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        위십이지장궤양에서 Famotidine 의 효과

        나용호 ( Yong Ho Nah ),박석 ( Suk Park ),김혁제 ( Won Sup Cho ),조원섭 ( Hyuk je Kim ) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.1

        N/A We conducted a single-blind randomized controlled study of 60 patients with endoscopically proven duodenal or gastric ulcers to study the efficacy and safety of famotidine, a new potent histamine H2-receptor antagonist, in accelerating healing and pain relief as compared with placebo. The famotidine group, comprising 16 cases of gastric ulcers and 20 cases of duoderial ulcers, received famotidine 20mg twice daily (after breakfast and befor bedtime). Pretreatment characteristics were similar in all four treatment groups. The duration of treatment was eight weeks for gastric ulcer and six weeks for duodenal ulcer. Healing was determined by endoscopy after completion of the trial. By the end of study, 87.5% of gastric ulcers and 90% of duodenal ulcers were healed in the famotidine group compared to 36% of gastric ulcers and 38% of duodenal ulcers in the placebo group, respectively. Famotidine 20mg bid was superior to placebo in healing ulcers. The time until relief of pain was significantly less for patients on famotidine than for those on placebo. Relief of ulcer pain usually occurred within the first week of famotidine treatment in gastric or duodenal ulcers. Therapy was generally well tolerated and there was few side effects with famotidine treatment. These results indicate that famotidine 20mg bid is effective and safe for the treatment of gastric or duodenal ulcer.

      • KCI등재후보

        한국 성인에서 인체계측치

        나용호,송주흥,최인태,채수인,박석,김혁제,조원섭 대한내과학회 1987 대한내과학회지 Vol.32 No.3

        Nutritional assessment is a rational prerequisite to the provision of adequate patient care. Anthropometric measurement is relatively simple but valuable method of nutritional assessment and current)y widely used in clinical practice. But Korean anthropomeric data were not yet obtained. To obtain anthropometric data in Korean, we measured body weight, height, triceps skin- fold thickness (TSF), and midarm circumference (MAC) of 2021 Korean aged from 16 to 9S years. The midarm fat area (MAFA) and midarm muscle area (MAMA), based on the measurement of TSF and MAC, were calculated. The results were summarized as follows; 1) The mean value of body weight of Korean, under 65 years old was 65.6(±8.3)kg in male, 54.2(±6.9)kg in female; over 65 years old 58.8(±9.5)kg in male, 48.8(±9.4)kg in female. 2) The mean value of the height of Korean, under 65 years old was 169.0(±5.6)cm in male, 157.7(±4.7)cm in female; over 65 years old 166.1(±5.1)cm in male, 148.0(±6.8)cm in female. 3) The mean value of MAC of Korean, under 65 years old was 27.5(±2.7)cm in male, 26.6(±3.0)em in female; over 65 years old 25.4(±2.7)cm in male, 24.5(±3.6)cm in female. 4) The mean value of TSF of Korean, under 65 years old was 12.2(±5.7)mm in male, 20.6(±7.1)mm in female; over 65 years old 11.4(±5.4)mm in male, 16.1(±6.8)mm in female, 5) The mean value of MAMA of Korean, under 65 years old was 45.2(±10.2)cm² in male, 32.8(±9.1)cm² in female; over 65 years old 38.3(±7.4)cm² in male, 30.6(±7.8)cm² in female. 6) The mean value of MAFA of Korean, under 65 years old was 15.6(±7.3)cm² in male, 24.2(±9.2)cm² in female; over 65 years old 13.7(±7.4)cm² in male, 18.1(±9.2)cm² in female. This study shows that anthropometric data of Korean are considerably lower than those published in western country. These results suggest racial difference. So nutritional assessment in Korean should be done by reference chart from Korean.

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