골노화 요소 기반 생물학적 나이 예측모델개발 및 낙상과 보행에 따른 생물학적 나이

지혜미 ( Hae Mi Jee ) 한국운동생리학회 2016 운동과학 Vol.25 No.1

PURPOSE: The aims of this study were to identify bone health related biomarkers, develop an osseous health based biological age (BA) prediction model, and investigate its applicability. METHODS: Data of a total of 4,644 eligible male participants (age≥30 years) examined for bone health from the 2010 and 2008 Korea National Health and Nutrition Examination Survey were used in the study. Among 15 bone health related variables, 5 biomarkers were selected through a parsimonious exclusion procedure and correlation analysis between the parameters and chronological age. Principal component analysis was applied to extract the principal component factors. Through application of CA and adjustment procedure, a BA prediction model based on osseous biomarkers was obtained. Applicability of the model was assessed. First, history of fall was compared between the fall and no-fall groups. Second, three groups were compared for their continuous walking durations. All groups were compared by three age groups. RESULTS: BA was significantly greater than CA in the fall group by 5.60 years for the older group. As for the walking duration, BA was significantly less by 5.14 and more by 6.51 years than CA for the older groups with more than 2 hours and less than 1 hour of walking durations, respectively. CONCLUSIONS: BA prediction model based on five non-invasive osseous biomarkers may be applicable to predict bone health related conditions. It may be used as a health promotional tool in a health related field to deter or even reverse health deterring factors.

스쿠버 다이빙 활동 시 임상적 건강과 기초체력의 주요 요인 조사

지혜미(Jee Hae-Mi),전태원(Jun Tae-Won),장혁기(Chang Hyuk-Ki) 한국체육과학회 2011 한국체육과학회지 Vol.20 No.2

The purpose of this study was to identify the major scuba diving factors that may affect the safety of the activity as well as the directional guideline for the future. A panel was composed of 18 scuba diving related experts and through intuitive judgements, results were converged in three rounds with pre-defined stop criterion. Three major scuba diving factors were identified through first round which were ‘medical screening of health and physical fitness.’ and ‘physical fitness’ in the order of higher identification. Each major factors were categorized in detail and through two more rounds, each items were scored with 5-point Likert scaling. In the ‘health and physical fitness’ factor, items such as ‘need for increased scuba diver medical staff(4.94),’ and ‘need for increased facility, equipment and medical information(4.65).’ were scored the highest. In the ‘basic physical fitness’ factor, ‘cardiovascular fitness(4.69),’ ‘flexibility(4.21),’ and ‘strength(4.18)’ were scored the highest. In conclusion, basic physical fitness should be considered with supportive medical staff, facility. For prevention and safety, each diver should evaluate one's capacity and acquire customized training periodically. Moreover, adequate physical activity should be conducted composed of cardiovascular fitness, flexibility and strength training along with other basic physical fitness factors such as power, agility, and endurance.

한국남성의 복부 비만과 건강체력이 동맥경화도에 미치는 영향

김용환 ( Yong Hwan Kim ),지혜미 ( Hae Mi Jee ),송성일 ( Sung Il Song ),김주찬 ( Joo Chan Kim ),고덕한 ( Duk Han Ko ),진영수 ( Young Soo Jin ) 대한스포츠의학회 2012 대한스포츠의학회지 Vol.30 No.1

The purpose of this study was to find out the relationship between waist circumference, muscular strength, flexibility, and brachial-ankle pulse wave velocity (baPWV). Furthermore, the cut-off values of the physical fitness factors according to the baPWV were also calculated. The study was derived with total of 1,562 males (1,116 middle-aged and 446 old-aged). They were tested participant`s baPWV, waist circumference, cardiopulmonary fitness, grip strength and flexibility. The results of this study is that the baPWV of the middle-aged men did not show significant changes in relationship with the waist circumference and physical fitness factors. The old-aged group with normal abdominal fat and high physical fitness level (group 4) showed significant baPWV values in comparison to those with waist circumference and low physical fitness levels (group 1); cardiorespiratory fitness p=0.026, grip strength p=0.000, flexibility p=0.000. The cut-off values of the physical fitness such as cardiorespiratory fitness, grip strength, flexibility according to the baPWV were 31.2 mL/kg/min (area under curve [AUC], 0.692; p=0.027), 37.0 kg (AUC, 0.588; p=0.014), and 1.0 cm (AUC, 0.589; p=0.014), respectively. In conclusion, these results demonstrate that waist circumference, cardiorespiratory fitness as well as muscular strength and flexibility effect inversely on arterial stiffness.

