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교통부문 미세먼지 배출 현황 및 주요 저감대책의 효과 평가
박상준(PARK, Sangjune),천승훈(CHUN, Seoung Hun),전민택(JEON, Min Taek) 대한교통학회 2017 대한교통학회 학술대회지 Vol.76 No.-
우리나라의 주기적인 고농도 미세먼지가 사회적 문제로 등장한 이래 정부는 미세먼지 저감을 위해 다양한 미세먼지 저감대책을 수립하고 많은 예산을 투입하였으나 아직까지 가시적인 성과는 나타나지 않고 있다. 미세먼지의 발생원인에 대해서는 명확한 정의가 내려져 있지 않지만 중국에서 유입되는 비율이 약 30~40% 정도이며 나머지는 국내에서 발생하고 있는 것으로 추산되며 국내 발생요인으로는 이견이 있으나 교통부문 중 도로에서 약 25%가 발생하고 있다. 특히 도로부문 미세먼지의 주 원인으로 지목된 경유차의 규제와 관련한 다양한 정책이 제시되었으나 경유차 규제로 인한 미세먼지 저감 효과를 객관적으로 평가한 자료는 구축되어 있지 않다. 이러한 측면에서 본 연구는 경유차의 미세먼지 저감효과를 객관적으로 평가하여 저감대책의 효과를 추정하였다. 저감대책 평가대상은 수도권에 등록된 10년 이상 노후경유차 중 저공해화 장치(DPF) 부착이 가능한 차량을 대상으로 미세먼지 저감효과를 산정하였고 DPF 장착으로 저감된 미세먼지 감축에 대한 추정량을 연간 미세먼지로 인한 피해금액으로 환산하여 저감대책의 효과평가가 계량적으로 이루어질 수 있도록 하였다.
정병호(Byung Ho Chung),엄춘성(Chun Sung Eam),조원제(Won Jea Cho),천승훈(Seung Hoon Cheon) 대한약학회 1999 약학회지 Vol.43 No.3
Six novel aryl alkanoic acid derivatives as potential nonsteroidal antiinflammatory and analgesic compounds, were prepared through consecutive reactions of Ullman ether synthesis, NaBH4 reduction, bromination, SN2 reaction with nitrile and alkaline hydrolysis of the nitrile.
Design, synthesis and evaluation of 5-substituted 1-H-tetrazoles as potent anticonvulsant agents
Aimei LIAO,Tiantian Wang,Bangrong Cai,Yi Jin,천승훈,ChangJu Chun,Zengtao Wang 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.4
A series of 5-substituted 1-H-tetrazoles weredesigned and synthesized as potent anticonvulsant agents. Their preliminary anticonvulsant activities were evaluatedusing maximal electroshock and subcutaneouspentylenetetrazole (scPTZ) seizure tests. Neurotoxicity wasdetermined using rotarod test. The results indicated that thecompound 2j in scPTZ model exhibited the ED50 values of83.3 mg/kg, superior to the standard drug ethosuximidewith the maximum activity. In addition, compound 2kshowed the most potent activity in MES model with ED50value of 9.6 mg/kg and TD50 value of 189.5 mg/kg afterintraperitoneal injection in mice, and displayed a highprotective index (TD50/ED50) of 19.7 compared to referenceantiepileptic drugs.
정병호(Byung Ho Chung),조원제(Won Jea Cho),천승훈(Seung Hoon Cheon),박면지(Myun Ji Park),유진철(Jin Cheol Yoo),천문우(Moon Woo Chun) 대한약학회 1997 약학회지 Vol.41 No.2
For the development of antifungal agents, modification of naftifine which exhibits significant antimycotic activity was performed by replacing the naphthalene ring of it to hetero cyclic rings such as morpholine. benzothiazole, piperidine and pyridine derivatives. The synthesized compounds were tested in vitro antifungal activity against five different fungi with naftifine as a comparative antimycotic molecule. From the biological evaluation two compounds, (E)-N-(3-phenyl-2-propenyl)-N-(4-piperidinylmethyl)amine(3d) and (E)-N-(3-phenyl-2-propenyl)-N-(3-pyridylmethyl)amine(3f) showed relatively noticeable activity(MIC=50mcg/ml). On the other hand, the other compounds had no activity.
정병호,조원제,천승훈,박면지,유진철,천문우 전남대학교 약품개발연구소 1997 약품개발연구지 Vol.6 No.1
For the development of antifungal agents. modification of naftifine which exhibits significant antimycotic activity was performed by replacing the naphthalene ring of it to hetero cyclic rings such as morpholine, benzothiazole, piperidine and pyridine derivatives. The synthesized compounds were tested in vitro antifungal activity against five different fungi with naftifine as a comparative antimycotic molecule. From the biological evaluation two compounds. (E)-N-(3-phenyl-2-propenyl)-N-(4-piperidinylmethyl)amine(3d) and (E)-N-(3-phenyl-2-propenyl)-N-(3-pyridylmethyl)amine(3f) showed relatively noticeable activity(MIC=50 ㎍/㎖). On the other hand the other compounds had no activity.
정병호,조원제,천승훈,박면지,유진철,천문우 朝鮮大學校 1998 藥學硏究誌 Vol.19 No.2
For the development of antifungal agents. modification of naftifine which exhibits significant antimycotic activity was performed by replacing the naphthalene ring of it to hetero cyclic rings such as morpholine. benzothiazole. piperidine and pyridine derivatives. The synthesized compounds were tested in vitro antifungal activity against five different fungi with naftifine as a comparative antimycotic molecule. From the biological evaluation two compounds. (E)-N-(3-phenyl-2-propenyl)-N-(4-piperidinylmethyl)amine(3d) and (E)-N-(3-phenyl-2-propenyl)-N-(3-pyndylmethyl)amine(3D) showed relatively noticeable activity(MIC=50㎍/㎖). On the other hand. the other compounds had no activity.
정병호,엄춘성,조원제,천승훈 전남대학교 약품개발연구소 1999 약품개발연구지 Vol.8 No.1
Six novel aryl alkanoic acid derivatives as potential nonsteroidal antiinflammatory and analgesic compounds, were prepared through consecutive reactions of Unman ether synthesis, NaBH₄ reduction, bromination, SN₂ reaction with nitrile and alkaline hydrolysis of the nitrite.