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증례 : 폐암에 동반되어 동맥 혈전색전증으로 발현된 Trousseau 증후군 1예
조영재 ( Young Jae Cho ),김희정 ( Hee Joung Kim ),이지은 ( Ji Eun Lee ),조준성 ( Joon Sung Joh ),한성구 ( Sung Koo Han ),심영수 ( Young Soo Shim ),유철규 ( Chul Gyu Yoo ) 대한내과학회 2007 대한내과학회지 Vol.72 No.6
저자들은 임상적으로 하지 동맥의 경색이 발생한 후 그 원인 질환으로 폐선암이 진단되었고, 추후 다발성 및 재발성 경색이 발생하였던 1예를 경험하였기에 문헌고찰과 함께 이에 보고한다. 악성 종양에 동반된 과응고성이 이러한 다발성 경색의 원인이 될 수 있으며, 저분자량헤파린이 그 치료에 도움을 줄 수 있다고 알려져 있다. In 1865, Armand Trousseau recognized the first relationship between a neoplastic disease and a thromboembolic disorder. Since then, many cases have been reported and have been termed as Trousseau`s syndrome. One mechanism of hypercoagulability was considered to be the activation of coagulation systems by a tissue factor secreted by neoplastic cells, but accurate pathophysiology still remains unknown. We report a case of a multiple and recurrent thromboembolism in a patient with adenocarcinoma of the lung. A woman aged 68 years with an acute thromboembolism at her right distal calf artery was diagnosed as having adenocarcinoma of the lung. She underwent a thromboembolectomy two times, but had to receive surgery for a below knee amputation. Multiple and recurrent thromboembolic events then attacked her cerebral and coronary arteries, which led to cerebral and myocardial infarctions. She expired by a progression of the adenocarcinoma of the lung after about six months. (Korean J Med 72:673-678, 2007)
황용일 ( Yong Il Hwang ),김현정 ( Hyun Jung Kim ),원왕연 ( Wang Youn Won ),조준성 ( Joon Sung Joh ),오연목 ( Yeon Mok Oh ),정기석 ( Ki Suck Jung ),이상도 ( Sang Do Lee ) 대한내과학회 2012 대한내과학회지 Vol.83 No.4
Background/Aims: Chronic obstructive pulmonary disease (COPD) often coexists with co-morbid conditions that significantly affect the prognosis. Although depression frequently coexists with COPD, little about how to screen for depression in COPD patients is known. We report the effectiveness of depression screening in patients with COPD and of the instruments used for this purpose. Methods: We performed a systematic literature review of the domestic (Research Information Sharing Service, KoreaMed, and Kmbase) and international (Medline, Embase, Cochrane library) databases using COPD AND depression AND screening tools as key words. Results: No study directly evaluated the effectiveness of screening for depression in COPD patients. However, depression was present more frequently in patients with COPD. COPD patients with depression were also more likely to be in poor health. A total of eight screening instruments for depression were translated into Korean. All had similar reliabilities and internal consistencies. Conclusions: Screening of COPD patients for depression is necessary because individuals with this condition are more likely to suffer from depression, which has a negative impact on health. The choice of depression screening instruments may need to be based on considerations of simplicity. (Korean J Med 2012;83:468-475)
증예(症例) : 심방중격결손증 환자에서 기이성 색전으로 발생한 신장 경색 1례
정현일 ( Hyun Il Jeong ),최승민 ( Seung Min Choi ),조준성 ( Joon Sung Joh ),최광준 ( Gwang Jun Choi ),곽동명 ( Dong Myoung Kwak ),박상민 ( Sang Min Park ),양성욱 ( Sung Wook Yang ) 전북대학교 의과학연구소 2009 全北醫大論文集 Vol.33 No.2
본 저자들은 심방중격결손증이 있던 환자에서 심부정맥혈전증과 급성 폐혈전색전증이 일어난 후 기이성 색전으로 신장경색증이 발생한 환자를 보고하고자 한다. Coexistence of pulmonary embolism and systemic arterial embolism suggest the diagnosis of paradoxical embolism which suggest the presence of intracardiac defects such as patent foramen ovale. Atrial septal defect(ASD) in uncommon cause of paradoxical embolism. And also renal infarction is uncommon sequelae of paradoxical embolism. Here, we present rare case of renal infarction due to paradoxical embolism via ASD and a review the literature.
이승훈 ( Seung Hun Lee ),이다현 ( Da Hyun Lee ),문가슬 ( Ga Seul Moon ),나수지 ( Su Sie Rah ),김상용 ( Sang Yong Kim ),조한나 ( Han Na Cho ),조준성 ( Joon Sung Joh ) 전북대학교 의과학연구소 2011 全北醫大論文集 Vol.35 No.2
Tuberculosis accompanied by idiopathic thrombocytopenic purpura is uncommon worldwide. A 77-year-old woman who presented with hemorrhage was diagnosed with idiopathic thrombocytopenic purpura and tuberculosis. The patient was unresponsive to steroid and high dose IV γ-globulin, however both diseases improved with anti-tuberculosis medication. Although the correlation between the two diseases is not clear, an immunological mechanism is thought to be involved. A patient diagnosed with idiopathic thrombocytopenic purpura in an area with a high prevalence of tuberculosis may also require an evaluation for tuberculosis.
스트렙토마이신 정맥주사를 이용한 폐결핵의 치료의 대안적 접근방법
김상용,현기 크리스쳔 홍,김종훈,유지원,최한섶,정연태,조준성 대한감염학회 2010 감염과 화학요법 Vol.42 No.1
Streptomycin is currently utilized to treat advanced tuberculosis in Korea. However, the usefulness of intravascular streptomycin is not fully understood. In this study, streptomycin was administered intravenously in 30 patients. Intravenous administration of streptomycin may be a useful route of administration without undesirable toxicities.