호흡기 바이러스의 연령별, 성별, 계절별에 따른 유병률 변화: 단일기관에서 10년 동안 호흡기 질환으로 입원한 소아 환자를 중심으로

이승진 ( Seung Jin Lee ),이신혜 ( Shin Hae Lee ),하은교 ( Eun Kyo Ha ),신윤호 ( Youn Ho Sheen ),성명순 ( Myong Soon Sung ),정영호 ( Young-ho Jung ),이경석 ( Kyung Suk Lee ),지혜미 ( Hye Mi Jee ),한만용 ( Man Yong Han ) 대한천식알레르기학회(구 대한알레르기학회) 2017 Allergy Asthma & Respiratory Disease Vol.5 No.6

Purpose: It is well known that respiratory viral infection has epidemiological characteristics, including season. This study aimed to investigate the patterns of the prevalence of common respiratory viruses during a period of 10 years with regard to age, sex, and season in Korean children. Methods: From June 2006 to November 2016, we obtained 11,798 specimens from patients aged less than 18 years who were admitted with lower respiratory infections. Ten respiratory viruses were detected using multiplex reverse transcription-polymerase chain reaction. Results: Of 11,798 specimens, at least 1 virus was detected in 4,845 (41.1%). Respiratory syncytial virus (RSV, 18.9%) was the most common virus detected, followed by human rhinovirus (HRV, 14.8%), adenovirus (9.5%), and human bocavirus (HBoV, 7.4%). The detection rate of HRV was higher in male subjects (male 60.0% vs. female 40.0%, P=0.004), but the other viruses had no significant differences with regard to sex. The subjects who were positive for RSV test were youngest (median, 10.5 months; interquartile range, 3.0-25.0 months), followed by human coronavirus (median, 13.0 months), HRV (median, 14 months), and parainfluenza (median, 14 months). HBoV was most commonly detected in spring (29.3%), enterovirus in summer (25.8%), HRV in fall (22.6%), and RSV in October and winter (22.6%). Conclusion: We found that the prevalence of respiratory viruses in Korean children during a period of 10 years was associated with age, sex, and season when the infection occurred. Further nationwide data is warranted to infer clinical implication of our results. (Allergy Asthma Respir Dis 2017;5:320-325)

남성 노인의 순발력, 유연성에 따른 대사증후군의 유병률과 임계값에 관한 연구

김용환 ( Young Hwan Kim ),송성일 ( Sung Ll Song ),이혜영 ( Hye Young Lee ),지혜미 ( Hae Mi Jee ),김주찬 ( Joo Chan Kim ),이한준 ( Han Joon Lee ),고덕한 ( Duk Han Ko ),김소정 ( So Jung Kim ),김신애 ( Shin Ae Kim ),정진욱 ( Jin Wook 대한스포츠의학회 2010 대한스포츠의학회지 Vol.28 No.2

The purpose of the study was to find out the age-adjusted odds ratio of the metabolic syndrome and the associated cut-off values of the physical fitnessfactors of the elderly males in their 60s and 70s. 477 participants were tested for the cardiorespiratory fitness (VO2max), power, flexibility as well as blood battery and abdominal circumference for the metabolic syndrome status. As a result, 32.2% of the participants had metabolic syndrome with the associated cut-off values of the power and flexibility as 29.0 cm (areas under curve [AUC]: 0.57, p=0.029) and 0.6 cm (AUC: 0.54, p=0.028), respectively. The cardiorespiratory fitness showed no significant difference prevalence rate between groups. The prevalence rate was calculated by dividing the participants into high and low groups. The metabolic syndrome prevalence rate for the low power group was 1.63 (p<0.030) and low flexibility group was 2.01 (p<0.002). The cardiovascular fitness showed no significant prevalence rate.