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D-penicillamine 투여력이 없는 전신경화증-쇼그렌 증후군 환자에서 발생한 중증근육무력증
이찬희 ( Chan Hee Lee ),최유리 ( Yu Ri Choi ),김선정 ( Sun Jung Kim ),조정희 ( Jeong Hee Cho ),차민섭 ( Min Seob Cha ),곽민섭 ( Min Seob Kwak ),최일생 ( Il Saeng Choi ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.4
Systemic sclerosis is an autoimmune disease characterized by progressive fibrosis of the skin and visceral organs. Myasthenia gravis is also an autoimmune disease characterized by weakness and fatigue of skeletal muscles. The symptoms of systemic sclerosis and myasthenia gravis overlap clinically, so the recognition of disease co-occurrence may be delayed. Co-occurrence of myasthenia gravis and systemic sclerosis is very uncommon and usually diagnosed after use of D-penicillamine for treating the systemic sclerosis. We report a case of a 49-year-old female patient who complained of general weakness and was diagnosed with myasthenia gravis. Four months earlier she was diagnosed with systemic sclerosis with Sjogren`s syndrome and her medications did not include D-penicillamine.