Hybvrid Leukeia 2례

최성동,정대철,최우건,김학기,이경수 가톨릭 중앙의료원 가톨릭 암센터 1990 가톨릭 암센터 論集 Vol.4 No.1

신생가토에서 Erythromycin의 위 전정부 및 식도 하부괄약근에 대한 효과

최성동,전정식 대한소아청소년과학회 2000 Clinical and Experimental Pediatrics (CEP) Vol.43 No.1

목 적 : 신생가토에서 motilin과 erythromycin에 대한 위장관 평활근의 수축반응이 성숙가토와 차이가 있는지 알아보기 위해 본 연구를 시행하였다.방 법 : 신생가토와 성숙가토의 위 전정부 및 식도 하부괄약근 근절편을 사용하여 KCl, motilin, erythromycin에 대한 등장성 수축력을 in vitro에서 측정하였고 식도 하부괄약근에 대한 erythromycin의 작용기전을 알아보기 위해서 tetrodotoxin, hexamethonium, atropine, propranolol 및 phentholamine같은 수용체 길항제들과 motilin tachyphylaxis 방법을 사용하였다. Purpose : We studied smooth muscle strips from rabbit gastric antrum and low esophageal sphincter(LES) to explore the difference between newborn and adult rabbit on erythromycin(EM)- induced contractions. Another aim of this study was to determine the mechanism of LES contractile activities induced by erythromycin(EM). Methods : Muscle strips prepared from newborn and adult rabbits were stimulated with agonists such as KCl, motilin and EM, and the isometric tensions were measured. To study the underlying mechanism of EM-stimulated contraction of LES, the receptor antagonsts, including tetrodotoxin, hexamethonium, atropine, propranolol and phentholamine, were used. A high concentration of motilin(1■M) was employed to provoke tachyphylaxis. Results : Antral smooth muscle and LES from newborn rabbits developed less active force than those from adult rabbits when stimulated with KCl, motilin and erythromycin, however, the effective concentrations(EC50s) were similar in both age groups. Antral smooth muscle strips showed both tonic and phasic contractions but LES muscle strips showed only tonic contractions. These findings were observed in both newborn and adult rabbits. The contraction force of antral smooth muscle strips in response to agonists was greater than that of LES. The contractile response of LES to repeated motilin or EM administration was markedly decreased. EM- induced contractions of LES were markedly decreased by motilin tachyphylaxis but were unaffected by tetrodotoxin, hexamethonium, atropine or propranolol plus phentolamine. Conclusion : The data suggest that the contractilities of antrum and LES smooth muscle from newborn rabbit are less than those from adult ones, however, the effective concentratons of EM(EC50) are not different between the two age groups. The results also suggest that erythromycin induces the contraction of rabbit LES via motilin receptor in vitro.

방사선량 측정을 위한 캔위성 개발 및 운용

최성동,이흥섭,염승용,장영근 한국항공우주학회 2012 한국항공우주학회 학술발표회 논문집 Vol.2012 No.11

KRWSAT은 방사선량 측정을 위해 개발된 캔위성으로 제1회 캔위성 경연대회에 참가하기 위해 개발하였다. KRWSAT에는 방사능 센서와 카메라 2대가 탑재 되었다. KRWSAT은 고도 100~200m에서 투하되어 방사선을 측정하고 방사선량 및 사진데이터, 자세데이터, 위치데이터를 지상국으로 송신하게 된다. 본 논문에서는 방사능 측정을 위한 캔위성의 개발 과정과 실제 운용실험을 통한 성능검증을 설명한다. KRWSAT is CanSat for measuring radiation dose. It was developed for the first CanSat Competition in Korea. KRWSAT has a radiation sensor and two cameras. KRWSAT is separated from balloon at about 100~200m of heights, and it measures the radiation dose during descent and then transmits data of radiation dose, image, attitude and location to Ground Station. This paper presents the development process of CanSat for measuring radiation dose and the result of performance verification through test and actual operation.

