection of high dose L-NAME in the back, no significant difference was noticed. Conclusions: This suggest that L-NAME reduces FCA induced hyperalgesia via peripheral action.

피해자의 단상: 내러티브 연구를 통한 알코올 중독가정 자녀의 삶의 재구성

오세일(Oh, Seil),최 윤(Choi, Yoon),강선경(Kang, Sun-Kyung) 한국피해자학회 2019 被害者學硏究 Vol.27 No.1

본 연구는 알코올 중독가정에서 성장한 한 알코올 중독회복자의 삶의 이야기를 내러 티브 연구를 통해 재구성하였다. 알코올 중독자 아버지와 극심한 우울증 어머니 사이에서 평생을 살아온 내러티브 주인공의 이야기 분석을 통해 알코올 중독가정의 “피해자”로 대표되는 경험을 다룸으로써, ‘시간’이라는 연속성과 물리적 화자의 ‘공간’, 그리고 화자와 사회와의 ‘상호작용’의 맥락 속에서 피해자의 이야기가 어떻게 재구성되는지 탐색해 보았다. Clandinin과 Connelly(2002)가 채택한 분석방법을 통해 화자의 내러티브를 재구 성한 결과, 피해자의 단상은 “쓸쓸함과 두려움의 그림자”, “사랑받고 기대고 싶었던 소년”, “감추고 싶은 자아”, “거울 속 비친 나의 모습”, “사라지지 않는 부모 그림자”, “뿌리 깊은 나무”의 주제로 도출되었다. 알코올 중독문제를 개인차원으로 바라보는 국내 현실을 반영하여, 중독가정을 피해자의 관점에서 바라보는 사회적 인식으로의 변화 등을 사회복지 실천 및 정책적 논의로서 제시하였다. This study reconstructed the story of the life of a male alcohol addicted restorer who grew up in a family with alcoholic through narrative research. By analyzing the story of a narrator who has lived a lifetime between a father of alcoholism and a mother of extreme depression, the experience of being represented as a victim of alcoholism can be analyzed in terms of the continuity of ‘time’, the ‘space’ of the physical speaker, in the context of ‘interaction’ with society, tried to find out if the story of the victim is reconstructed. Through the analysis procedure adopted by Clandinin and Connelly (2002), the narrative of the narrator was reconstructed. The result of the reconstruction of the narrator was that “the shadow of despair and fear”, “the boy who wanted to be loved and leaned”, “my appearance on the mirror”, “the spirit of parents who are not lost” and “the deep-rooted tree”. study suggests the change alcoholic and alcoholic’s children to the social awareness of the addicted family from the viewpoint of the victim, reflecting the reality of the domestic society.

신경병증성통증 모델쥐에서 뇌간핵 부위에 미세 주입한 Bicuculline에 의한 척수후각세포의반응도 억제

임중우(Joong Woo Leem),최 윤(Yoon Choi),이재환(Jae 대한통증학회 1998 The Korean Journal of Pain Vol.11 No.1

N/A Background: The present study was conducted to investigate effects of mieroinjection of bicuculline, GABA-A receptor antagonist, into the brain stem nuclei on the dorsal horn neuron responsiveness in rats with an experimental peripheral neuropsthy. Methods: An experimental neuropathy was induced by a unilateral ligation of L5-L6 spinal nerves of rats. After 2-3 weeks after the surgery, single-unit recording was made from wide dynamic range (WDR) neurons in the spinal cord dorsal horn. Results: Responses of WDR neurons to both noxious and innocuous mechanical stimuli applied to the somatic reeeptive fields were enhanced on the nerve injured side. These enhanced responsiveness of WDR neurons were suppressed by microinjection of bicuculline into periaqueductal gray(PAG) or nucleus reticularis gigantocellularis(Gi). A similar suppression was also observed when morphine was microinjected into PAG or Gi. Suppressive actian by Gi-bicuculline was reversed by naloxonazine, p -opioid receptor antagonist, microinjected into PAG whereas PAG-bicuculline induced suppression was not affected by naloxonazine injection into Gi. Gi-bicuculline induced suppression were reversed by a transection of dorsolateral funiculus(DLF) of the spinal cord. Conclusions: The results suggest that endogenous opioids, via acting on GABAergic interneurons in PAG and Gi, may be involved in the control of neuropathic pain by activating the descending inhibitory pathways that project to the spinal dorsal horn through DLF to inhibit the responsiveness of WDR neurons.