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Babesia gibsoni에 感染된 개의 血淸蛋白分劃에 관한 硏究
印東哲,李周默,蔡俊錫,尹昌模 全北大學校 附設 畜産開發硏究所 1991 畜産開發硏究報告 Vol.4 No.-
To observe the changes of serum proteins according to the process of Babesia gibsoni(B gibsoni) infection, the protozoa(10^8/㎏) were inoculated into the cephalic vein of healthy dogs. The serum proteins of experimentaly infectied dogs were analyzed by cellulose acetate electrophoresis. The results obtained were as follows ; 1. The electrophoretic pattern of serum protein revealed total 6 of bands such as, albumin, α_1 and α_2-globulin, β_1 and β_2-globulin and γ-globulin. 2. Total serum protein showed a decreasing tendency after B gibsoni infection. Albumin and A/G ratio maintained low levels during the period of the infection, although they were not significant. 3. The levels of α_1-globulin significantly increased (P<0.05) in the early stage of the infection. 4. The levels of α_2-globulin and total α-globulin showed highly significant decreases (P<0.01) during the period of the infection. 5. The levels of β_1-globulin and total β-globulin were highly significant increse (P<0.01) in the early stage of infection and decreased later. 6. The γ-globulin constantly increased during the period of the infection (P<0.01). 7. Plasma protein : Fibrinogen (PP : F) ratio revealed a temporally significant increase (P<0.05) after decrease in the early infection.