신생아에서 ECMO 요법

최성동,Choi, Sung Dong 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.8

건강한 만삭에서의 혈중 Motilin 농도와 장관 통과시간과의 관계

최성동,전정식 가톨릭대학 (가톨릭신학대학) 대학원 1994 가톨릭大學醫學部 論文集 Vol.47 No.1

국내 저층 집합주택단지의 계획특성에 관한 현황조사 연구

최성동(Choi Sang-Dong),정진수(Chung Jin-Soo) 대한건축학회 2008 대한건축학회논문집 Vol.24 No.8

The study was progressed with the purpose of using it as a basic data for more various and developed plan of Townhouse through the research of several instances of characteristics of Townhouse, a type of residence. The result of this research is as follow. Firstly, a domestic Townhouse has three to sixteen buildings and their layout types are as standing in a row type, middle garden type decentralization type, and stretch out type in order. Decentralization type, stretch out type shows an aggressive arrangement type which is different to exisiting gathering residential district. Secondly, the characteristics of a plane type has as a plane using a oblique line, a plane surface separated mass, a plane using a part of a oblique line, a design applied an environmental factor and such like. A plan factors showed from an allianced residence type and a plane of a row house would be able to be complemented. Thirdly, the design features have a curved line type, a square type, a prominence and depression type by their various layout type and a plane design. In addition, their general image shows a classic and modern type certainly. The fourth, the Townhouse is mostly situated in a green tract of land even though it is a city type. So its outside space forms a group of a green tract. Facilities show four types such as a independent type, the sunken type, a underground type, and a under deck type.

신경학적 증상을 동반한 수족구병 2례

박기경,최성동,정승연,서병규,강진한,Park, Ki Kung,Choi, Sung Dong,Chung, Seung Yun,Suh, Byung Kyu,Kang, Jin Han 대한소아감염학회 1997 Pediatric Infection and Vaccine Vol.4 No.2

Hand-Foot-Mouth disease, which has a various enanthem-exanthem complex at the tongue, buccal mucosa, hands and feets and buttock area with febrile illness, is usually caused by Coxscakie virus type A(16). Generally, this disease shows self limited course and good prognosis without neurologic manifestations. However, enterovirus 71, which was newly discovered and reported in 1974, can cause the striking features of Hand-Foot-Mouth disease outbreaks and has neuropathogenic potentials of polio-like paralytic illness including aseptic meningitis, meningoencephalitis and respiratory disease. We experienced a case of Hand-Foot-Mouth disease with polyradiculitis manifestations, and a case of Hand-Foot-Mouth disease with meningoencephalitis. Therfore, we report these cases with brief review of related literatures.

