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        다발성 중증 외상 환자들의 치료에 대한 응급 외상팀 운영의 효과

        이성화 ( Seong Hwa Lee ),조석주 ( Suck Joo Cho ),염석란 ( Seok Ran Yeom ),류지호 ( Ji Ho Ryu ),정진우 ( Jin Woo Jung ),한상균 ( Sang Kyun Han ),김용인 ( Yong In Kim ),박맹렬 ( Maeng Real Park ),김영대 ( Young Dae Kim ) 대한외상학회 2009 大韓外傷學會誌 Vol.22 No.2

        Purpose: We performed this study to determine how the emergency trauma team affects the treatment of patients with multiple severe trauma and to discuss the effect and the direction of the emergency trauma team`s management. Methods: We performed a retrospective analysis of 518 patients who visited our emergency department with severe trauma from August 2006 to July 2008. We divided the severe trauma patients into 2 groups: patients before and after trauma team management (Group 1 and Group 2). Then, we compared demographic characteristics, mechanisms of injury, and treatment outcomes (lengths of stay in the ED, admission ratio, and in-hospital mortality) between the 2 groups. In the same way, patients with multiple severe trauma were divided into 2 groups, that are patients before and after trauma team management (Group 3 and Group 4) and analyzed. Results: There was no significant difference, except mean age, between groups 1 and 2. In group 4 patients, compared to group 3 patients, the lengths of stay in the ED were lower (p value<0.001), and the admission ratio were higher (p value=0.017), but there was no significant difference in the in-hospital mortality between the groups 3 and 4. Conclusion: When patients with multiple severe trauma visit the ED, the emergency trauma team`s management can decrease the lengths of stay in the ED and increase the admission ratio, but does not produce a decrease in the in-hospital mortality rate. Further investigations of emergency trauma team management are needed to improve treatment outcomes for patients with multiple severe trauma. (J Korean Soc Traumatol 2009;22:172-78)

      • 角膜創傷治癒에 對한 組織化學的硏究

        趙錫周 中央醫學社 1940 中央醫學 Vol.9 No.2

        In studies of corneal wound healing, G?tterbock (1871) and others proposed the theory of "mechanical sliding" of the corneal epithelium, and Wyss (1879) and others proposed the theory of epithelial cell multiplication. With regard to the appearance of inflammatory cells in the stroma, Cohnheim (1867), Robb and Kuwabara (1962) pointed out that leucocytes reached the corneal wound through the "conjunctional secretions". However, Maumenee and Kornblueth (1949), Heydenreich (1957) and Weimar (1958) observed the migration. of leucocytes from perilimbal vessels into the corneal wound through stromal tissue. With regard to the demonstration of stromal metachromasia, Aurell (1954) pointed out that the greatest stromal metachromasia appeared of the end of the second week and then gradually decreased, with regard to content of stromal mucopolysaccharide, Francois and Rabaey (1956) stated that the quantity of mucopolysaccharide was not changed in spite of heavier local staining reaction. During corneal wound healing, Wolter (1958) differentiated the newly formed fibroblasts from the original activated stromal cells. Weimar (1958) emphasized the important role of fibroblasts in contributing to stromal regeneration, and Dunnington (1958) noted that the newly developed or covered corneal epithelium of the wound exerted a profound effect upon fibroblast formation in the healing corneal wound. In its absence fibroblast formation was decreased and did not reach a normal rate until the epithelium had grown across the anterior surface of the incision. Recently many histochemical studies of the cornea in experimental animals and human being have been presented. Wislocki (1952) presented in detail the histochemical characteristics of the eye of the normal rhesus monkey. Ichikawa (1954) observed the fluctuation of nucleic acids and mucopolysaccharide of the cornea during corneal wound healing. Since deConcillis (1934) first reported the enzymatic activity of alkaline phosphatase in the intact retina of rabbit, Bonting et al. (1961) demonstrated adenosine triphosphatase in the intact ocular tissue of several animals and Lessell and Kuwabara (1964) have established in detail the action and presence of various phosphatases including adenosine di and triphosphatases in intact ocular tissues of various animals. The author was interested the fact that in wound healing of the avascular tissue of the cornea there is a different pattern from that of the ordinary tissue. In this experiment the author attempted to study histological and histochemical reactions of the cornea in the healing processes of artificially produced corneal wound.

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