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- 저자 : 최다예(Da Ye Choi) (검색결과 2 건)
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안축장 길이와 시신경 유두의 사상판 두께, 전사상판 두께, 사상판 앞길이와의 상관관계
최다예(Da Ye Choi),한종철(Jong Chul Han),기창원(Chang Won Kee) 대한안과학회 2015 대한안과학회지 Vol.56 No.5
목적: 본 연구는 녹내장의 위험인자 중 하나인 근시안에서 안축장 길이가 사상판 두께, 전사상판 두께, 사상판 앞길이와 의미 있는 관련성이 있는지를 분석하고자 하였다. 대상과 방법: 만 18-58세의 근시 외 다른 안과적 질환이 없는 30명 60안을 대상으로 스펙트럼영역 빛간섭단층촬영기(Spectral Domain Optical Coherene Tomography, SD-OCT)를 이용하여 Enhanced Depth Imaging (EDI) 방법으로 시신경유두의 상부(위 1/3 지점), 중심, 하부(아래 1/3 지점)에서 각각 사상판 두께, 전사상판 두께, 사상판 앞길이를 측정하였다. 안축장의 길이와 사상판 두께, 전사상판 두께, 사상판 앞길이와의 관련성을 각각 선형혼합효과모델(linear mixed model)을 이용하여 분석하였다. 결과: 안축장은 사상판 전체 평균두께 및 상부, 중심부 두께와 유의한 상관관계가 없었으나, 하부의 사상판 두께와는 유의하게 음의선형관계를 나타냈다(p=0.019, β=-7.34). 안축장과 전사상판 두께는 전체 평균두께 및 상부, 중심부, 하부에서 모두 유의한 상관관계가 없었다. 안축장과 사상판 앞길이의 평균두께(p=0.022, β=-17.17) 및 중심부(p=0.026, β=-16.18), 하부(p=0.006, β=-20.63)의 두께는 유의하게 음의 선형관계를 나타냈으며, 상부에서는 유의한 상관관계가 없었다. 결론: 근시안에서 안축장의 길이가 길어질수록 시신경 유두의 아래쪽 사상판 두께가 유의하게 얇아지는 경향을 보이고 사상판 앞길이의 평균두께가 얇아지는 경향을 보인다. <대한안과학회지 2015;56(5):745-752> Purpose: In this study we determined the correlation of axial length to lamina cribrosa thickness (LCT), prelaminar tissue thick-ness (PT), and anterior laminar displacement (ALD) in young healthy eyes. Methods: The optic discs of 60 eyes from 30 young healthy subjects with myopia were scanned using enhanced-depth imaging spectral-domain optical coherence tomography (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany). The LCT, PT, and ALD were measured at the superior midperipheral, middle, and inferior midperipheral of the optic nerve head, respectively. A linear mixed-effects model was used to determine the relationship between the axial length and the LCT, axial length and PT as well as axial length and ALD. Results: The mean, superior midperipheral, and middle LCT were not significantly correlated with axial length. Conversely, the inferior midperipheral LCT was negatively correlated with axial length (p = 0.019, β = -7.34). There was no significant association between axial length and PT. Mean ALD was negatively correlated with axial length (p = 0.022, β = -17.17). Conclusions: In the present study, the inferior midperipheral LCT and mean ALD were negatively correlated with axial length, but PT showed no significant association with axial length. J Korean Ophthalmol Soc 2015;56(5):745-752
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최다예,이정혜,안정현,서연림,우경인,김윤덕,Da Ye Choi,MD,Jung Hye Lee,MD,Jung Hyun Ahn,MD,Yeon Lim Suh,MD,PhD,Kyung In Woo,MD,PhD,Yoon Duck Kim,MD,PhD 대한안과학회 2014 대한안과학회지 Vol.55 No.8
Purpose: Normal squamous cells do not exist in the orbit. Therefore squamous cell carcinoma of the orbit is rare and usually arises as a secondary tumor from distant metastasis or local invasion. The authors herein describe the first case of primary squamous cell carcinoma of the orbit in Korea. Case summary: A 74-year-old female presented with a 2-month history of left upper eyelid swelling and ocular pain. On physical examination, a round, firm, fixed and tender mass was palpable in the superomedial side of the left orbit. Magnetic resonance imaging (MRI) showed 21 mm x 15 mm x 20 mm-sized irregular soft tissue mass with indistinct margin and peripheral enhancement in the superomedial portion of the left orbit, and incisional biopsy of the mass was performed. Histopathological examination showed clusters of squamous cells with polymorphic nuclei and interspersed keratin pearls, consistent with findings of well-differentiated squamous cell carcinoma. Despite extensive systemic work-up, there was no sign of extraorbital malignancy. The patient received left exenteration and adjuvant radiation therapy. Ten months after enucleation, a 12 mm x 14 mm sized firm mass developed on the left forehead, and excisional biopsy and frontalis rotational flap reconstruction were performed. Histopathological examination of the mass was consistent with well-differentiated squamous cell carcinoma. The patient remained alive 17 months after diagnosis without evidence of local recurrence or distant metastasis. Conclusions: Primary squamous cell carcinoma should be considered in the differential diagnosis of acutely progressing tumors of the orbit. J Korean Ophthalmol Soc 2014;55(8):1224-1228
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