榮山江 上水 原水에 암모니아性 窒素 處理工程 比較

최재완,최성동 광주대학교 1997 産業技術硏究 Vol.8 No.-

최근 몇 년 동안 영산강 하류 지역을 取水源으로 하여 정수 처리하여 공급하고 있는 木浦市 夢灘 淨水場의 수질 상태를 관찰할 때 수질 기준 43개 항목중 암모니아성 窒素를 제외한 나머지 全 項目은 대체로 수질기준에 적합하나, 암모니아성 질소는 하절기 2∼3개월을 제외하고는 년중 거의 대부분이 수질 기준 0.5ppm을 초과하고 있으며, 심한 경우 기준치의 14∼15배까지도 검출되는 사례가 있어 이에 대한 대책으로 고도처리 방법을 도입하는 方案을 고려하고 있다. 본 연구에서는 지금까지 알려진 몇 가지 암모니아성 질소 제거공정을 기존의 정수처리 공정에 연결하여 각 대안의 암모니아 除去能力을 파악하여 實際 정수처리 공정으로의 도입 가능성을 연구하였다. 이를 위하여 夢灘 淨水場에서 取水源으로 사용하고 있는 영산강 상수 원수의 암모니아성 질소 濃度변화 및 영산강 수계의 주요 지점의 주요 水質項目을 검사하여 계절에 따른 수질변화 상태를 파악하고, 고도 정수처리 pilot plant를 설치 운영하여 각 단위 공정에서 암모니아성 질소 제거효율을 比較 檢討하였다. The ammonia nitrogen concentration in the raw drinking water of the Yeongsan River is very high. So, it raises a trouble somtimes in drinking water treatment process. This study shows ammonia removal efficiencies of 4 types of pilot plants in Mongtan water treatment plant. Results in this study can be summarized as follows ; 1. The ammonia removal efficiency of the HBC process was higher than that of the RBC by 50∼60%. But in the winter season, ammonia removal efficency of the bio-film process was very poor. 2. The ammonia removal efficiency of O3 and GAC process in the summer season was above 75%. But that of O3 and GaC process in the winter season was below 30%. 3. In 1st pilot plant system with BAC, the ammonia removal efficiency of pre-O3 treatment was 20% on the average but that of post-O3 treatment was below 10%. 4. The most effective ammonia removal processes in the winter season were ion exchange with natural zeolite and breakpoint chlorination. 5. The ammonia removal efficiency of ion exchange with natural zeolite was very good, 70∼100% in all seasons. 6. The breakpoint chlorine dosage must be estimated accurately in prechlorination treatment. And this process requires additional treatment facilities for by-products from chlorination.

무균성 뇌수막염을 동반한 Ramsay Hunt 증후군 1례

연율이,최성동,정승연,서병규,강진한,Yi, Yeon Yul,Choi, Sung Dong,Jeung, Seung Yeon,Suh, Byung Kyu,Kang, Jin Han 대한소아감염학회 1997 Pediatric Infection and Vaccine Vol.4 No.2

Ramsay Hunt syndrome is a viral associated disease with severe otalgia, vertigo, fever, herpetic eruptions on either side of the external auditory meatus and cavum concha, ipsilateral facial nerve palsy and cochleovestibular dysfunction. This syndrome may be the most common cause of unilateral facial paralysis and involvement of both the vestibular and cochlear branch of 8th cranial nerve. And loss of taste sensation may be developed in same involement site. This syndrome affects adults in most cases, and a samll number of children with herpes zoster oticus have been reported. And concomittantly CNS invlovement of this snydrome is very rare. We experienced a 7 years old aged patient of Ramsay Hunt syndrome who had evidence of aseptic meningitis, and this patient showed well reponses with Acyclovir and symptomatic therapy. So, we report this case with brief review of related literatures.

두부 손상후 재발성 세균성 뇌막염과 점액낭종을 보인 환아 1예

서병규,정승연,최성동,전성수,윤소연,강진한 대한감염학회 1998 감염 Vol.30 No.6

저자들은 뇌척수액 비루를 동반한 두부외상이 있은 후 3회에 걸친 재발성 세균성 뇌막염으로 입원치료 받은 남아에서 부비동 전산화 단층촬영을 시행하여 우측 전두동과 전사골동내의 점액낭종 및 우측 전두동 후벽부위의 골절을 확인하였으나 보호자의 동의가 없어 수술을 시행하지 못하고 항생제의 투여와 보존적 요법으로 치료하고 폐렴구균 및 b형 인플루엔자균 백신 접종을 시행한 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Recurrent bacterial meningitis can be caused by acquired or congenital anatomic defects, infection, or alterations in immune mechanism. Intracranial anatomical defects possibly combined with trauma can be the major cause of recurrent bacterial meningitis. Mucocele is a chronic, expansile and cyst-like lesion of the paranasal sinuses, most frequently found in the frontal sinus containing sterile mucoid secretions. Secondary infection of a mucocele may create a pyocele. Although pathogenesis of a primary mucoceles remains uncertain, causatives factors of secondary mucoceles have been suggested to include chronic inflammation, trauma, allergy and obstructing tumors. We experienced a case of recurrent bacterial meaningitis with frontal sinus mucocele, which might be secondary to cranial trauma.