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증예(症例) : 장기 생존을 보인 골, 폐 및 복강내 전이가 있었던 원발성 간세포암종 1예
황민호 ( Min Ho Hwang ),김용문 ( Yong Mun Kim ),김정화 ( Jung Wha Kim ),송민섭 ( Min Sub Song ),윤찬호 ( Chan Ho Yun ),김은화 ( Eun Wha Kim ),최용우 ( Yong Ou Choi ),이용웅 ( Yong Woong Lee ) 전북대학교 의과학연구소 2001 全北醫大論文集 Vol.25 No.1
원발성 간암세포암종의 원격전이는 예후가 불량하며 전이병소에 대한 고식적인 수술적 절제, 방사선 치료, 항암화학요법 등과 이들의 병행치료로 효과가 있다고 보고하고는 있으나, 본 증례에서와 같이 좌측 골반부, 우측 견갑부의 골 전이와 폐 전이, 복강내 전이 등 다발성 원격전이된 환자에서의 보고는 없는 상황에서 적극적이며 주기적인 방사선 치료로 비교적 장기 생존을 하며 치료 효과가 있었던 1 예를 보고하는 바이며, 향후에도 적극적이며 다양한 치료 방법들에 대한 보고들이 계속되어야 할 것으로 판단된다. Primary hepatocellular carcinoma(HCC) is one of the most prevalent cancers in the world, particularly in Asia and parts of Africa. Extrahepatic metastasis by blood stream dissemination are encountered in lung. bone, adrenal glands, pancreas, kidney and the spleen. The prognosis of extrahepatic metastasis from HCC remains lethal and average survival time after the time of diagnosis is under 6 months but appropriate local surgical resection of the metastatic region and systemic control with chemotheraphy and radiotheraphy can result in improved quality of survival. We report the case who had been alive 11 months after left iliac bone and then lung, right shoulder joint and peritoneum metastasis with only irradiation.
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Halothane, Enflurane 및 Thalamonal 마취후의 SGOT, SGPT 의 변화
최용우,전세웅,권오경,유승오 대한마취과학회 1984 Korean Journal of Anesthesiology Vol.17 No.1
There are many factors which cause postoperative hepatic drsfunction or necrosis : chronic liver disease, viral infection, septicemia, severe burn, nutritional deficiency, previous or concommitant drug therapy, hypoxia, hypercarbia, hypotension and surgical procedures. Anesthetic agents are not the most common cause of postoperative hepatic dysfunction. But too frequently halothane is blamed for postoperative hepatic dysfunction, while other more likely cavses are ignored. So, in order to in vestigate the effects of halothane, enflurane and thalamonal anesthesia on hepatic function, we compared with serum GOT, GPT level at preoperatively and posto- peratively in 60 patients who had no liver disease previously add had no experience of general anesthesia. We divided them randomly in 3 groups: halothane administered group, enflurane administered group and thalamonal administered group. And serum GOT, GPT were checked preoperatively, postop. 24hrs., and on postop. 6th day. Blood transfusion were not performed during this study. The result of this study reveals that there is no statistically significant difference in changes of SGOT, SGPT between halothane, enflurane and thalamonal group during posto- perative period(p>0.05) . This result shows that the effect of halothane on hepatic function was not significantly different from those of enflurane and thalamonal.
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