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민태 Frame 단백질 유래의 인산화 및 비인산화 펩타이드가 체내 칼슘 흡수에 미치는 영향
김세권(Se Kwon Kim),전유진(You Jin Jeon),변희국(Hee Guk Byun),박표잠(Pyo Jam Park),김규형(Gyu Hyung Kim),최영일(Yong Ri Choi),이연숙(Yeon Sook Lee) 한국수산과학회 1999 한국수산과학회지 Vol.32 No.6
In order to utilize rotein hydrolysate produced from hoki (Johnius belengeri) frame among many different fish processing wastes, hoki frame peptide (HFP) and phosphorylated hoki frame pep6de (PHFP) were prepared, and their calcium absorption accelerating effects were investigated in comparison to control and casein phosphopeptide (CPP). In in vitro experiment, HFP and PHFP inhibited calcium phosphate formation as high as 1.5-fold and 2.5-fold, respectively, comparing to control. In addition, the inhibition rate of calcium phosphate precipitation as increasing concentrations of HFP and PHFP was risen and was similar to that of CPP at 2.0 ㎎/ℓ of PHFP concentration. In in vivo experiment using the rats, the groups fed HFP and PHFP indicated significantly increased calcium content in the femur. In particular, the calcium content in the small intestine of the rat fed PHFP was higher than that of control group by approximately 60%.