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박유경,한상윤,채한,배나영,PARK, Yu-Gyeong,HAN, Sang Yun,CHAE, Han,BAE, Nayoung 사상체질의학회 2018 사상체질의학회지 Vol.30 No.3
Introduction The purpose of this study was to systematically review previous studies on Sasang type-specific pathophysiological symptoms in urination and defecation. Methods Peer-reviewed articles on type-specific pathophysiological symptoms of urination and defecation published until September 2016 were extracted from domestic and international six databases. Clinical characteristics from thirteen extracted articles were categorized into three urination domains of appearance of urine, capacity of bladder and urinary discomfort, and three defecation domains of irritability of bowel movement, functional constipation and discomfort from irregularity. Results As for the urination, Tae-Eum type showed dark color with foam, however So-Eum type had frequent urination and sensitivity to dysuria but no nocturia and residual urine sense. As for the defecation, So-Yang type showed frequent urgency and constipation, however So-Eum type reported loose stool. So-Yang type showed varied level of health status depending on defecation irregularity. There were disparities with rectal tenesmus among Sasang types. Discussion Six domains of urination and defecation related type-specific pathophysiological clinical symptoms were provided in this study. This study would contribute to the standardized clinical measures of Sasang typology in the near future.
배뇨 소증 분석과 사상체질 진단을 위한 사상소변기능검사(SUI)의 타당화 연구
채한,이슬,박유경,이정윤,Chae, Han,Lee, Seul,Park, Yu-Gyeong,Lee, Jeongyun 사상체질의학회 2021 사상체질의학회지 Vol.33 No.3
Introduction The Sasang Urination Defecation Inventory was developed to analyze Sasang-type specific pathophysiological clinical symptoms, and its revised Sasang Urination Inventory (SUI) illustrated its clinical usefulness in Sasang type differentiation. However, the correlation with established clinical measures for its concurrent validity were not provided yet. Methods Total of 48 healthy university students were recruited to response Urogenital Distress Inventory-6 (UDI-6) and Overactive Bladder Symptom Score (OABSS) of Western medicine along with the SUI of traditional Korean medicine. The correlation coefficients between UDI-6 and OABSS and SUI were acquired with Pearson's correlation, and Analysis of Variance (ANOVA) and Profile Analysis were used to analyze significant differences in SUI subscale profiles of each Sasang types. Results The SUI-HSS of urogenital hypersensitivity correlated positively with OABSS (r=0.442, p<0.01), and the SUI-DIS of urinary discomfort positively with UDI-6 (r=0.289, p<0.05). Interestingly, the SUI-total was correlated positively with age (r=0.326), height (r=0.318) and weight (r=0.304). The SUI-DIS for urinary discomfort of So-Yang (9.48±2.11) type was significantly (p<0.05) higher than that of Tae-Eum (7.2±2.90) type. And SUI subscale profiles of each Sasang type were significantly (Wilks' Lambda=0.792, F=2.723, p=0.034) distinctive to each other. Discussion The acceptable convergent validity of SUI was shown using established measures of urogenital symptoms. The SUI might be used as an objective traditional Korean clinical measure for Sasang type differentiation and urological patients.
한국인에서 Interleukin 1β 유전자다형성에 따른 위산분비능
이인석 ( Lee In Seog ),한혜원 ( Han Hye Won ),조유경 ( Jo Yu Gyeong ),김세희 ( Kim Se Hui ),이수민 ( Lee Su Min ),이학성 ( Lee Hag Seong ),김상우 ( Kim Sang U ),최명규 ( Choe Myeong Gyu ),채현석 ( Chae Hyeon Seog ),김재광 ( Kim Ja 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<배경> IL-1β는 Helicobacter pylori 감염 후 증가되는 염증물질로서 IL-1β의 유전자다형성은 위내저산증과 연관 있는 것으로 알려져 있다. 저자는 IL-1β 유전자다형성에 따른 위산분비능에 대하여 연구하였다. <방법> 2001년 9월-2003년8월까지 강남성모병원 소화기내과를 방문한 환자 중 지원자를 대상으로 IL-1β -511,-31 및 IL-1RN 유전자다형성여부를 조사하고, 상부위장관내시경, 혈중 gastrin/ pepsinog