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진택현 ( Taek Hyun Jin ),지유진 ( Yu Jin Jee ),류동목 ( Dong Mok Ryu ),권용대 ( Yong Dae Kwon ),이덕원 ( Deok Won Lee ) 한국조직공학·재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
The present study was performed to examine the genes expression during osseointegration of dental implant. Machined, resorbable blast media(RBM), oxidized surface treated implants were used in this study. This 3 different surface treated implants with 5 mm in length and 3 mm in diameter were placed in the tibia of the rabbit. In the control group, only bone defect was made. Rabbits were sacrificed for histomophormetric evaluation and GeneFishing analysis at 1, 2, 6 weeks after implant placement. In histomorphometric evaluation with the measurement of BIC(bone-implant contact ratio) and BA(bone area ratio), RBM surface implant showed highest value in both BIC and BA, and machined surface implant showed lowest score. In GeneFishingTM screening analysis, 52 DEGs(differentially expressed genes) were expressed in 1 week group and 50 DEGs in 2 weeks group. This result suggests that implant surface treatment modulates the gene expression of bone tissue around dental implant. And then, direct sequencing and BLAST of 33 DEGs were performed. 6 DEGs were identified as known genes. Other DEGs were EST(expressed sequence tag) or unknown genes. This results suggests that many unknown genes are related to osseointegration of dental implant.
이상철(Sang Chull Lee),김여갑(Yeo Gab Kim),류동목(Dong Mok Ryu),이백수(Baek Soo Lee),윤옥병(Ok Byung Yoon),진택현(Taek Hyun Jin) 대한구강악안면외과학회 1998 대한구강악안면외과학회지 Vol.24 No.3
This is a retrospective study on condylar fracture of mandible. The study based on a series of 112 patients who had treated for the fractures of mandibular condyle on KyungHee Dental Hospital from January , 1989 to August. 1997. We studied the age and sex distributions, causes of fractures, location of fractures and so on. The results as follows; 1. The ratio of male:female was 4:1, and the highest frequency of condylar fractures was registered among patients aged to 21 to 30 years. 2. The most common cause of condylar fracture was fall-down(47.7%), followed in incidence by direct-blow(27.9%) and traffic accidents(20.7%). 3. Subcondylar fracture had highest incidence(50%), and followed by condyle head(27.4%) and condylar neck(22.6%). 4. 9.7% of condylar fractures had occurred bilaterally, and in cases of bilateral condylar fractures, condyle head fracture(58.33%) was highest incidence. 5. Mandibular symphysis was most commonly involved in condylar fracture(63.4%), and 27.7% of condylar fractures had not any other mandibular fractures.
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진택현,오승환,류동목,김여갑,이상철 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.1
This is a case of bony ankylosis of right temporomandibular joint with mild facial asymmetry resulted from trauma, which bring about the right condylar fracture, and corrected by interpositional arthroplasty with temporal fascia flap and coronoidectomy. The postoperative results were functionally and esthetically good, but continued osbervation is necessary to evaluation of abnormal bony growth and reankylosis.